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Handbook of Dietary Phytochemicals pp 1–40Cite as

Caffeoylquinic Acids

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Abstract

Caffeoylquinic acids (CQAs) are a large family of phenylpropanoids (chemically esters) found in large amounts in coffee beans but typically occur in many other edible plants, and as such, they belong to the most widespread polyphenols in plant kingdom. They are also associated with significant health benefits resulting from the consumption of beverages such as coffee and yerba maté as well as some popular vegetables such as globe artichoke or endive. Also, many medicinal herbs owe their properties to their CQA content. Here, we focused on the importance of these compounds for functional properties of healthy foodstuff, summarizing such well-studied aspects as bioavailability, in vitro and in vivo pharmacological effects, and potential for lifestyle disease prevention and management. The chemical diversity and analytical approaches are also outlined.

From the literature review, it is concluded that CQAs count as the most essential healthy constituents of various foods and beverages and should be included in characterization of edible consumer products. At the same time, one should remember that caution is necessary in claiming unfounded properties to cure diseases. Therefore, more research is necessary, especially on human subjects, as well as further development of affordable and reliable analytical methods in an ultimate goal to understand their distribution, diversity, and function.

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  1. Department of Pharmaceutical Biology, Wroclaw Medical University, Wroclaw, Poland

    Dorota Woźniak, Izabela Nawrot-Hadzik, Weronika Kozłowska, Sylwester Ślusarczyk & Adam Matkowski

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  1. Institute of Chinese Medical Sciences, University of Macau Institute of Chinese Medical Sciences, Macau, Macao

    Jianbo Xiao

  2. School of Pharmacy & Biomolecular Sci., Liverpool John Moores University School of Pharmacy & Biomolecular Sci., Liverpool, UK

    Satyajit D. Sarker

  3. Faculty of Pharmaceutical Sciences, Tokushima Bunri University Faculty of Pharmaceutical Sciences, Tokushima, Japan

    Yoshinori Asakawa

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Woźniak, D., Nawrot-Hadzik, I., Kozłowska, W., Ślusarczyk, S., Matkowski, A. (2020). Caffeoylquinic Acids. In: Xiao, J., Sarker, S., Asakawa, Y. (eds) Handbook of Dietary Phytochemicals. Springer, Singapore. https://doi.org/10.1007/978-981-13-1745-3_23-1

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