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Cerebral Ischemia and Dementia pp 185–186Cite as

Linkage Analysis in Italian Pedigrees with Autosomal Dominant Familial Alzheimer’s Disease

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Abstract

Alzheimer’s disease (AD) is an age-related degenerative disorder of the nervous system characterized by the presence of neurofibrillary tangles, neuritic plaques and dystrophic neuntes in susceptible areas of the brain. Over 40% of 80-year-old people are affected [2].

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References

  1. Goate AM, Haynes AR, Owen MJ et al. (1989) Predisposing locus for AD on chromosome 21. Lancet 1:352–353

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Author information

Authors and Affiliations

  1. Department of Neurological and Psychiatric Sciences, University of Florence, Viale Morgagni 85, I-50134, Florence, Italy

    S. Sorbi, B. Nacmias, M. Mortilla, S. Piacentini, G. Marcon, P. Piersanti, C. Ballerini, P. Forleo, S. Latorraca, G. Tesco & L. Amaducci

Authors
  1. S. Sorbi
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  2. B. Nacmias
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  3. M. Mortilla
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  4. S. Piacentini
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  5. G. Marcon
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  6. P. Piersanti
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  7. C. Ballerini
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  8. P. Forleo
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  9. S. Latorraca
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  10. G. Tesco
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  11. L. Amaducci
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Editor information

Editors and Affiliations

  1. Neurologische Universitätsklinik, Sigmund-Freud-Str. 25, W-5300, Bonn 1, Germany

    Alexander Hartmann

  2. Physiologisches Institut der Universität, Im Neuenheimer Feld 326, W-6900, Heidelberg, Germany

    Wolfgang Kuschinsky

  3. Abt. für Pathochemie und Allg. Neurochemie, Pathologisches Institut der Universität, Im Neuenheimer Feld 220-221, W-6900, Heidelberg, Germany

    Siegfried Hoyer

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© 1991 Springer-Verlag Berlin Heidelberg

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Cite this paper

Sorbi, S. et al. (1991). Linkage Analysis in Italian Pedigrees with Autosomal Dominant Familial Alzheimer’s Disease. In: Hartmann, A., Kuschinsky, W., Hoyer, S. (eds) Cerebral Ischemia and Dementia. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-76208-6_20

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  • DOI: https://doi.org/10.1007/978-3-642-76208-6_20

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-76210-9

  • Online ISBN: 978-3-642-76208-6

  • eBook Packages: Springer Book Archive

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