Riassunto
La risposta dell’organismo verso la colonizzazione di un tessuto corporeo da parte di un germe patogeno determina l’inizio di un processo fisiopatologico chiamato infezione. L’agente patogeno può essere rappresentato da batteri, virus, funghi, o protozoi. A seconda dello specifico meccanismo fisiopatologico, l’infezione è classificata in acuta, cronica, e cronica con riacutizzazione. L’infezione acuta è caratterizzata dalla presenza di essudato, nel quale le cellule infiltranti sono rappresentate prevalentemente da polimorfonucleati; nell’infezione cronica le cellule infiltranti sono invece costituite da linfociti, monociti e macrofagi, con associata proliferazione di vasi sanguigni, fibrosi e necrosi. Le risposte cellulari e vascolari sono mediate da agenti chimici liberati, attivati, o prodotti in risposta allo stimolo infiammatorio.
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Sollini, M., Dell’Anno, B., Lazzeri, E. (2010). Tecniche diagnostiche per lo studio delle infezioni/flogosi. In: Volterrani, D., Mariani, G., Erba, P.A. (eds) Fondamenti di medicina nucleare. Springer, Milano. https://doi.org/10.1007/978-88-470-1685-9_21
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