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MR Spectroscopic Imaging

  • Chapter
Brain Tumor Imaging

Part of the book series: Medical Radiology ((Med Radiol Diagn Imaging))

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Abstract

MR spectroscopy (MRS) allows the noninvasive measurement of the concentrations from selected metabolites in vivo. Till now, MR spectroscopy is applied for specific purposes in brain tumor diagnostics. The metabolic profile of a brain tumor not only characterizes tumor entity, but it may also be crucial for prognosis and for therapeutic decisions. In the last decades, it has become evident that molecular genetic markers of a brain tumor may be prognostic or even predictive for a specific therapy (Weller et al. 2009; Reifenberger et al. 2012). Therefore, therapy of brain tumors is becoming increasingly complex, and histopathological features should not be the only aspect of establishing therapeutic decisions in the future.

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Abbreviations

ATRT:

Atypical teratoid rhabdoid tumor

BCNU:

Bis-chloroethylnitrosourea (carmustine)

GBM:

Glioblastoma multiforme

HIF1α:

Hypoxia-inducible factor 1-alpha

PFS:

Progression-free survival

PNET:

Primitive neuroectodermal tumor

PRESS:

Point resolved spectroscopy

rGBM:

Recurrent glioblastoma multiforme

STEAM:

Stimulated echo acquisition mode

T:

Tesla

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Authors and Affiliations

  1. Neuroradiology, Clinic of Rheinische, Friedrich-Wilhelms-University, Sigmund-Freud Straße 6, 53127, Bonn, Germany

    Elke Hattingen

  2. Neuroradiology, Goethe University Frankfurt, Schleusenweg 2-16, 60528, Frankfurt/Main, Germany

    Ulrich Pilatus

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  1. Elke Hattingen
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  2. Ulrich Pilatus
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Correspondence to Elke Hattingen or Ulrich Pilatus .

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Editors and Affiliations

  1. Neuroradiology, Dept. of Radiol., University Hospital Bonn, Bonn, Germany

    Elke Hattingen

  2. Neuroradiology, Goethe University, Hospital Frankfurt, Frankfurt/Main, Germany

    Ulrich Pilatus

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Hattingen, E., Pilatus, U. (2014). MR Spectroscopic Imaging. In: Hattingen, E., Pilatus, U. (eds) Brain Tumor Imaging. Medical Radiology(). Springer, Berlin, Heidelberg. https://doi.org/10.1007/174_2014_1031

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  • DOI: https://doi.org/10.1007/174_2014_1031

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  • Print ISBN: 978-3-642-45039-6

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