Skip to main content

Packed-bed adsorption theories and their applications to affinity chromatography

  • Conference paper
  • First Online:
Chromatography

Part of the book series: Advances in Biochemical Engineering ((ABE,volume 25))

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Abbreviations

a:

interfacial area of solid phase per unit interstitial void volume

C:

concentration of adsorbate in the interparticle void space

Ci :

concentration of adsorbate in the intraparticle pore space

Co :

feed concentration

C*:

concentration of adsorbate at the interface (Eq. 11)

De :

effective particle-phase diffusivity in homogeneous solid model (Eq. 4)

Dp :

particle-phase diffusivity

Dx :

axial dispersion coefficient

Dp :

diameter of solid particles

H:

height equivalent to a theoretical plate (HETP) in the plate model

h:

reduced H, h=H/dp

Kf :

overall coefficient of mass transfer for fluid phase

Kf :

the constant corresponding to the mass transfer coefficient in the fluid side (Eq. 11)

Kp :

the constant corresponding to the mass transfer coefficient in the particle side (Eq. 10)

k:

rate constants (Eqs. 2, 8, 9)

q:

solid-phase concentration of the adsorbed material per unit mass of particle

qm :

the adsorption capacity of the adsorbent or the maximum value of q

q0 :

value of q at equilibrium with feed concentration C0

q:

average concentration within the particle

q*:

value of q at the interface

R:

rate of interfacial mass transfer per unit interstitial void volume

rs :

particle radius

t:

time

v:

interstitial velocity or linear velocity of fluid

x:

axial distance along bed

É›:

interparticle void fraction

ɛi :

intraparticle void fraction

ϱ;b :

bed density, mass of packing per unit bed volume

ϱ;p :

particle density

ν:

reduced velocity, ν=vdpD

Author information

Authors and Affiliations

Authors

Editor information

A. Fiechter

Rights and permissions

Reprints and permissions

Copyright information

© 1982 Springer-Verlag

About this paper

Cite this paper

Yang, CM., Tsao, G.T. (1982). Packed-bed adsorption theories and their applications to affinity chromatography. In: Fiechter, A. (eds) Chromatography. Advances in Biochemical Engineering, vol 25. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3540118292_1

Download citation

  • DOI: https://doi.org/10.1007/3540118292_1

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-11829-9

  • Online ISBN: 978-3-540-39495-2

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics