Abstract
Primary lung cancer is the most frequently diagnosed malignancy in the world and the leading cause of death from cancer [1]. When the initial diagnosis is made, most cases are inoperable or the patients’ condition does not permit surgical interventions [2]. For patients with inoperable lung cancer, percutaneous radio-frequency thermal ablation (RFA) under CT guidance represents an alternative and minimally invasive treatment. It can also be applied in combination with radiation therapy and chemotherapy. We report three cases treated by percutaneous CT-guided RF ablation, from which two had post-operative recurrent tumor and one was inoperable.
Similar content being viewed by others
References
Smith R, Glynn T (2000) Epidemiology of lung cancer. Radiol Clin North Am 38:453–470
Park B, Louie O, Attorki N (2000) Staging and the surgical management of lung cancer. Radiol Clin North Am 38:545–561
Siperstein A, Gotomirski A (2000) History and technological aspects of radio-frequency thermo-ablation. Cancer J 6:S293–S301
Livraghi T, Solbiati L, Franca-Meloni M, Scott-Gazelle G, Halpern E, Nahum-Goldberg S (2003) Treatment of focal liver tumors with percutaneous radio-frequency ablation: complications encountered in a multicenter study. Radiology 226:441–451
Dupuy D, Nahum Goldberg S (2001) Image-guided radio-frequency ablation. Part II: challenges and opportunities. J Vasc Interv Radiol 12:1135–1148
McGahan JP, Dodd GD III (2001) Radio-frequency ablation of the liver: current status. Am J Roentgenol 176:3–16
Gervais DA, McGovern FJ, Wood BJ, Goldberg SN, McDougal WS, Mueller PR (2000) Radio-frequency ablation of renal cell carcinoma: early clinical experience. Radiology 217:665–721
Lee JM, Kim SW, Chung GH, Lee SY, Han YM, Kim CS (2003) Open radio-frequency thermal ablation of renal VX2 tumors in a rabbit model using a cooled-tip electrode: feasibility, safety and effectiveness. Eur Radiol 13:1324–1332
Merkle EM, Shonk JR, Zheng L, Duerk JL, Lewin JS (2001) MR imaging-guided radio-frequency thermal ablation in the porcine brain at 0.2 T. Eur Radiol 11:884–892
Erikson JK, Rosenthal DI, Zaleske DJ, Gebhardt MC, Cates JM (2001) Primary treatment of chondroblastoma with percutaneous radio-frequency heat ablation: report of three cases. Radiology 221:463–468
Woertler K, Vestring T, Boettner F, Winkelmann W, Heindel W, Linder N (2001) Osteoid osteoma: CT-guided percutaneous radio-frequency ablation and follow-up in 47 patients. J Vasc Interv Radiol 12:717–722
Dupuy D, Zagoria RJ, Akerley W, Mayo-Smith WW, Kavanagh PV, Safran H (2000) Percutaneous radio-frequency ablation of malignancies in the lung. AJR 174:57–59
Sewell PE, Vance RB, Wang YD (2000) Assessing radio-frequency ablation of non-small cell lung cancer with positron emission tomography (PET). Radiology 217:334
Glenn DW, Clark W, Morris DL, King J, Zhao J, Clingan P (2001) Percutaneous radio-frequency ablation of colorectal pulmonary metastases. In: RSNA Conference 2001, 25–30 November, Chicago
Dupuy D, Mayo-Smith W, Abbott G, DiPetrillo T (2002) Clinical applications of radio-frequency tumor ablation in the thorax. Radiographics 22:S259–S269
Lee JM, Youk KK, Kim YK, Han YM, Chung HC, Lee SY, Kim CS (2003) Experimental: radio-frequency thermal ablation with hypertonic saline solution injection of the lung: ex vivo and in vivo feasibility studies. Spinger, Berlin Heidelberg New York
Highland AM, Mack P, Breen DJ (2002) Radio-frequency thermal ablation of metastatic lung nodule. Eur Radiol 12 (Suppl 3):S166–S170
Miao Y, Ni Y, Yu J, Zhang H, Baert A, Marchal G (2001) An ex vivo study on radio-frequency tissue ablation: increased lesion size by using an “expandable-wet” electrode. Eur Radiol 11:1841–1847
Goldberg SN, Hahn PF, Tanabe KK et al. (1998) Percutaneous radio-frequency tissue ablation: Does perfusion-mediated tissue cooling limit coagulation necrosis? J Vasc Interv Radiol 9:101–105
Steinke K, Habicht J, Thomsen S, Soler M, Jacob A (2002) CT-guided radio-frequency ablation of a pulmonary metastasis followed by surgical resection. Cardiovasc Intervent Radiol 25:544–546
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Thanos, L., Mylona, S., Pomoni, M. et al. Primary lung cancer: treatment with radio-frequency thermal ablation. Eur Radiol 14, 897–901 (2004). https://doi.org/10.1007/s00330-003-2189-9
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00330-003-2189-9