Zusammenfassung
Die Acne inversa, auch Hidradenitis suppurativa genannt, ist eine multifaktorielle, chronisch progrediente Entzündung der Terminalhaarfollikel in den intertriginösen Hautarealen. Die Erkrankung geht mit Abszessbildung, Fisteln und ausgeprägten Vernarbungen einher.
In diesem Kapitel werden zuerst die allgemeinen Aspekte der Acne inversa inguinalis erläutert, d.h. Definition, Epidemiologie, Pathogenese und Prädisposition. Dann folgt eine genaue Beschreibung der klinischen Faktoren, wie das klinische Erscheinungsbild, Komplikationen, Klassifikationen, Differenzialdiagnosen und Diagnostik. Daran schließt sich die Therapie mit stadienadaptierten chirurgischen sowie rekonstruktiven Verfahren an. Abschließend wird die postoperative Nachbehandlung beschrieben.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Literatur
Alikhan A, Lynch PJ, Eisen DB (2009) Hidradenitis suppurativa: A comprehensive review. J Am Acad Dermatol 60:539–561
Altmann S, Fansa H, Schneider W (2004) Axillary hidradenitis suppurativa: A further option for surgical treatment. J Cutan Med Surg 8:6–10
Barth JH, Layton AM, Cunliffe WJ (1996) Endocrine factors in pre- and postmenopausal women with hidradenitis suppurativa. Br J Dermatol 134:1057–1059
Bechara FG, Hartschuh W (2010) Acne inversa. Hautarzt 61:39–46
Brandt A, Milling A, Zouboulis CC (2015) Langwierige Diagnose, hohe Rezidivrate. Hautnah Dermatologie 3(1):6
Breitkopf C, Bockhorst J, Lippold A, Ernst K, Hundeiker M (1995) Pyoderma fistulans significa (Akne inversa) und Rauch-gewohnheiten. Z Hautkr 70:332–334
Breuninger H (2004) Therapie des Pilonidalsinus und der Acne inversa. Hautarzt 55:254–258
Breuninger H, Wienert V (2001) Acne inversa. Dtsch Ärzteblatt 98(A):2889–2892
Canoui-Poitrine F, Revuz JE, Wolkenstein P, Viallette C, Gabison G, Pouget F, Poli F, Faye O, Bastuji-Garin S (2009) Clinical characteristics of a series of 302 French patients with hidradenitis suppurativa, with an analysis of factors associated with disease severity. J Am Acad Dermatol 61:51–57
Cesko E, Korber A, Dissemond J (2009) Smoking and obesity are associated factors in acne inversa: results of a retrospective investigation in 100 patients. Eur J Dermatol 19:490–493
Church JM, Fazio VW, Lavery IC, Oakley JR, Milsom JW (1993) The differential diagnosis and comorbidity of HP and perianal Crohn’s disease – a further support to this association. Int J Colorectal Dis 8:117–119
Constantinou C, Widom K, Desantis J, Obmann M (2008) Hidradenitis suppurativa complicated by squamous cell carcinoma. Am Surg 74:1177–1181
Edlich RF, Silloway KA, Rodeheaver GT, Cooper PH (1986) Epidemiology, pathology, and treatment of axillary hidradenitis suppurativa. J Emerg Med 4:369–378
Ellis LZ (2011) Hidradenitis suppurativa: Surgical and other management techniques. Dermatol Surg 38(4):517–536
Fimmel S, Zouboulis CC (2010) Comorbidities of hidradenitis suppurativa (acne inversa). Dermatoendocrinol 2:9–16
Fitzsimmons JS, Guilbert PR, Fitzsimmons EM (1985) Evidence of genetic factors in hidradenitis suppurativa. Br J Dermatol 113:1–8
Gregor BE et al (2015) Hidradenitis suppurativa: Epidemiology and scope of the problem. J Am Acad Dermatol 73:4–7
Haußler A et al (2005) Acne inversa: Untersuchung von Einflussgrößen auf Entstehung und Verlauf des Krankheitsbildes (Poster). J Dtsch Dermatol Ges 3:179–180
Herrmann A, Preusser KP, Marsch WC (2000) Die Acne inversa (Hidradenitis suppurativa): Frühzeitig erkennen und kurativ operieren. Chirurg 71:1395–1400
Hurley HJ (1996) Axillary hyperhidrosis, apocrine bromhidrosis, hidradenitis suppurativa and familial benign pemphigus. Surgical approach. In: Roenigk RK, Roenigk HH Jr (Hrsg) Dermatologic Surgery. Principles and Practice, 2. Aufl. New York, S 623–645
Jansen T, Plewig G (1998) Acne inversa. Int J Dermatol 37:96–100
Jansen T, Plewig G (2000) What’s new in acne inversa (alias hidradenitis suppurativa)? J Eur Acad Dermatol Venereol 14:342–343
Jansen T et al (2001) Acne inversa (alias hidradenitis suppurativa). J Eur Acad Dermatol Venereol 15:532–540
Jansen T et al (2003) Acne inversa. In: Kerl H, Garbe C, Cerroni L, Wolff HH (Hrsg) Histopathologie der Haut. Springer, Berlin, S 306–307
Jansen T et al (2005) Klinische Formen der Akne. Hautarzt 56:1018–1026
Jemec GB (1988a) Hidradenitis suppurativa. J Cutan Med Surg 7:47–56
Jemec GB (1988b) The sympathology of hidradenitis suppurativa in women. Br J Dermatol 119:345–350
Jemec GB, Heidenheim M, Nielsen NH (1996) The prevalence of hidradenitis suppurativa and its potential precursor lesions. J Am Acad Dermatol 35:191–194
Kurzen H et al (2000) Surgical treatment of Acne inversa at the University of Heidelberg. Int J Coloproct 22:76–80
Kurzen H, Kurokawa I, Jemec GB, Emtestam L, Sellheyer K, Giamarellos-Bourboulis EJ, Nagy I, Bechara FG, Sartorius K, Lapins J, Krahl D, Altmeyer P, Revuz J, Zouboulis CC (2008) What causes hidradenitis suppurativa? Exp Dermatol 17:455–472
von Laffert M, Helmbold P, Wohlrab J, Fiedler E, Stadie V, Marsch WC (2010) Hidradenitis suppurativa (acne inversa): early inflammatory events at terminal follicles and at interfollicular epidermis. Exp Dermatol 19:533–537
Lam J, Krakowski AC, Friedlander SF (2007) Hidradenitis suppurativa (acne inversa): management of a recalcitrant disease. Pediatr Dermatol 24:465–473
Lapins J, Jarstrand C, Emtestam L (1999) Coagulase-negative staphylococci are the most common bacteria found in cultures from the deep portions of hidradenitis suppurativa lesions, as obtained by carbon dioxide laser surgery. Br J Dermatol 140:90–95
Meixner D et al (2008) Acne inversa. J Dtsch Dermatol Ges 6:189–197
Mengesha YM, Holcombe TC, Hansen RC (1999) hidradenitis suppurativa: two case reports and review of the literature. Pediatr Dermatol 16:292–296
Palmer RA, Keefe M (2001) Early-onset hidradenitis suppurativa. Clin Exp Dermatol 26:501–503
Pillsbury DM et al (1956) Bacterial infections of the skin. In: Pillsbury DM (Hrsg) Dermatology, 1. Aufl. Philadelphia, S 482–489
Plewig G (2003) Acne inversa, Acne keloidalis nuchae, abszedierende Follikulitis der Kopfhaut: Ein verbindendes Konzept. In: Plewig G, Prinz J (Hrsg) Fortschritte der praktischen Dermatologie und Venerologie, Bd. 18. Springer, Berlin, S 192–203
Plewig G, Kligman AM (2005) Acne and Rosacea, 3. Aufl. Springer, Berlin, S 309–314
Plewig G, Steger M (1989) Acne inversa (alias acne triad, acne tetrad or hidradenitis suppurativa). In: Marks R, Plewig G (Hrsg) Acne and related disorders. Martin Dunitz, London, S 345–357
Poli F, Wolkenstein P, Revuz J (2010) Back and face involvement in hidradenitis suppurativa. Dermatology 221:137–141
van Rappard DC et al (2011) Mild to moderate hidradenitis suppurativa treated with local excision and primary closure. J Eur Acad Dermatol Venereol (Epub ahead of print)
Revuz JE, Canoui-Poitrine F, Wolkenstein P, Viallette C, Gabison G, Pouget F, Poli F, Faye O, Roujeau JC, Bonnelye G, Grob JJ, Bastuji-Garin S (2008) Prevalence and factors associated with hidradenitis suppurativa: results from two case-control studies. J Am Acad Dermatol 5:596–601
Rompel R, Petres J (2000) Long-term results of wide surgical excision in 106 patients with hidradenitis suppurativa. Dermatol Surg 26:638–643
Sellheyer K, Krahl D (2005) ‘‘Hidradenitis suppurativa’’ is acne inversa! An appeal to (finally) abandon a misnomer. Int J Dermatol 44:535–540
Sellheyer K, Krahl D (2008) What causes acne inversa (or hidradenitis suppurativa)? – The debate continues. J Cutan Pathol 35:701–703
Shelley WB, Cahn MM (1955) Apocrine sweat retention in man. IV. The foam cell reaction to the escape of apocrine sweat into the dermis. J Invest Dermatol 25(3):169–173
Weyandt G (2005) Operative Therapie der Acne inversa. Hautarzt 56:1033–1039
Wolk K, Warszawska K, Hoeflich C, Witte E, Schneider-Burrus S, Witte K, Kunz S, Buss A, Roewert HJ, Krause M, Lukowsky A, Volk HD, Sterry W, Sabat R (2011) Deficiency of IL-22 contributes to a chronic inflammatory disease: pathogenetic mechanisms in acne inversa. J Immunol 186:1228–1239
Wolkenstein P, Loundou A, Barrau K, Auquier P, Revuz J (2007) Quality of Life Group of the French Society of Dermatology. Quality of life impairment in hidradenitis suppurativa: a study of 61 cases. J Am Acad Dermatol 56:621–623
van der Zee HH, Laman JD, de Ruiter L, Dik WA, Prens EP (2012) Adalimumab (anti-TNF-α) treatment of hidradenitis suppurativa ameliorates skin inflammation: an in situ and ex vivo study. Br J Dermatol 166:298–305
Zouboulis CC, Bechara FG, Fritz K, Kurzen H, Liakou AI, Marsch WC, Milling A, Nast A, Podda M, Taube KM, Wienert V, Winkler T; Deutsche Dermatologische Gesellschaft; Berufsverband Deutscher Dermatologen; Deutsche Gesellschaft für Koloproktologie; Deutsche Gesellschaft für Dermatochirugie; Hidradenitis Suppurativa Foundation; Deutsche Interessengemeinschaft Akne inversa; Deutsche Gesellschaft für Psychosomatische Medizin; European Society of Dermatology and Psychiatry; European Society of Laser Dermatology (2012). ‘‘S1 Leitlinie zur Therapie der Hidradenitis suppurativa/Acne inversa’’ J Dtsch Dermatol Ges. Suppl 5:S1-31. doi: 10.1111/j.1610-0387.2012.08006.x
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2019 Springer-Verlag GmbH Deutschland, ein Teil von Springer Nature
About this chapter
Cite this chapter
Isbir, D., Cedidi, C.C. (2019). Acne inversa inguinalis. In: Mirastschijski, U., Remmel, E. (eds) Intimchirurgie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-57392-1_20
Download citation
DOI: https://doi.org/10.1007/978-3-662-57392-1_20
Published:
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-662-57391-4
Online ISBN: 978-3-662-57392-1
eBook Packages: Medicine (German Language)