Abstract
The existence of discrete 5-HT-containing neurones in the brain stem with extensive ramifications to neuroanatomical regions involved in cardiovascular regulation has been known for more than two decades [1]. Our understanding, however, of the intricate interactions of the 5-HT networks and central autonomic pathways has been rather slow to evolve [2–4]. Thus, despite substantial evidence implicating an important role for central 5-HT neurotransmission in blood pressure regulation, the precise nature of this role remains unclear.
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Mir, A.K., Fozard, J.R. (1990). Central 5-hydroxytryptamine (5-HT) and its effect on the cardiovascular system. In: Saxena, P.R., Wallis, D.I., Wouters, W., Bevan, P. (eds) Cardiovascular Pharmacology of 5-Hydroxytryptamine. Developments in CardioCardiovascular Pharmacology of 5-Hydroxytryptamine, vol 106. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-0479-8_18
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