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Akutes fulminantes Leberversagen

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Therapie von Leber- und Gallekrankheiten

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Zusammenfassung

Das akute fulminante Leberversagen ist eine seltene Manifestation einer Leberkrankheit und stellt eine Notfallsituation dar. Das akute fulminante Leberversagen ist bedingt durch einen Verlust des Leberparenchyms aufgrund unterschiedlichster Ursachen. Trotz der Fortschritte des therapeutischen Managements und der Möglichkeit der Lebertransplantation ist die Mortalitätsrate weiterhin hoch. Dieses Kapitel befasst sich mit der Definition, den Ursachen, dem klinischen Bild, der Differentialdiagnose und dem Management des akuten fulminanten Leberversagens.

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Literatur

  • Böker K, Heringlake S (1999) Das akute Leberversagen. Klinikarzt 28:54–58

    Google Scholar 

  • Brunner G (1991) Diagnose und Therapie des fulminanten Leberversagens. Internist 32:256–261

    PubMed  CAS  Google Scholar 

  • Bundesärztekammer (2000) Richtlinien zur Organtransplantation gemäß §16 Transplantationsgesetz. Dtsch Ärztebl 97:352–367

    Google Scholar 

  • Caraceni P, Van Thiel DH (1995) Acute liver failure. Lancet 345:163–169

    Article  PubMed  CAS  Google Scholar 

  • Devlin J O’Grady J 1999 Indications for referral and assessment in adult liver transplantation a clinical guideline. Gut 45[Supp VI]; VI1–VI22

    Article  PubMed  Google Scholar 

  • Ellis AJ, Saleh M, Smith H, et al., (1995) Late-onset hepatic failure: clinical features, serology and outcome following transplantation. J Hepatol 23:363–372

    Article  PubMed  CAS  Google Scholar 

  • Emond JC, Aran PP, Whitington PF, et al., (1989) Liver transplantation in the management of fulminant hepatic failure. Gastroenterology 96:1583–1588

    PubMed  CAS  Google Scholar 

  • Hassanein TI, Wahlstrom HE, Zamora JU, Van Thiel DH (1997) Conventional care of fulminant hepatic failure: medical and surgical aspects. Ther Apher 1:33–37

    Article  PubMed  CAS  Google Scholar 

  • Hoofnagle JH, Carithers RL Jr, Shapiro C, Ascher N (1995) Fulminant hepatic failure: summary of a workshop. Hepatology 21:240–252

    PubMed  CAS  Google Scholar 

  • Jaeger A, Jehl F, Flesch F, et al., (1993) Kinetics of amatoxins in human poisoning: therapeutic implications. J Toxicol Clin Toxicol 31:63–80

    Article  PubMed  CAS  Google Scholar 

  • Knox TA, Olans LB (1996) Liver disease in pregnancy. N Engl J Med 335:569–576

    Article  PubMed  CAS  Google Scholar 

  • Kramer DJ, Aggarwal S, Martin M, et al., (1991) Management options in fulminant hepatic failure. Transplant Proc 23:1895–1898

    PubMed  CAS  Google Scholar 

  • Lake JR, Sussman NL (1995) Determining prognosis in patients with fulminant hepatic failure: when you absolutely, positively have to know the answer. Hepatology 21:879–882

    Article  PubMed  CAS  Google Scholar 

  • Lee WM (1993) Acute liver failure. N Engl J Med 329:1862–1871

    Article  PubMed  CAS  Google Scholar 

  • Lo SK, Wendon J, Mieli-Vergani,G, Williams R (1998). Halothane-induced acute liver failure: continuing occurrence and use of liver transplantation. Eur J Gastoenterol Hepatol 10:635–639

    CAS  Google Scholar 

  • Magann EF, Bass D, Chauhan SP, et al., (1994a) Antepartum corticosteroids: disease stabilization in patients with the syndrome of hemolysis, elevated liver enzymes, and low platelets (HELLP). Am J Obstet Gynecol 171:1148–1153

    PubMed  CAS  Google Scholar 

  • Magann EF, Perry KG Jr, Meydrech EF, et al., (1994b) Postpartum corticosteroids: accelerated recovery from the syndrome of hemolysis, elevated liver enzymes, and low platelets (HELLP). Am J Obstet Gynecol 171:1154–1158

    PubMed  CAS  Google Scholar 

  • O’Grady J, Alexander GJM, Hayallar KM, Williams R (1989) Early indicators of prognosis in fulminant hepatic failure. Gastroenterology 97:439–445

    PubMed  Google Scholar 

  • Plevris JN, Schina M, Hayes PC (1998) Review article: the management of acute liver failure. Aliment Pharmacol Ther 12:405–418

    Article  PubMed  CAS  Google Scholar 

  • Smilkstein MJ, Knapp GL, Kulig KW, Rumack BH (1988) Efficacy of oral N-acetylcysteine in the treatment of acetaminophen overdose. Analysis of the national multicenter study (1976 to 1985) 1557–1562

    Article  PubMed  CAS  Google Scholar 

  • Tibbs C, Williams R (1995) Viral causes and management of acute liver failure. J Hepatol 22[Suppl 1]: 68–73

    PubMed  CAS  Google Scholar 

  • Wiesner RH (1991) Acute fulminant hepatic failure. Transplant Proc 23:1892–1894

    PubMed  CAS  Google Scholar 

  • Williams R, Grimson AE (1991) Intensive liver care and management of acute liver failure. Dig Dis Sci 36:820–826

    Article  PubMed  CAS  Google Scholar 

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Authors
  1. B. H. Markus
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  2. C. Allers
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  3. W. F. Caspary
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Editor information

Editors and Affiliations

  1. Schwerpunkt Gastroenterologie, Direktor der Medizinischen Klinik II, Zentrum der Inneren Medizin, Universitätsklinikum Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt/Main, Germany

    W. F. Caspary

  2. Schwerpunkt Gastroenterologie, Medizinische Klinik II, Zentrum der Inneren Medizin, Universitätsklinikum Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt/Main, Germany

    U. Leuschner  & S. Zeuzem  & 

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© 2001 Springer-Verlag Berlin Heidelberg

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Markus, B.H., Allers, C., Caspary, W.F. (2001). Akutes fulminantes Leberversagen. In: Caspary, W.F., Leuschner, U., Zeuzem, S. (eds) Therapie von Leber- und Gallekrankheiten. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-56819-0_38

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  • DOI: https://doi.org/10.1007/978-3-642-56819-0_38

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-63151-1

  • Online ISBN: 978-3-642-56819-0

  • eBook Packages: Springer Book Archive

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