Abstract
Environmental influences are held responsible for more than 80% of human cancers (Peery, 1975; Davis, 1975). A large number of factors have been incriminated including industrial chemicals and pollutants, food additives, fungal products, tobacco smoking, naturally occurring plant products, and deficiences or excesses of diet. The notion that environmental factors are the major determinants in the etiology of human cancers is based on the uneven geographical distribution of the disease (Drasar and Irving, 1973; Armstrong and Doll, 1975). Armstrong and Doll (1975) have studied incidence rates for 27 cancers in 23 countries and mortality rates for 14 cancers in 32 countries. Stomach cancer is high in Japan, South America, and Eastern Europe, and low in North America and Western Europe. An exactly inverse geographical distribution is noted for cancers of the colon, breast, corpus uteri, ovary, and kidney.
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Goldin, B.R., Gorbach, S.L. (1979). Microbial Factors and Nutrition in Carcinogenesis. In: Draper, H.H. (eds) Advances in Nutritional Research. Advances in Nutritional Research, vol 2. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-9931-5_6
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DOI: https://doi.org/10.1007/978-1-4613-9931-5_6
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