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Measurement of Regional Tissue Bed Venous Weighted Oximetric Trends During Exercise by Near Infrared Spectroscopy

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Abstract

Background

Cardiopulmonary exercise testing (CPET) is limited to children able to tolerate the equipment. Modification of instrumentation to reduce invasiveness will open CPET to a wider population. Near Infrared Spectroscopy (NIRS) devices measure regional oxyhemoglobin saturation (rSO2). We aim to predict anaerobic threshold (AT) during CPET using multiorgan NIRS monitoring.

Methods and Results

Nineteen subjects were recruited. NIRS probes were placed on the forehead, para vertebral space, vastus lateralis, and deltoid muscle (rSO2 C, rSO2 R, rSO2 L and rSO2 A). rSO2 was recorded at six second intervals at rest, exercise, and through a five minute recovery period. The AT was computed using the v-slope method. AT was also predicted using NIRS data by identifying the inflection point of the rSO2 trends for all the four sites. AT can be estimated by the point of slope change of rSO2 R, rSO2 C and the four-site composite measure.

Conclusions

Multisite NIRS monitoring of visceral organs is a potential predictor of AT. This allows for monitoring in all forms of exercise over a wide age range.

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Acknowledgments

We would like to acknowledge the invaluable logistical support and coordination of this research provided by Mary M. Krolikowski, RN, MSN.

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Authors and Affiliations

  1. Department of Pediatrics, Division of Cardiology and Critical Care, Medical college of Wisconsin, Milwaukee, USA

    Rohit P. Rao

  2. Department of Pediatrics, Division of Cardiology, Medical college of Wisconsin, Milwaukee, USA

    Peter C. Frommelt & Stuart Berger

  3. Department of Anesthesia, Division of Pediatric Anesthesia, Medical college of Wisconsin, Milwaukee, USA

    George M. Hoffman

  4. Herma Heart Center, Children’s Hospital of Wisconsin, MS 713, Milwaukee, WI, 53072, USA

    Rohit P. Rao & Michael J. Danduran

  5. Department of Pediatrics, Division of Critical Care, Medical college of Wisconsin, Milwaukee, USA

    Nancy S. Ghanayem

  6. Quantitative Health Sciences Department, Medical College of Wisconsin, Milwaukee, USA

    Pippa M. Simpson & Ke Yan

Authors
  1. Rohit P. Rao
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  2. Michael J. Danduran
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  3. Peter C. Frommelt
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  4. Nancy S. Ghanayem
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  5. Stuart Berger
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  6. Pippa M. Simpson
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  7. Ke Yan
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  8. George M. Hoffman
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Corresponding author

Correspondence to Rohit P. Rao.

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Grant Support

Pilot Innovative Research (PIR) Award, Children’s Research Institute, Children’s Health System, Milwaukee, WI.

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Rao, R.P., Danduran, M.J., Frommelt, P.C. et al. Measurement of Regional Tissue Bed Venous Weighted Oximetric Trends During Exercise by Near Infrared Spectroscopy. Pediatr Cardiol 30, 465–471 (2009). https://doi.org/10.1007/s00246-009-9393-6

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  • DOI: https://doi.org/10.1007/s00246-009-9393-6

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