Abstract
During the past 15 years, dramatic changes have been made in the treatment of osteosarcoma. The survival rate of patients with osteosarcoma has improved as a result of better adjuvant chemotherapeutic regimens [1–3]. There are many other factors, however, that have been shown to influence the prognosis of this disease, among them the patient’s age, site and size of the lesion, chemotherapeutic regimens, and surgical procedures [4–9]. We recently reviewed all cases of conventional osteosarcoma treated at Chiba Cancer Center, and analyzed the clinical prognostic factors of this disease.
Keywords
- Pulmonary Metastasis
- Preoperative Chemotherapy
- Limb Salvage
- Osteosarcoma Patient
- Clinical Prognostic Factor
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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References
Umeda T, Takada N (1985) The functional evaluation of osteosarcoma patients with limb salvage treatment (in Japanese). Rinsho Seikei Geka 20: 216–226
Rosen G, Caparros B, Huvos AG, et al. (1982) Preoperative chemotherapy for osteogenic sarcoma: Selection of postoperative adjuvant chemotherapy based on the response of the primary tumor to preoperative chemotherapy. Cancer 49: 1221–1230
Winkler K, Beron G, Kotz R, et al. (1984) Neoadjuvant chemotherapy for osteogenic sarcoma: Results of a cooperative German/Austrian study. J Clin Oncol 12: 617–624
Taylor WF, Ivins JC, Unni KK, et al. (1989) Prognostic variables in osteosarcoma: A multi-institutional study. J Natl Cancer Inst 81: 21–30
Bentzen SM, Poulsen HS, Kaae S, et al. (1988) Prognostic factors in osteosarcomas. Cancer 62: 194–202
Delepine N, Delepine G, Jasmin C, et al. (1988) Importance of age and methotrexate dosage: Prognosis in children and young adults with high-grade osteosarcomas. Biomed Pharmacother 42: 257–262
Raymond AK, Chawla SP, Carrasco CH, et al. (1987) Osteosarcoma chemotherapy effects: A prognostic factor. Semin Diagn Pathol 4: 212–236
Takeyama S, Tateishi A (1989) Analysis for treatment of osteosarcoma — Good prognostic factors. J Jpn Orthop Assoc 63: S455
Scranton PE, DeCicco FA, Totten RS, et al. (1975) Prognostic factors in osteosarcoma: A review of 20 years’ experience at the University of Pittsburgh Health Center. Cancer 36: 2179–2191
Takada N, Hodaka E (1979) The treatment of osteosarcoma (in Japanese). Rinsho Seikei Geka 14: 756–764
Umeda T, Takada N, Hodaka E, et al. (1984) Evaluation of severe side effects of high-dose methotrexate in osteosarcoma (in Japanese). Gan to Kagaku Ryoho 11: 285–294
Umeda T, Takada N, Hodaka E, et al. (1986) Toxic effects of cisplatin in the treatment of malignant bone and soft tissue tumors (in Japanese). Gan To Kagaku Ryoho 13: 1857–1861
Takada N, Hodaka E (1979) Radiation therapy of osteosarcomas (in Japanese). Orthop Surg Traumatol 22: 681–691
Umeda T, Takada N, Seki Y (1983) The treatment of osteosarcoma patients developed pulmonary metastases (in Japanese). Rinsyo Seikei Geka 20: 917–927
Jaffe N, Spears R, Eftekhari F, et al. (1987) Pathological fracture in osteosarcoma. Cancer 59: 701–709
Wuisman P, Enneking WF (1990) Prognosis for patients who have osteosarcoma with skip metastasis. J Bone Joint Surg [Am] 72: 60–68
Rosen G, Huvos AG, Marcove R, et al. (1986) Telangiectatic osteosarcoma: Improved survival with combination chemotherapy. Clin Orthop 207: 164–173
Kawano H (1989) Neoadjuvant chemotherapy for osteosarcoma — The value in survival. J Jpn Orthop Assoc 63: S457
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© 1992 Springer Japan
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Umeda, T., Ishii, T., Kitoh, M., Ozawa, T., Takada, N., Tatezaki, Si. (1992). The Evaluation of Clinical Prognostic Factors in Osteosarcomas. In: Uchida, A., Ono, K. (eds) Recent Advances in Musculoskeletal Oncology. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68364-3_27
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DOI: https://doi.org/10.1007/978-4-431-68364-3_27
Publisher Name: Springer, Tokyo
Print ISBN: 978-4-431-68366-7
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