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The Radiobiological Significance of Spatial and Temporal Distribution of Energy Absorbed from Ionizing Radiations

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Physical and Chemical Mechanisms in Molecular Radiation Biology

Part of the book series: Basic Life Sciences ((BLSC,volume 58))

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Abstract

The cells of higher organisms respond in a non-linear fashion to the energy absorbed from ionizing radiation. However, there appears to be no indication of a dependence that is of a higher power than the square of the absorbed energy. This relatively simple alternative permits operational definitions of two types of injuries, termed lesions and sublesions, and a basic description in terms of dual radiation action. There are, however, various complicating factors and uncertainties. Further progress requires the development of a modified microdosimetry that incorporates energy transport, a more complete treatment of saturation and especially a specific identification of what is probably damage to DNA.

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Authors
  1. Harald H. Rossi
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Editors and Affiliations

  1. Pacific Northwest Laboratories, Richland, Washington, USA

    William A. Glass

  2. U.S. Department of Energy, Germantown, Maryland, USA

    Matesh N. Varma Ph.D.

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© 1991 Plenum Press, New York

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Rossi, H.H. (1991). The Radiobiological Significance of Spatial and Temporal Distribution of Energy Absorbed from Ionizing Radiations. In: Glass, W.A., Varma, M.N. (eds) Physical and Chemical Mechanisms in Molecular Radiation Biology. Basic Life Sciences, vol 58. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-7627-9_11

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  • DOI: https://doi.org/10.1007/978-1-4684-7627-9_11

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-7629-3

  • Online ISBN: 978-1-4684-7627-9

  • eBook Packages: Springer Book Archive

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