Introduction
Functionalized aryl fluorides are important motifs because of their widespread application in pharmaceuticals, agrochemicals, materials, and medical diagnosis (positron emission tomography, PET) [1]. As a result, the development of efficient and practical procedures for the construction of aryl C–F bonds has received much attention. Recently, a series of transition metals have been explored for preparing aryl fluorides [2, 3]. Inexpensive metals such as copper have emerged as alternative mediators of C−F bond formation [4]. This section mainly focused on recent advances in copper-mediated/-catalyzed fluorination reactions to construct aryl fluorides. Among these reactions, the fluoride sources could be divided into nucleophilic fluorinating reagents and electrophilic fluorinating reagents (Scheme 1).
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Miao, W., Hu, J. (2019). Copper-Mediated Fluorination for Preparing Aryl Fluorides. In: Hu, J., Umemoto, T. (eds) Fluorination. Synthetic Organofluorine Chemistry. Springer, Singapore. https://doi.org/10.1007/978-981-10-1855-8_63-1
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