Abstract
Pilomyxoid astrocytoma (PMA) is a recently described rare tumor which is a variant of pilocytic astrocytoma (PA). It exhibits a more aggressive behavior than PA. Spinal cord PMA has been reported in two articles in the past and none of the reported case had extraneural metastasis. We report on a female child with cervical cord PMA with diffuse leptomeningeal metastasis involving the brain and spinal cord. Two years later she presented with peritoneal carcinomatoses which was consistent with metastatic tumor via a ventriculoperitoneal (VP) shunt. This case confirms the aggressive behavior of PMA and makes clinicians aware of the possibility of extraneural, peritoneal metastasis through a VP shunt.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Declercq H, De Man R, Vanderperre H, De Praetere P, Wilms G (1992) Peritoneal seeding of a cerebral malignant astrocytoma via a ventriculo-peritoneal shunt. JBR-BTR Journal belge de radiologi 75:191–193
Duffner PK, Cohen ME (1981) Extraneural metastases in childhood brain tumors. Ann Neurol 10:261–265
Hoffman HJ, Hendrick EB, Humphreys RP (1976) Metastasis via ventriculoperitoneal shunt in patients with medulloblastoma. J Neurosurg 44:562–566
Komotar RJ, Mocco J, Carson BS, Sughrue ME, Zacharia BE, Sisti AC, Canoll PD, Khandji AG, Tihan T, Burger PC, Bruce JN (2004) Pilomyxoid astrocytoma: a review. MedGenMed 6:42
Komotar RJ, Carson BS, Rao C, Chaffee S, Goldthwaite PT, Tihan T (2005a) Pilomyxoid astrocytoma of the spinal cord: report of three cases. Neurosurgery 56:191
Komotar RJ, Mocco J, Jones JE, Zacharia BE, Tihan T, Feldstein NA, Anderson RC (2005b) Pilomyxoid astrocytoma: diagnosis, prognosis, and management. Neurosurg Focus 18:E7
Mendiratta-Lala M, Kader Ellika S, Gutierrez JA, Patel SC, Jain R (2007) Spinal cord pilomyxoid astrocytoma: an unusual tumor. J Neuroimaging 17:371–374
Pasquier B, Pasquier D, N’Golet A, Panh MH, Couderc P (1980) Extraneural metastases of astrocytomas and glioblastomas: clinicopathological study of two cases and review of literature. Cancer 45:112–125
Schweitzer T, Vince GH, Herbold C, Roosen K, Tonn JC (2001) Extraneural metastases of primary brain tumors. J Neurooncol 53:107–114
Tihan T, Fisher PG, Kepner JL, Godfraind C, McComb RD, Goldthwaite PT, Burger PC (1999) Pediatric astrocytomas with monomorphous pilomyxoid features and a less favorable outcome. J Neuropathol Exp Neurol 58:1061–1068
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2012 Springer Science+Business Media B.V.
About this chapter
Cite this chapter
Arulrajah, S., Huisman, T.A.G.M. (2012). Pilomyxoid Astrocytoma of the Spinal Cord with Cerebrospinal Fluid and Peritoneal Metastasis. In: Hayat, M. (eds) Tumors of the Central Nervous System, Volume 6. Tumors of the Central Nervous System, vol 6. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-2866-0_9
Download citation
DOI: https://doi.org/10.1007/978-94-007-2866-0_9
Published:
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-007-2865-3
Online ISBN: 978-94-007-2866-0
eBook Packages: MedicineMedicine (R0)