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Preliminary Results of a Randomized Study of Intrahepatic Infusion Versus Systemic Infusion of 5-Fluoro-2′ -deoxyuridine for Metastatic Colorectal Carcinoma

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Therapeutic Strategies in Primary and Metastatic Liver Cancer

Part of the book series: Recent Results in Cancer Research ((RECENTCANCER,volume 100))

Abstract

Development of a totally implantable infusion pump produced a renewed interest in hepatic infusional therapy. An initial study employing this pump by Ensminger and associates and the continuous hepatic infusion of 5-fluoro-2′-deoxyuridine (FUdR) observed an 83% response rate [1]. However, further work with this method brought the mean response rate down to 59% (Table 1) [2], which, however, is still higher than the mean response rate obtained with systemic chemotherapy.

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References

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© 1986 Springer-Verlag Berlin · Heidelberg

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Kemeny, N., Daly, J. (1986). Preliminary Results of a Randomized Study of Intrahepatic Infusion Versus Systemic Infusion of 5-Fluoro-2′ -deoxyuridine for Metastatic Colorectal Carcinoma. In: Herfarth, C., Schlag, P., Hohenberger, P. (eds) Therapeutic Strategies in Primary and Metastatic Liver Cancer. Recent Results in Cancer Research, vol 100. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-82635-1_22

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  • DOI: https://doi.org/10.1007/978-3-642-82635-1_22

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-82637-5

  • Online ISBN: 978-3-642-82635-1

  • eBook Packages: Springer Book Archive

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