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Tumors of the Skin

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Atlas of Skin Disorders

Abstract

Skin tumor is the most intriguing topic for the clinicians. This chapter covers a wide range of issues and provides with informative clues and tips associated with clinical features and pathological presentations and keeps pace with the latest development in molecular biology and immunohistochemistry to assist the readers in the establishment of accurate diagnosis. These following disorders are elaborately selected and arranged from a histopathological perspective.

(1) Tumors of the epidermis include epidermal nevus, unilateral epidermal nevus, epidermal nevus syndrome, seborrheic keratosis, seborrheic keratosis and pityrosporum ovale, large cell acanthoma, giant cutaneous horn, multiple Bowen’s disease, extramammary Paget’s disease, eruptive keratoacanthoma, superficial basal cell carcinoma, fibroepithelioma of Pinkus, Marjolin’s ulcer of squamous cell carcinoma secondary to radiation, cutaneous clear cell squamous cell carcinoma, and milia en plaque.

(2) The list of cutaneous appendage proliferations and tumors present cases with eruptive vellus hair cysts, nevus comedonicus, dilated pore, inverted follicular keratosis, infundibulocystic basal cell carcinoma, trichofolliculoma, trichoepithelioma, bullous pilomatricoma, areolar sebaceous hyperplasia, nevus sebaceous with apocrine cystadenoma, linear nevus sebaceous syndrome, apocrine hidrocystoma, eccrine angiomatous hamartoma, syringocystadenoma papilliferum, eruptive milium-like syringoma, segmental multiple eccrine spiradenomas, clear cell hidradenoma, malignant eccrine poroma, or microcystic adnexal carcinoma.

(3) The category of cutaneous soft tissue proliferations and neoplasms introduces acquired digital fibrokeratoma, epithelioid cell histiocytoma, multiple eruptive dermatofibromas, intradermal nodular fasciitis, dermatofibrosarcoma protuberan, epithelioid sarcoma, superficial angiomyxoma, multicentric reticulohistiocytosis, Letterer-Siwe disease, cutaneous Rosai-Dorfman disease, phakomatosis pigmentovascularis, angiokeratoma corporis diffusum, angiokeratoma of Fordyce, angioma serpiginosum, reactive angioendotheliomatosis, epithelioid hemangioma, tufted angioma, verrucous hemangioma, targetoid hemosiderotic hemangioma, microvenular hemangioma, glomus tumor, spindle cell hemangioma, Kaposiform hemangioendothelioma, classic Kaposi’s sarcoma, cutaneous angiosarcoma, acquired progressive lymphangioma, lymphangioma, nevus lipomatosus superficialis, encephalocraniocutaneous lipomatosis, madelung disease, multiple leiomyoma, cutaneous leiomyosarcoma, subungual exostosis, and cutaneous endometriosis.

(4) Palisaded encapsulated neuroma, schwannoma, and cutaneous Merkel cell carcinoma belong to neural tumors.

(5) Melanocytic nevi and neoplasms include agminated Spitz nevus, subungual melanoma, fatal leptomeningeal melanoma in neurocutaneous melanosis, as well as rare forms of cutaneous melanoma.

(6) Cutaneous lymphoid proliferations and leukemic infiltration consist of cutaneous pseudolymphoma, Jessner’s lymphocytic infiltration of the skin Jessner, Ketron-Goodman disease, mycosis fungoides, erythrodermic cutaneous T-cell lymphoma, subcutaneous panniculitis-like T-cell lymphoma, hydroa vacciniforme-like lymphoma, extranodal NK-/T-cell lymphoma, primary cutaneous B-cell lymphoma, maculopapular cutaneous mastocytosis, diffuse cutaneous mastocytosis, mastocytoma, cutaneous plasmacytoma, polycythemia vera, leukemia cutis, and so on.

(7) Cutaneous metastases include cutaneous metastasis for lung cancer, cutaneous metastasis of gastrointestinal malignancy, Sister Mary Joseph’s nodule, and carcinoma en cuirasse.

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Author information

Authors and Affiliations

  1. Department of Dermatology, Liaoning General Hospital of Nuclear Industry, Xingcheng, China

    Yong-Hang Zhu

  2. Department of Dermatology, The First People’s Hospital of Yunnan, Kunming, China

    Gui-Xiu Zhang

  3. Department of Dermatology, Tianjin Academy of Traditional Chinese Medicine Affiliated Hospital, Tianjin, China

    Li Tang

  4. Department of Dermatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China

    Xiao-Jie Li M.D., Wen-Yuan Zhu M.D., Mai-Hua Hou M.D., Yan Lu M.D. & Jing Fang

  5. Department of Dermatology, The Third Affiliated Hospital of Suzhou University, Changzhou, China

    Ru-Zhi Zhang M.D.

  6. Nanjing Medical University, Nanjing, China

    Ming-Yu Xia M.D.

  7. Institute of Dermatology of Chinese PLA, Xijing Hospital, The Fourth Military Medical University, Xi’an, China

    Lei Wang & Gang Wang M.D.

  8. Department of Dermatology, Affiliated Hospital of Chengde Medical College, Chengde, China

    Ying Ren

  9. Department of Dermatology, The People’s Hospital of Shanwei, Shanwei, Guangdong, China

    Hui-Pu Zhou

  10. Department of Dermatology, China-Japan Friendship Hospital, Beijing, China

    De-Hai Pan, Pei-Hua Song & Guang-Cai Xiang

  11. Department of Dermatology, The First Hospital of Hangzhou, Hangzhou, China

    Li-Jian Xiang

  12. Department of Dermatology, Skin Disease Prevention Center, Jingmen, Hubei Province, China

    Jin-Fa Su

  13. Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China

    Hui Zhang

  14. Department of Dermatology, Peking University People’s Hospital, Beijing, China

    Juan Du M.D., Jiang Jin, Xiao-Bing Pi & Guang-Ren Liu

  15. Department of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

    Dong-Lai Ma M.D., Lan Yang, Jie Yan, Yan Yan, Hong-Zhong Jin M.D., Jia-Bi Wang M.D., Jian-Ying Zeng & Bin Su

  16. Department of Dermatology, Fujian Dongshan County Hospital, Fujian, China

    Shu-Qin Lv

  17. Department of Dermatology and Venereology, Southwest Hospital, Third Military Medical University, Chongqing, China

    Xi-Chuan Yang M.D., Shao-Wen Peng & Zhi-Fang Zhai M.D.

  18. Department of Dermatology and Venereology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China

    Jie Gao M.D.

  19. Department of Dermatology, General Hospital of Guangzhou Military Command of PLA, Guangzhou, China

    Ting Lin

  20. Department of Dermatology, Dongguan Donghua Hospital, Guangzhou, China

    Zhi-Ping Sun

  21. Department of Dermatology, Xijing Hospital, Institute of PLA Dermatology, The Fourth Military Medical University, Xi’an, China

    Li Yang

  22. Department of Dermatology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China

    Cheng Tan M.D.

  23. Department of Dermatology, The Affiliated Hospital of Zunyi Medical College, Zunyi, China

    Ji-Ling Zhang

  24. Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

    Yan Wu M.D.

  25. Department of Dermatology, Air Force General Hospital, PLA, Beijing, China

    Hong Zhang

  26. Department of Plastic Surgery, Tianjin Changzheng Hospital, Tianjin, China

    Gang Liu

  27. Department of Dermatology, Xian Yang Central Hospital, Xian Yang, China

    Bao-Chun Li

  28. Department of Dermatology, Affiliated Hospital of Guangzhou Medical University, Guangzhou, China

    Shun-Fan Li M.D.

  29. Department of Dermatology, Tianjin Changzheng Hospital, Tianjin, China

    Yang Guan & Shu-Fang Qiao M.D.

  30. Department of Pathology, Tianjin Changzheng Hospital, Tianjin, China

    Yin Xiao M.D.

  31. Institute of Dermatology and STD of Fujian Province, Fuzhou, China

    Shan Tang

  32. Department of Dermatology, Peking University First Hospital, Beijing, China

    Zhong Xie & Xue-Jun Zhu M.D.

  33. Department of Dermatology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

    Feng Wu & Hong-Hao Jiang

  34. Panyu Chronic Disease Hospital, Guangzhou, China

    Xiao-Mei Zhang

  35. Institute of Dermatology, Chinese Academy of Medical Sciences, Nanjing, China

    Jian-Fang Sun M.D.

  36. Department of Dermatology, Beijing Hospital, Beijing, China

    Wen-Hai Li & Jian-Min Chang M.D.

  37. Department of Dermatology, The Second Affiliated Hospital, Kunming Medical College, Kunming, China

    Mei Cai

  38. Department of Dermatology, The Second Hospital, Shandong University, Jinan, China

    Chun-Mei Zhang

  39. Department of Dermatology, Nantong Rich Hospital, Fourth Clinical College of Yangzhou University, Nantong, China

    Xian Zhang

  40. Department of Dermatology, The People’s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, China

    Xiong-Ming Pu M.D. & Yi-Ming Xu

  41. Department of Dermatology, Second Affiliated Hospital of Sun Yat-Sen University, GuangZhou, China

    Xiao-Jun Zhu

  42. Department of Medical Cosmetology, Heping Hospital, The Changzhi Medical College, Changzhi, China

    Cun-Cai Zhou

  43. Department of Dermatology, Datong Fifth Hospital, Datong, China

    Jian-Ping Liang

  44. Department of Surgery, Qianan People’s Hospital, Qianan, China

    Zhi-Xin Song M.D.

  45. Department of Dermatology, Cangzhou People’s Hospital, Cangzhou, China

    Jun Peng

  46. Department of Dermatology, The Third Affiliated Hospital of Souzhou University, Changzhou, China

    Chun-Xing Xu

  47. Department of Pathology, Lanzhou General Hospital of Lanzhou Military Command, Lanzhou, China

    Chuan-Ping Xing

  48. Department of Dermatology, Chaoyang Dafeng Hospital of Shantou, Shantou, China

    Dian-Ying Zhuang

  49. Department of Dermatology, Shenzhen Center for Chronic Disease Control, Shenzhen, China

    Min Huang

  50. Department of Dermatology, Qilu Hospital, Shandong University, Jinan, China

    Chun-Yang Li M.D.

  51. Department of Dermatology, Guang’anmen Hospital, China Academy of Traditional Chinese Medicine, Beijing, China

    Bing-Nan Cui M.D.

  52. Department of Dermatology, Tangshan Union Hospital, Tangshan, China

    Xiao-Yan Guo

  53. Department of Dermatology, Institute of Dermatology and Hospital for Skin Diseases, Chinese Academy of Medical Sciences & Peking Union Medical Collage, Nanjing, China

    Tong Lin M.D.

  54. Department of Dermatology, Huashan Hospital of Fudan University, Shanghai, China

    Bing-Sen Qiu M.D.

  55. Department of Dermatology, Second Hospital of Xi’an Jiaotong University, Xi’an, China

    Sheng-Shun Tan M.D.

  56. Institute of Dermatology, Peking Union Medical College, Chinese Academy of Medical Science, Nanjing, China

    Yi-Qun Jiang M.D.

  57. Department of Dermatology, The Second Affiliated Hospital of Zhejiang Medical University, Hangzhou, China

    Min Zheng M.D.

  58. Department of Dermatology, Affiliated Hospital of Children Capital Institute of Pediatrics, Beijing, China

    Jin Hu

  59. Department of Dermatology, Hubei Jianghan Oilfield Central Hospital, Qianjiang, China

    Guang-He Yang & An Liu

  60. Department of Hematology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China

    Zheng Ge M.D.

  61. Department of Dermatology, Tianjin Gong’an Hospital, Tianjin, China

    Jing Chen

  62. Department of Dermatology, People’s Hospital of Beijing University, Beijing, China

    Lin Cai

  63. Department of Dermatology, West China Hospital, Sichuan University, Chengdu, Sichuan, China

    Sheng Wang M.D.

  64. Department of Dermatology and Venereology, West China Hospital of Sichuan University, Chengdu, China

    Xian Jiang

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  1. Yong-Hang Zhu
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  2. Gui-Xiu Zhang
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  18. Shu-Qin Lv
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  32. Lan Yang
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  38. Shan Tang
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  39. Zhong Xie
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  40. Feng Wu
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  43. Wen-Hai Li
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  44. Mei Cai
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  47. Gang Wang M.D.
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  48. Hong-Hao Jiang
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  49. Jiang Jin
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  50. Xiong-Ming Pu M.D.
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  51. Jian-Min Chang M.D.
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  52. Yan Lu M.D.
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  53. Xiao-Jun Zhu
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  54. Cun-Cai Zhou
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  56. Jian-Ping Liang
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  59. Jun Peng
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  81. Min Zheng M.D.
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  82. Jin Hu
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  83. Guang-He Yang
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  84. Zheng Ge M.D.
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  86. Lin Cai
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  87. Sheng Wang M.D.
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  88. An Liu
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  89. Xian Jiang
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Corresponding author

Correspondence to Cheng Tan M.D. .

Editor information

Editors and Affiliations

  1. Department of Dermatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China

    Wen-Yuan Zhu

  2. Department of Dermatology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China

    Cheng Tan

  3. Department of Dermatology, The Third Affiliated Hospital of Suzhou University, Changzhou, China

    Ru-zhi Zhang

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© 2018 Springer Nature Singapore Pte Ltd. and People's Military Medical Press

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Zhu, YH. et al. (2018). Tumors of the Skin. In: Zhu, WY., Tan, C., Zhang, Rz. (eds) Atlas of Skin Disorders. Springer, Singapore. https://doi.org/10.1007/978-981-10-8037-1_27

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  • DOI: https://doi.org/10.1007/978-981-10-8037-1_27

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  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-10-8036-4

  • Online ISBN: 978-981-10-8037-1

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