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In vitro and in vivo inhibitory action of 2-amino-4,6-dichloropyrimidine on polio and herpes virus

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Résumé

La 2-amino-4,6-dichloropyrimidine (Py 11) est capable d'inhiber la réplication du poliovirus et du virusHerpes simplex dans des milieux de culture complète, à condition que la mercaptoéthanolamine y soit aussi présente. Les combinaisons des deux composés sont actives, in vivo contre ≪l'herpes cornealis≫ du lapin.

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Literatur

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Authors and Affiliations

  1. Istituto di Microbiologia II dell'Università, Via G. T. Porcell 12, Cagliari, Italy

    M. A. Marcialis, O. Flore, A. Firinu, P. La Colla & A. Garzia

Authors
  1. M. A. Marcialis
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  2. O. Flore
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  3. A. Firinu
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  4. P. La Colla
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  5. A. Garzia
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  6. B. Loddo
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Additional information

This work has been supported by a Grant of the Consiglio Nazionale delle Ricerche, Roma.

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Marcialis, M.A., Flore, O., Firinu, A. et al. In vitro and in vivo inhibitory action of 2-amino-4,6-dichloropyrimidine on polio and herpes virus. Experientia 30, 1272–1273 (1974). https://doi.org/10.1007/BF01945180

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  • DOI: https://doi.org/10.1007/BF01945180

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