Abstract
Like many tissues in the human body, bone is constantly undergoing changes in its microstructure. The homeostasis of bone can be described as a dynamic equilibrium existing between resorption and deposition of mineral. Although each bone has a genetically determined minimal mass and structure, the normal state of bone in the physiologic environment is a consequence of adaptations to various chemical and physical stimuli (Lanyon 1984). These adaptations are achieved through an active remodeling of the internal and surface characteristics (e.g., structure and mineral content) of bone.
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Shin, H.Y., Iveson, R.D., Blumenstock, F.A., Bizios, R. (1994). Osteoblast Responses to Steady Shear Stress. In: Mow, V.C., Tran-Son-Tay, R., Guilak, F., Hochmuth, R.M. (eds) Cell Mechanics and Cellular Engineering. Springer, New York, NY. https://doi.org/10.1007/978-1-4613-8425-0_7
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DOI: https://doi.org/10.1007/978-1-4613-8425-0_7
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