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Ethanol-Induced Hypertension: The Role of Acetaldehyde

  • Chapter
Pathophysiology of Heart Failure

Part of the book series: Developments in Cardiovascular Medicine ((DICM,volume 168))

Abstract

Within the hypertensive population, as many as 30% may have alcohol-induced hypertension [1]. Increased prevalence of hypertension in heavy drinkers was first described by Lian in 1915 [2], and over the past 20 years, epidemiological and clinical studies have confirmed this association [3–6]. Recently, using animal models, the biochemical mechanisms whereby ethanol intake leads to hypertension are beginning to be understood [7–15].

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Authors
  1. Sudesh Vasdev
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  2. Brendan Barrett
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  3. Linda Longerich
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  4. Carol Ann Ford
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Editors and Affiliations

  1. MRC Group in Experimental Cardiology Division of Cardiovascular Sciences St. Boniface General Hospital Research Centre Faculty of Medicine, University of Manitoba, Winnipeg, Canada

    Naranjan S. Dhalla (Distinguished Professor), Pawan K. Singal (Professor) & Robert E. Beamish (Professor Emeritus) (Distinguished Professor),  (Professor) &  (Professor Emeritus)

  2. Department of Internal Medicine Aoto Hospital, Jikei University School of Medicine, Tokyo, Japan

    Nobuakira Takeda (Associate Professor) (Associate Professor)

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Vasdev, S., Barrett, B., Longerich, L., Ford, C.A. (1996). Ethanol-Induced Hypertension: The Role of Acetaldehyde. In: Dhalla, N.S., Singal, P.K., Takeda, N., Beamish, R.E. (eds) Pathophysiology of Heart Failure. Developments in Cardiovascular Medicine, vol 168. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1235-2_6

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