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Electrochemical Biosensors for Detecting Microbial Toxins by Graphene-Based Nanocomposites

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Abstract

It is important to develop methods to determine microbial toxins at trace levels since these toxins are ubiquitous commonly found in water and foods, and pose potential threats to both human health and ecosystem safety. Taking the advantages of ultrahigh electron-transfer capability, extra-large surface area and easily functionalized ability, the graphene-based nanocomposites have been employed to fabricate electrochemical biosensors including immunosensors and aptasensors for detecting microbial toxins with high sensitivity. The specificity and selectivity of the electrochemical biosensors for targeting toxins can be achieved by combining graphene nanocomposites with antibodies and/or aptamers. The graphene nanocomposite-based electrochemical biosensors could become a promising technique in the detection of microbial toxins for public and environmental health protection.

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Authors and Affiliations

  1. State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022, China

    Girma Selale Geleta, Zhen Zhao & Zhenxin Wang

  2. University of Chinese Academy of Sciences, Beijing, 100039, China

    Girma Selale Geleta & Zhen Zhao

Authors
  1. Girma Selale Geleta
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  2. Zhen Zhao
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  3. Zhenxin Wang
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Correspondence to Zhenxin Wang.

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Geleta, G.S., Zhao, Z. & Wang, Z. Electrochemical Biosensors for Detecting Microbial Toxins by Graphene-Based Nanocomposites. J. Anal. Test. 2, 20–25 (2018). https://doi.org/10.1007/s41664-018-0051-y

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  • DOI: https://doi.org/10.1007/s41664-018-0051-y

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