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Growth Factors and Growth Factor Receptors in Chronic Pancreatitis, and the Relation to Pancreatic Cancer

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Pancreatic Cancer

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Abstract

Chronic pancreatitis is an inflammatory disease of the pancreas that leads to persistent and progressive morphological and functional alterations of the whole organ and in its terminal state severe exocrine and endocrine insufficiencies are present. (1–3). Morphologically, chronic inflammation of the pancreas is also associated with pancreatic head enlargement, calcifications of the parenchyma, cysts, necrosis, and pancreatic stones (4–6). The continuous tissue destruction and subsequent remodeling causes finally the two major clinical symptoms: upper abdominal pain and maldigestion.

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Authors
  1. Helmut Friess
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  2. Pascal Berberat
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  3. Markus W. Büchler
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Editors and Affiliations

  1. UCLA School of Medicine, Los Angeles, CA, USA

    Howard A. Reber MD

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Friess, H., Berberat, P., Büchler, M.W. (1998). Growth Factors and Growth Factor Receptors in Chronic Pancreatitis, and the Relation to Pancreatic Cancer. In: Reber, H.A. (eds) Pancreatic Cancer. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-4612-1810-4_3

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  • DOI: https://doi.org/10.1007/978-1-4612-1810-4_3

  • Publisher Name: Humana Press, Totowa, NJ

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