Abstract
Insulin-dependent diabetes mellitus (IDDM) results from damage to the insulin-producing tissue of the pancreas. Thus, any cure for this disease must involve replacement of damaged islet tissue, by grafting this tissue either as a free islet graft or in the form of pancreas transplantation. In the case of a disease like diabetes, which is not immediately life-threatening, the long-term use of antirejection drugs may not be justified; the risk of antirejection therapy could be more dangerous than diabetes itself.
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Calcinaro, F., Wegmann, D.R., Lafferty, K.J. (1994). Pathogenesis of Autoimmune Diabetes. In: Draznin, B., LeRoith, D. (eds) Molecular Biology of Diabetes. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-4612-0241-7_4
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DOI: https://doi.org/10.1007/978-1-4612-0241-7_4
Publisher Name: Humana Press, Totowa, NJ
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