Skip to main content
SpringerLink
Log in

Nichtkleinzellige Lungenkarzinome

  • Chapter
Management des Lungenkarzinoms

Part of the book series: Onkologie ((ONKAKTUELL))

  • 109 Accesses

Zusammenfassung

Die Funktionsdiagnostik im Rahmen der Thoraxchirurgie dient der Festlegung der funktionellen Operabilität. Neben der Evaluierung kardialer Risiken kommt der Erfassung pulmonaler Funktionseinbußen besondere Bedeutung zu. Dies gründet in dem Faktum, dass Patienten, die wegen eines Lungenkarzinoms zur Operation anstehen, bedingt durch die inhalative Noxe „Zigarettenrauchen“, die für die Tumorentstehung verantwortlich ist, gleichzeitig in hoher Zahl (in 37–90 %) eine chronische obstruktive Bronchitis sowie ein fortgeschrittenes Lungenemphysem aufweisen — und zusätzlich durch Thorakotomie und Lungenresektion sich die pulmonale Funktion kurzzeitig, teilweise auch anhaltend verschlechtern kann.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 109.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 139.00
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Literatur

  • Abbot OA et al. (1950) Experiences with the surgical resection of the human carina, tracheal wall and contralateral bronchial wall in cases of the right total pneumonectomy. J Thorac Surg 19: 906

    Google Scholar 

  • ACC/AHA (1996) Guidelines for preoperative cardiovascular evaluation for noncardiac surgery. Circulation 93: 1278–1317

    Google Scholar 

  • Adkins PC (1983) Tumors of the chest wall. In: Shields TW (Hrsg) General thoracic surgery. Lea&Feabinger, Philadelphia

    Google Scholar 

  • Akeriey W, Herndon J, Turrisi A et al. (2000) Induction chemotherapy with paclitaxel (P) and carboplatin (C) followed by concurrent thoracic radiation and weekly PC for patients with unresectable stage III non-small-cell lung cancer (NSCLC): preliminary analysis of a phase II tial by the Cancer and Leukemia Group B. Proc Am Soc Clin Oncol 9: 1915a

    Google Scholar 

  • Akrawi W, Benumof JL (1997) A pathophysiological basis for informed preoperative smoking cessation counseling. J Cardiothorac Vasc Anesth 11: 629–640

    Article  PubMed  CAS  Google Scholar 

  • Albain K, Rush V, Crowley I, Griffin B, Beasley K, Liviingston R (1991) Concurrent cisplatin (DDP), VP-6, and chest irradiation (RT) followed by surgery for stages IIIa and IIIb nonsmall cell lung cancer (NSCLC): A Southwest Oncology Groups (SWOG) study (N° 8805). Proc Am Soc Clin Oncol 10 (244):A836

    Google Scholar 

  • American Cynamid Company (1989) Investigators Brochure Becker HD (1997) Photodynamische Therapie von Lungentumoren. Atemw Lungenkrh 23: 206–210

    Google Scholar 

  • American Society of Clinical Oncology (1997) Clinical practice guidelines for the treatment of unresectable non-small-cell lung cancer. J Clin Oncol 15: 2996–3018

    Google Scholar 

  • Antonadou D, Synodinou M, Boufi M et al. (2000) Amifostin reduces acute toxicity during radiochemotherapy in patients with localized advanced stage non-small-cell lung cancer. Proc Am Soc Clin Oncol 19: 501a

    Google Scholar 

  • Arcasoy SM, Jett JR (1997) Superior pulmonary sulcus tumors and Pancoast’s syndrome. N Engl J Med 1370: 337–343

    Google Scholar 

  • Ballantyne JC, Carr DB, deFerranti S, Suarez T, Lau J, Chalmers TC, Angelillo JF, Mosteller F (1998) The comparative effects of postoperative analgesic therapies on pulmonary outcome: cumulative meta-analyses of randomized, controlled trials. Anesth Analg 86: 598–612

    PubMed  CAS  Google Scholar 

  • Bechard D, Wetstein L (1987) Assessment of exercise oxygen consumption as preoperative criterion for lung resection. Ann Thorax Surg 44: 344–349

    Article  CAS  Google Scholar 

  • Becker HD (1994) Derzeitige Möglichkeiten und Grenzen der bronchoskopischen tracheobronchialen Schienung. Pneumologie 48: 182–190

    PubMed  CAS  Google Scholar 

  • Becker HD (1995a) Photodynamische Therapie. In: Huhn D, Herrmann R (Hrsg) Medikamentöse Therapie maligner Erkrankungen. Gustav Fischer, Stuttgart New York

    Google Scholar 

  • Becker HD (1995b) Treatment of postoperative bronchial fistulas by endoscopic fibrin application. In: Schlag G, Wolner E, Eckersberger F (eds) Fibrin sealing in surgical and nonsurgical fields. Cardiovascular Surgery — Thoracic Surgery 6. Springer, Berlin Heidelberg New York Tokyo, pp 186–193

    Chapter  Google Scholar 

  • Becker HD (2001) Photodynamische Therapie. In: Huhn D, Hermann R (Hrsg) Medikamentöse Therapie maligner Erkrankungen. Urban&Fischer, München Jena, pp 101–107

    Google Scholar 

  • Becker HD, Blersch E, Vogt-Moykopf I (1987) Urgent treatment of tracheal obstruction. In: Grillo H, Eschapasse H (eds) International trends in general thoracic surgery. Major Challenges. WB Saunders, Philadelphia London Toronto, 13–18

    Google Scholar 

  • Becker HD, Kayser K, Schulz V, Tuengerthal S, Vollhaber H-H (1991) Atlas of bronchoscopy. teechnique, diagnosis, differential diagnosis, therapy. B.C. Decker, Philadelphia Hamilton Becker

    Google Scholar 

  • Becker HD,Vogt-Moykopf I (1991) Möglichkeiten und Grenzen der endoskopischen Therapie beim Lungenkarzinom. In: Drings P, Vogt-Moykopf I (Hrsg) Thoraxtumoren, Springer, Berlin Heidelberg New York Tokyo, pp 187–198

    Google Scholar 

  • Becker HD, Wagner B, Lierman D, Urhoj S, Mechmann S (1995) Stenting of the central airways. In: Liermann D (ed) Stents. State of the art and future developments. Polyscience Publications, Morin Heights, Cnd, pp 249–255

    Google Scholar 

  • Becker HD, Waniek M, van Bodegom PC, Drings P (1993) Endoscopic laser therapy in the tracheobronchial system. Support Care Cancer 1: 47–51

    Article  PubMed  CAS  Google Scholar 

  • Beckett WS (1993) Epidemiology and etiology of lung cancer. In: Matthay RA (ed) Lung cancer. Clin Chest Med 14(1): 1–15

    Google Scholar 

  • Begg C, Cramer L, Hoskins W, Brennan M (1998) Impact of hospital volume on operative mortality for major cancer surgery. JAMA 280: 1747–1751

    Article  PubMed  CAS  Google Scholar 

  • Belani CP, Aisner J, Day R et al. (1997) Weekly paclitaxel and carboplatin with simultaneous thoracic radiotherapy (TRT) for locally advanced non-small-cell lung cancer (NSCLC): 3 year follow-up. Proc Am Soc Clin Oncol 16: 448a

    Google Scholar 

  • Betticher DC, Hasu Schmitz SF et al. (1999) Neoadjuvant chemotherapy with Docetaxel and Cisplatin in patients with non-small cell lung cancer stage IIIa, N2 is highly active with few toxicities. Proc ASCO 18: 473

    Google Scholar 

  • Billingham LJ, Cullen MH (2001) The benefits of chemotherapy in patient subgroups with unresectable non-small-cell lung cancer. Ann Oncol 12: 1671–1675

    Article  PubMed  CAS  Google Scholar 

  • Bloom ND (1995) Chestwall, pleura and sternum. In: Beattie EJ, Blom ND, Harvey JC (Hrsg) Thoracic surgical oncology. Churchill Livingstone, New York, pp 251–273

    Google Scholar 

  • Bolliger CT, Jordan P, Sober M et al. (1995) Exercise capacity as a predictor of postoperative complications in lung resection candidates. Am J Respir Crit Care Med 151: 1472–1480

    PubMed  CAS  Google Scholar 

  • Bolliger CT, Perruchoud AP (1998) Functional evaluation of the lung resection candidate. Eur Resp J 11: 198–212

    Article  CAS  Google Scholar 

  • Bolliger CT, Wyser C, Roser H, Soler M, Perruchoud AP (1995) Lung scanning and exercise testing for the prediction of postoperative performance in lung resection candidates at increased risk for complications. Chest 108: 341–348

    Article  PubMed  CAS  Google Scholar 

  • Bonnett R (1994) New photosensitisers for the photodynamic therapy of tumours. Proc Soc Photo-opt Instrum Eng 2078: 74–90

    CAS  Google Scholar 

  • Breathnach OS, Freidlin B, Conley B et al. (2001) Twenty-two years of phase III trials for patients with advanced non-small-cell lung cancer: sobering results. J Clin Oncol 19: 1734–1742

    PubMed  CAS  Google Scholar 

  • Brown SB, Vernon DI, Holryod JA, Marcus S, Trust R, Hawkins W, Shah A, Tonelli A (1992) Pharmakokinetics of Photofrin in Man. In: Spinelli P, Dal Fante M, Marchesini R (ed) Photodynamic therapy and biomedical lasers. Excerpta Medica, Amsterdam London New York Tokyo, pp 475–479

    Google Scholar 

  • Bryson GL, Laupacis A, Wells GA (1998) Does acute normovolemic hemodilution reduce perioperative allogeneic transfusion? A meta analysis. Anesth Analg 86: 9–15

    PubMed  CAS  Google Scholar 

  • Bülzebruck H, Bopp R, Drings P, Bauer E, Krysa S, Probst G, van Kaick G, Müller K-M, Vogt-Moykopf I (1992) New aspects in the staging of lung cancer. Cancer 70(5): 1102–1110

    Article  PubMed  Google Scholar 

  • Cartei G, Cartei F, Cantone A, Causarano D, Genco G, Tobaldin A, Interlandi G, Giraldi T (1993) Cisplatin-cyclophos-phamide-mitomycin combination chemotherapy with supportive care versus supportive care alone for treatment of metastatic non-small cell lung cancer. J Nat Cancer Inst 85: 794–800

    Article  PubMed  CAS  Google Scholar 

  • Cassina PC, Julke M, Weder W (1995) Thoracoscopic mediastinal lymph node dissection: an experimental study in pigs. Eur J Cardiothorac Surg 9: 544–547

    Article  PubMed  CAS  Google Scholar 

  • Cavaliere S, Foccoli P, Toninelli C, Feijo S (1994) Nd:YAG laser therapy in lung cancer: an 11-year experience with 2,253 applications in 1,585 patients. J Bronchol 1: 105–111

    Article  Google Scholar 

  • Cellerino R, Tummarello D, Guido F, Isidori P, Raspugli M, Biscottini B (1991) A randomized trial of alterning chemotherapy versus best supportive care in advanced non-small cell lung cancer. J Clin Oncol 9: 1454–1461

    Google Scholar 

  • Chapelier A, Fadel E, Macchiarini P et al. (2001) Factors affecting long-term results after en-bloc resection of lung cancer invading the chest wall. Eur J Card-Thorac Surg 18: 513–518

    Article  Google Scholar 

  • Choy H, Akerley W, Safran H et al. (1998) Multi-institutional phase II trial of paclitaxel, carboplatin. and concurrent radiation therapy for locally advanced non-small-cell lung cancer. J Clin Oncol 16: 3316–3322

    PubMed  CAS  Google Scholar 

  • Choy H, DeVore RD, Akerley W et al. (2000) Sequential phase II studies of paclitaxel ± carboplatin and radiation therapy (± hyperfractionation HFXRT) for locally advanced non-small-cell lung cancer (NSCLC): multi-institutional trials. Proc Am Soc Clin Oncol 19: 499a

    Google Scholar 

  • Cigolari S, Curcio C, Massimo M, Sessa R, Palmieri EA, Vasta M, Maiorino A (1998) Vinorelbine (VNR)-cisplatin (c) combination neoadjuvant chemotherapy in stage IIIb non-small cell lung cancer (NSCLC): results after 2 years. Lung Cancer 21(Suppl 1): S53

    Article  Google Scholar 

  • Cormier YD, Bergeron J, la Forge, Lavandrier M, Foernier M, Chenard J, Desmeules M (1982) Benefits of polychemotherapy in advanced non small cell bronchogenic carcinoma. Cancer 50: 845

    Article  PubMed  CAS  Google Scholar 

  • Cotes JE, Chinn DJ, Quanjer PH, Roca J, Yernault JC (1993) Standardization of the measurement of transfer-factor (diffusing capacity). Europ Resp J 6(Suppl 16): 43

    Google Scholar 

  • Cullen MH, Billingham LJ, Woodroffe CM et al. (1999) Mitomycin, ifosfamide and cisplatin in unresectable non-small cell lung cancer: effects on survival and quality of life. J Clin Oncol 17: 3188–3194

    PubMed  CAS  Google Scholar 

  • Curran WJ, Scott C, Langer C et al. (2000) Phase III comparison of sequential vs concurrent chemoradiation for PTS with unresected stage III nonsmall cell lung cancer (NSCLC): initial report of Radiation Therapy Oncology Group (RTOG) 9410. Proc Am Soc Clin Oncol 19: 1891a

    Google Scholar 

  • Dartevelle PG, Chapelier AR, Macchiarini P et al. (1993) Anterior transcervical-thoracic approach for radical resection of lung tumors invading the thoracic inlet. J Thorac Cardiovasc Surg 105(6): 1025–1034

    PubMed  CAS  Google Scholar 

  • Dartevelle P, Macchiarini P (1996) Carinal resection for bronchogenic carcinoma. Sem Thorac Cardiovasc Surg 8: 414

    CAS  Google Scholar 

  • Depierre A, Milleron B, Moro-Sibilot D et al. (2002) Preoperative chemotherapy followed by surgery compared with primary surgery in resectable stage I (except T1 No), II, and IIIa non-small-cell lung cancer. J Clin Oncol 20: 247–253

    Article  PubMed  Google Scholar 

  • Desai SJ, Mehta AC, Van der Brug-Medendorp S, Gollish JA, Ahmad M (1988) Survival experience following Nd:YAG laser photoresection for primary bronchogenic carcinoma. Chest 94: 939–944

    Article  PubMed  CAS  Google Scholar 

  • Deslauriers J, Beaulieu M, McClish A (1989) Tracheal-sleeve pneumonectomy. In: Shields TW (ed) General Thoracic Surgery, 3rd ed. Philadelphia: Lea&Febinger: p 382

    Google Scholar 

  • Deutsche Gesellschaft für Pneumologie (1994) Empfehlungen zur präoperativen Lungenfunktionsdiagnostik. Pneumologie 48: 296–299

    Google Scholar 

  • Deutsche Gesellschaft für Pneumologie (2000) Empfehlungen zur Diagnostik des Lungenkarzinoms. Pneumologie 54: 361–371

    Article  Google Scholar 

  • Dienemann H (1996) Lungen-und Lungensystem. In: Reichart B, Denecke H, Muhr G (Hrsg) Spezielle Chirurgische Therapie. Huber, Bern, pp 222–295

    Google Scholar 

  • Dienemann H (1998) Operationen an Brustwand und Thorax. Zentralbl Chir 128: 1204–1215

    Google Scholar 

  • Dienemann H (2001) Principles of surgical treatment in localized non-small cell lung cancer. Lung Cancer 33(Suppl): S3–S8

    Article  PubMed  Google Scholar 

  • Dienemann H, Link B, Muley T, Hoffmann H (2002) Morbidität und Letalität bronchoplastischer und angioplastischer Operationen bei NSCLC. Chir Praxis, im Druck

    Google Scholar 

  • Digl W (2000) Welchen Stellwert hat die neoadjuvante Therapie in der Behandlung beim Lungenkarzinom? Zentralbl Chir 125: 315–318

    Google Scholar 

  • Donat SM, Levy DA (1998) Bleomycin-associated pulmonary toxicity: is perioperative oxygen restriction necessary? J Urol 160: 1347–1352

    Article  PubMed  CAS  Google Scholar 

  • Dougerty TJ (1989) Photodynamic therapy — new approaches. Sem Surg Oncol 5: 6–16

    Article  Google Scholar 

  • Downey RJ, Martini N, Rusch VW, Bains MS, Korst RJ, Ginsberg RJ (1999) Extent of chest wall invasion and survival in patients with lung cancer. Ann Thorac Surg 68(1): 188–193

    Article  PubMed  CAS  Google Scholar 

  • Drings P, Manegold C (1995) Multidisciplinary approach in treatment of lung cancer. In: Carpagnano F, De Lena M (eds) Recent advances in lung cancer. Masson, Milano

    Google Scholar 

  • Dumon JF (1990) A dedicated tracheobronchial stent. Chest 97: 328–332

    Article  PubMed  CAS  Google Scholar 

  • Dumon JF, Shapshay S, Bourceraou J, Cavaliere S, Meric B, Garbi N, Beamis J (1984) Principles for safety in application of Neodymium-YAG laser in bronchology. Chest 86: 163–168

    Article  PubMed  CAS  Google Scholar 

  • Durrant KR, Berry RJ, Ellis F, Ridehalgh FR, Black JM, Hamilton WS (1971) Comparison of treatment policies in inoperable bronchial carcinoma. Lancet 1: 715–719

    Article  PubMed  CAS  Google Scholar 

  • Eagan RT, Ruud C, Lee R, Pairolero PC, Gail MA for the Lung Cancer Study Group (1987) A pilot study of induction therapy with cyclophosphamide, doxorubicin, cis-platinum (CAP) and chest irradiation prior to thoracotomy in initially inoperable stage II MO non-small cell lung cancer. Cancer Treat Rep 71: 895–900

    PubMed  CAS  Google Scholar 

  • Eberhardt W, Wilke H, Stamatis G et al. (1998) Preoperative chemotherapy followed by concurrent chemoradiation therapy based on hyperfractionated accelerated radiotherapy and definitive surgery in locally advanced non-small-cell lung cancer: Mature Results of a phase II trial, J Clin Oncol 16: 622–634

    PubMed  CAS  Google Scholar 

  • Edell ES, Cortese DA (1987) Bronchoscopic phototherapy for malignancies of the tracheobronchial tree. Laser Med Surg 3: 137–141

    Google Scholar 

  • Elias AD, Herdon J, Kumar P, Shugarbaker D, Green MR for the Cancer and Leukemia Group B (1997) A phase III comparison of „best local-regional therapy“ with or without chemotherapy for stage IIIA T2-3 N2 non-small cell lung cancer: Preliminary results. Proc Amer Soc Clin Oncol 16: 448

    Google Scholar 

  • Elias AD, Skarin AT, Leong T, Sugarbaker DJ (1996) Neoadjuvant therapy for surgically staged IIIA N2 non-small cell lung cancer. Lung Cancer 17: 149–161

    Google Scholar 

  • Elias AD, Skarin A, Socinski MA, Kalish L, Frei III E (1989) Neoadjuvant therapy for stage IIIa non-small cell lung cancer (NSCLC). Proc Am Soc Clin Oncol 8(241): A941

    Google Scholar 

  • Emanuel EJ, Emanuel LL (1994) The economics of dying — the illusions of cost savings at the end of life. N Engl J Med 330: 540–544

    Article  PubMed  CAS  Google Scholar 

  • Faber LP, Jensik RJ, Kittle CF (1995) Results of sleeve lobectomy for bronchogenic carcinoma in 101 patients. Ann Thorac Surg 37: 279

    Article  Google Scholar 

  • Facciolo F, Cardillo G, Lopergolo M et al. (2001) Chest wall invasion in non-small cell lung carcinoma: a rationale for en bloc resection. J Thorac Cardiovasc Surg 121: 649–656

    Article  PubMed  CAS  Google Scholar 

  • Farin G, Grund KE (1994) Technology of argon plasma coagulation with particular regard to endoscopic applications. End Surg 2: 71–77

    CAS  Google Scholar 

  • Ferguson MK, Little L, Rizzo L, Popovich KJ, Clonek GF, Ley A, Manjoney D, Little AG (1988) Diffusion capacity predicts morbidity and mortality after pulmonary resection. J Thorax Cardiovasc Surg 96: 894–900

    CAS  Google Scholar 

  • Freitag L, Tekolf E, Linz B, Greschuchna D (1993) A new dynamic airway stent. Chest 104(2): 44

    Google Scholar 

  • Fritz P, Schraube P, Becker HD, Wannenmacher M, Pastyr O (1991) A new applicator positionable to the center of the tracheobronchial lumen for HDR — IR — 192 — Afterloading of tracheobronchial tumors. Int J Rad Oncology Biol Phys 20: 1061–1066

    Article  CAS  Google Scholar 

  • Furukawa K, Yamamoto H, Crean DH, Kato H, Mang TS (1996) Localization and treatment of transformed tissues using the photodynamic sensitizer 2-(1-hexyloxaethyl)-2-devnyl pyropheophorbide-a. Lasers Surg Med 18: 157–166

    Article  PubMed  CAS  Google Scholar 

  • Furuse K, Fukuoka M, Kato H (1993) A prospective phase II study on photodynamic therapy with photofrin II for centrallly located early-stage lung cancer. J Clin Oncol 11: 1852–1857

    PubMed  CAS  Google Scholar 

  • Furuse K, Fukuoka M, Kawahara M et al. (1999) Phase III study of concurrent versus sequential thoracic radiotherapy in combination with mitomycin, vindesine, and cisplatin in unresectable stage III non-small-cell lung cancer. J Clin Oncol 17: 2692–2699

    PubMed  CAS  Google Scholar 

  • Furuse K, Hosoe S, Masuda N et al. (2000) Impact of tumor control on survival in unresectable stage III non-small-cell lung cancer (NSCLQ treated with concurrent thoracic radiotherapy (TRT) and chemotherapy (CT). J Clin Oncol 19: 1893

    Google Scholar 

  • Gandara DR, Lovato LC, Albain KS et al. (2000) Prolonged survival in pathologic stage IIIB non-small-cell lung cancer (NSCLC) with concurrent chemoradiotherapy followed byconsolidation docetaxel: a phase II study (S9504) of the Southwest Oncology Group (SWOG). Proc Am Soc Clin Oncol 19: 1916

    Google Scholar 

  • Ganz PA, Figlin RA, Hasekell CM, la Soto N, Siau J (1989) Supportive care versus supportive care and combination chemotherapy in metastatic non-small cell lung cancer. Cancer 63: 1271–1278

    Article  PubMed  CAS  Google Scholar 

  • Ginsberg RJ, Rubinstein LV (1995) Randomized trial of lobectomy versus limited resection for T1N0 non-small cell lung cancer. Lung Cancer Study Group. Ann Thorac Surg 60: 615–622

    Article  PubMed  CAS  Google Scholar 

  • Goodnough LT, Brecher ME, Kanter MH, AuBouchon JP (1999a) Transfusion medicine. First of two parts. Blood transfusion. N Engl J Med 340: 438–447

    Article  PubMed  CAS  Google Scholar 

  • Goodnough LT, Brecher ME, Kanter MH, AuBouchon JP (1999b) Transfusion medicine. Second of two parts. Blood conservation. N Engl J Med 340: 525–533

    Article  PubMed  CAS  Google Scholar 

  • Gridelli C for the Elderly Lung Cancer Vinorelbine Italian Study Group (1999) Effect of vinorelbine on quality of life and survival in elderly patients with advanced non-small cell lung cancer. J Nat Canc Inst 91: 66–72

    Article  Google Scholar 

  • Grillo HC (1982) Carinal reconstruction. Ann Thorac Surg 34:356

    Article  PubMed  CAS  Google Scholar 

  • Grillo H (1987) Urgent treatment of tracheal obstruction. Discussion. In: Grillo H, Eschapasse H (eds) International trends in general thoracic surgery. Major challenges. WB Saunders, Philadelphia London Toronto, pp 19–20

    Google Scholar 

  • Grund KE, Storek D, Farin G (1994) Endoscopic Argon Plasma Coagulation (APC). First clinical experiences in flexible endoscopy. End Surg 2: 42–46

    CAS  Google Scholar 

  • Hager ED (1989) Photo dynamische Therapie — lichtaktivierte Moleküle in der Krebsdiagnostik und Krebstherapie. Dtsch Z Onkol 12: 34–41

    Google Scholar 

  • Hall EJ (1994) Radiobiology for the radiologist. JB Lippincott, Philadelphia

    Google Scholar 

  • Hansen E, Knuechel R, Altmeppen J, Taeger K (1999) Blood irradiation for intraoperative autotransfusion in cancer surgery: demonstration of efficient elimination of contaminating tumor cells. Transfusion 39: 608–615

    Article  PubMed  CAS  Google Scholar 

  • Harms W, Becker HD, Krempien R, Wannenmacher M (2001) Contemporary role of modern brachytherapy techniques in the management of malignant thoracic tumors. Sem Surg Oncol 20: 57–65

    Article  CAS  Google Scholar 

  • Harms W, Schraube P, Becker HD, Latz D, Herth F, Fritz P, Wannenmacher M (2000) Effect and toxicity of endoluinal high dose rate (HDR) brachytherapy in centrally located tumors of the upper respiratory tract. Strahlenther Onkol 176: 60–66

    Article  PubMed  CAS  Google Scholar 

  • Hata E, Hayakawa K, Miyamoto H, Hayashida R (1990) Rationale for extended lymphadenectomy in lung cancer. Theor Surg 5: 19–25

    Google Scholar 

  • Hazelrigg SR, Landreneau RJ, Boley TM et al. (1991) The effect of muscle-sparing versus standard posterolateral thoracotomy on pulmonary function, muscle strength, and postoperative pain. J Thorac Cardiovasc Surg 101(3): 394–400; discussion 400-401

    PubMed  CAS  Google Scholar 

  • Heitmann C, Pelzer M, Menke H, Germann G (2000) The free musculocutaneous tensor fascia lata flap as a backup procedure in tumor surgery. Ann Plast Surg 45: 399–404

    Article  PubMed  CAS  Google Scholar 

  • Hermanek P (1995) Diagnostische Standards Lungen-, Magen-, Pankreas-und kolorektales Karzinom. W. Zuckschwerdt, München

    Google Scholar 

  • Hermanek P, Hutter RV, Sobin LH, Wittekind C (1999) International Union Against Cancer. Classification of isolated tumor cells and micrometastasis. Cancer 86: 2668–2673

    Article  PubMed  CAS  Google Scholar 

  • Homasson JP, Renault P, Angebault M,Bonniot JP, Bell NJ (1986) Bronchoscopic cryotherapy for airway strictures caused by tumors. Chest 90: 159–164

    Article  PubMed  CAS  Google Scholar 

  • Hooper RG, Jackson FN (1985) Endobronchial electro cautery. Chest 87: 712–714

    Article  PubMed  CAS  Google Scholar 

  • Hu JS, Lui PW, Wang H, Chan KH, Luk HN, Tsou MY, Lee TY (2000) Thoracic epidural analgesia with morphine does not prevent postthoracotomy pain syndrome: a survey of 159 patients. Acta Anaesthesiol Sin 38(4): 195–200

    PubMed  CAS  Google Scholar 

  • Hua Z, Gibson SL, Foster TH, Hilf R (1995) Effectiveness of delta-aminolevulinic acid-inducedprotoporphyrin as a photosensitizer for photodynamic therapy in vivo. Cancer Res 55: 1723–1731

    PubMed  CAS  Google Scholar 

  • Huber RM, Fischer R, Hautmann H, Pollinger B, Haussinger K, Wendt T (1997) Does additional brachytherapy improve the effect of external irradiatiion? Aprospective, randomized study in central lung tumors. Int J Radiat Oncol Biol Phys 37: 533–540

    Article  Google Scholar 

  • Hurford WE, Kolker AC, Strauss HW (1987) The use of ventilation/perfusion lung scans to predict oxygenation during one-lung-anesthesia. Anesthesiology 67: 841–844

    Article  PubMed  CAS  Google Scholar 

  • Izbicki JR, Passlick B, Karg O, Bloechle C, Knoefel WT, Thetter O (1995) Impact of radical systematic lymphadenectomy on tumor staging in lung cancer. Ann Thorac Surg 59: 209–14

    Article  PubMed  CAS  Google Scholar 

  • Izbicki JR, Passlick B, Pantel K, Pichlmeier U, Hosch SB, Karg O, Thetter O (1998) Effectiveness of radical systematic mediastinal lymphadenectomy in patients with resectable non-small cell lung cancer — Results of a prospective randomized study. Ann Surg 227: 138–144

    Article  PubMed  CAS  Google Scholar 

  • Jensik RJ et al. (1982) Survival in patients undergoing tracheal sleeve pneumonectomy for bronchogenic carcinoma. J Thorac Cardiovasc Surg 84: 489

    PubMed  CAS  Google Scholar 

  • Jones NL, Campbell EJM (1982) Clinical Exercise Testing, 2nd ed. Saunders, Philadelphia

    Google Scholar 

  • Jordan S, Mitchell JA, Quinlan GJ, Goldstraw P, Ewans TW (2000) The pathogenesis of lung injury following pulmonary resection. Eur Respir J15: 790–799

    Article  Google Scholar 

  • Junker K, Bonorden S, Becker HD, Müller K-M (1993) Morphologische Befunde nach endobronchialer photodynamischer Therapie. Verh Dtsch Ges Path 77: 367

    Google Scholar 

  • Kaseda S, Hangai N, Yamamoto S, Kitano M (1997) Lobectomy with extended lymph node dissection by video-assisted thoracic surgery for lung cancer. Surg Endosc 11: 703–706

    Article  PubMed  CAS  Google Scholar 

  • Kashtan H, Haddad R, Yossipov Y, Bar-On S (1996) Photodynamic therapy of colorectal cancer using a new light source: from in vitro studies to a patient treatment. Dis Colon Rectum 39: 379–383

    Article  PubMed  CAS  Google Scholar 

  • Kato H, Sakai H, Konaka C, Okunaka T, Furukawa K, Aizawa K, Saito Y, Hayata Y (1992) Fluorescence photodiagnosis of early stage lung cancer. In: Spinelli P, Dal Fante M, Marchesini R (ed) Photodynamic therapy and biomedical lasers. Excerpta Medica, Amsterdam London New York Tokyo, pp 876–882

    Google Scholar 

  • Kato D, Suzuki H (1989) Selective destruction of cancer cell membranes by the Argon-Laser Photochemotherapy (PTC) with hematoporphyrin and its application to a clinical gastric cancer. Laser Med Surg 5: 202–209

    Google Scholar 

  • Kayser K, Anyanwu E, Vogt-Moykopf I (1993) Tumor presence at resection boundaries and lymph node metastasis in bronchial carcinoma patients. Thorac Cardiovasc Surgeon 41: 308–311

    Article  CAS  Google Scholar 

  • Keller SM, Adak S, Wagner H, Johnson DH (2000) Mediastinal lymph node dissection improves survival in patients with stages II and IIIa non-small cell lung cancer. Ann Thorac Surg 70: 358–365

    Article  PubMed  CAS  Google Scholar 

  • Kelly JF, Delclos ME, Morice RC et al. (2000) High dose rate endobronchial brachytherapy effectively palliates symptoms due to air way tumors: the 10 year M. D. Anderson Cancer Center experience. Int J Radiat Oncol Biol Phys 48: 697–702

    Article  PubMed  CAS  Google Scholar 

  • Kessel D (1998) PDT: Expanding the database. An update on new drugs and mechanisms of phototoxcity. Photodynamics 1: 2–4

    Google Scholar 

  • Kiyono K, Sone S, Sakai F, Imai Y, Watanabe T, Izuno I, Oguchi M, Kawai T, Shigematsu H, Watanabe M (1988) The number and size of normal mediastinal lymph nodes: a post mortem study. Am J Roentgenol 150: 771–776

    CAS  Google Scholar 

  • Komaki R, Seriferheld W, Curran W et al. (2000) Sequential vs concurrent chemotherapy and radiation therapy for inoperable nonsmall cell lung cancer (NSCLC): analysis of failures in a phase III study (RTOG 9410). Int J Radial Oncol Biol Phys 48: 5

    Article  Google Scholar 

  • Kongshaug M, Cheng LS, Moan J, Morgan AR (1995) Binding of etiopurpurin and tin-coordinated etiopurpurin to human plasma proteins. Delivery in cremophore EL and dimethyl sulfoxide. Int J Biochem Cell Biol 27: 71–87

    Article  PubMed  CAS  Google Scholar 

  • Korst RJ, Ginsberg RJ (2001) Appropriate surgical treatment of resectable non-small-cell lung cancer. World J Surg 25: 184–188

    Article  PubMed  CAS  Google Scholar 

  • Kostenich G, Orenstein A, Rotman L, Malik Z, Ehrenberg B (1997) In vivo photodynamic therapy with the new near-IR absorbing water soluble photosensitizer lutetium texaphyrin and a high intensity pulsed light delivery system. J Photochem Photobiol 39: 36–42

    Article  CAS  Google Scholar 

  • Laing AH, Berry RJ, Newman CR, Peto J (1975) Treatment of inoperable carcinoma of the bronchus. Lancet 2: 1161–1164

    Article  PubMed  CAS  Google Scholar 

  • Lam S, Kennedy T, Unger M et al. (1998) Localization of bronchial intraepithelial neoplastic lesions by fluorescence bronchoscopy. Chest 113: 696–702

    Article  PubMed  CAS  Google Scholar 

  • Landreneau RJ, Sugarbaker DJ, Mack MJ et al. (1997) Wedge resection versus lobectomy for stage I (T1N0M0) non-small-cell lung cancer. J Thorac Cardiovasc Surg 113: 691–700

    Article  PubMed  CAS  Google Scholar 

  • Levy JG (1994) Photosensitizers in photodynamic therapy. Semin Oncol 21(Suppl 15): 4–10

    PubMed  CAS  Google Scholar 

  • Lewis RJ (1993) The role of video-assisted thoracic surgery for carcinoma of the lung: wedge resection to lobectomy by simultaneous individual stapling. Ann Thorac Surg 56: 762–768

    Article  PubMed  CAS  Google Scholar 

  • Lewis RJ, Caccavale RJ (1998) Video-assisted thoracic surgical non-rib spreading simultaneously stapled lobectomy (VATS (n)SSL). Semin Thorac Cardiovasc Surg 10: 332–339

    PubMed  CAS  Google Scholar 

  • Lewis RJ, Caccavale RJ, Sisler GE (1991) Special report: video-endoscopic thoracic surgery. N Eng J Med 88: 473–475

    CAS  Google Scholar 

  • Liewald F, Hatz R, Dienemann H, Sunder-Plassmann L (1992) Importance of microscopic residual disease at the bronchial margin after resection for non-small cell carcinoma of the lung. J Thorac Cardiovasc Surg 104: 408–412

    PubMed  CAS  Google Scholar 

  • Loh CS, MacRobert AJ, Bedwell J, Regula J, Krasner N, Bown SG (1993) Oral versus intravenous administration of 5-aminole-vulinic acid for photodynamic therapy. Br J Cancer 68: 41–51

    Article  PubMed  CAS  Google Scholar 

  • Macchiarini P, Dartevelle P (1998) Extended resections for lung cancer. In: Roth JA, Hong WK, Cox JD (eds) Lung Cancer, 2nd ed. Cambridge, MA, Blackwell Scientific Publications: pp 135–162

    Google Scholar 

  • Macha HN, Koch K, Stadler M, Schumacher W, Krumhaar D (1987) New technique for treating occlusive and stenosing tumours of the trachea and main bronchi: endobronchial irradiation by high dose iridium-192 combined with laser canalisation. Thorax 42: 511–515

    Article  PubMed  CAS  Google Scholar 

  • Magdeleinat P, Alifano M, Benbrehem C et al. (2001) Surgical treatment of lung cancer invading chest wall: results and prognostic factors. Ann Thorac Surg 71: 1094–1099

    Article  PubMed  CAS  Google Scholar 

  • Manegold C (2001) Chemotherapy in stage I/II NSCLC and projects of the EORTC — lung cancer group for early stage lung cancer. Lung Cancer 34: 53–58

    Article  Google Scholar 

  • Manegold C (2002) Die medikamentöse Therapie des nicht-kleinzelligen Lungenkarzinoms. In: Manegold C (Htsg) Therapieoptionen beim nicht-kleinzelligen Lungenkarzinom. Uni-med-Verlag, Bremen, pp 102–116

    Google Scholar 

  • Manegold C, Bergman B, Chemaissani A et al. (1997) Single agent gemcitabine versus cisplatin-etoposide: Early results of a randomised phase II study in locally advanced or metastatic non-small cell lung cancer. Ann Onol 8: 525–529

    Article  CAS  Google Scholar 

  • Markos J, Mullan BP, Hillmann DR, Musk AW, Antico VF, Lovegrave FT, Carter MJ, Finucane KE (1989) Preoperative assessment as a predictor of mortality and morbidity after lung resection. Am Rev Respir Dis 139: 902–910

    PubMed  CAS  Google Scholar 

  • Markus SL (1996) 5-Aminolevulinic Acid. International Photo-dynamics 1: 2–4

    Google Scholar 

  • Marsiglia H, Baldeyrou P, Lartigau E et al. (2000) High-dose-rate brachytherapy as a sole modality for early-stage endobronchial carcinoma. Int J Radiat Oncol Biol Phys 47: 665–672

    Article  PubMed  CAS  Google Scholar 

  • Martini N, Flehinger BJ, Zaman MB, Beattie EJ (1983) Results of resection of non-oat cell carcinoma of the lung with mediastinal lymph node metastases. Ann Surg 198: 386–397

    Article  PubMed  CAS  Google Scholar 

  • Martini N, Rusch VW, Bains MS (1999) Factors influencing ten-year-survival in resected stages I-IIIA non-small cell lung cancer. J Thorac Cardiovasc Surg 117: 32–38

    Article  PubMed  CAS  Google Scholar 

  • Massard G, Doddoli C, Gasser B, Ducrocq X, Kessler R, Schumacher C, Jung GM, Wihlm JM (2000) Prognostic implications of a positive bronchial resection margin. Eur J Cardiothorac Surg 17: 557–565

    Article  PubMed  CAS  Google Scholar 

  • Mathes DD (1995) Bleomycin and hyperoxia exposure in the operating room. Anesth Analg 81: 624–629

    PubMed  CAS  Google Scholar 

  • Mathisen DJ, Grillo HC (1989) Endoscopic relief of malignant airway obstruction. Ann Thorac Surg 48: 469–475

    Article  PubMed  CAS  Google Scholar 

  • Mathisen DJ, Grillo HC (1991) Carinal resection for bronchogenic carcinoma. J Cardivasc Surg 102: 16

    CAS  Google Scholar 

  • McKenna RJ Jr, Wolf RK, Brenner M, Fischel RJ, Wurnig P (1998) Is lobectomy by video-assisted thoracic surgery an adequate cancer operation? Ann Thorac Surg 66: 1903–1908

    Article  PubMed  Google Scholar 

  • Møller AM, Villebro N, Pedersen T, Tonnesen H (2002) Effect of preoperative smoking intervention on postoperative complications: a randomised clinical study. Lancet 359: 114–117

    Article  PubMed  Google Scholar 

  • Moores LK (2000) Smoking and postoperative pulmonary complications. An evidence-based review of the recent literature. Clin Chest Medicine 21(1): 139–146

    Article  CAS  Google Scholar 

  • Mountain CF (1997) Revisions in the international system for staging lung cancer. Chest 111: 1710–1717

    Article  PubMed  CAS  Google Scholar 

  • Müller K-M, Becker HD, Junker K (1992) Histomorphologische Veränderungen an der Lungenwand nach Einwirkung des Nd-YAG-Lasers und nach photo dynamischer Lasertherapie. Lasermedizin 8: 120–121

    Google Scholar 

  • Naruke T (2000) Mediastinal Lymph Node Dissektion. In: Shields TW, LoCicero J, Ponn RB (Hrsg) General Thoracic Surgery. Lippincott, Philadelphia, pp 1343–1356

    Google Scholar 

  • Non-Small Cell Lung Cancer Collaborative Group (1995) Chemotherapy in non-small cell lung cancer: A meta-analysis using updated data on individual patients from 52 randomised clinical trials. BMJ 331: 899–909

    Article  Google Scholar 

  • O’Brien M, Smith IE, Postmus PE et al. for the EORTC-LCCG (1999) Taxol and Carboplatin induction chemotherapy in stage IIIa non-small cell lung cancer: An EORTC 08958 phase II trial. Proc ASCO 18: 942

    Google Scholar 

  • Ohta Y, Oda M, Wu J, Tsunezuka Y, Hiroshi M, Nonomura A, Watanabe G (2001) Can tumor size be a guide for limited surgical intervention in patients with peripheral non-small cell lung cancer? Assessment from the point of view of nodal micrometastasis. J Thorac Cardiovasc Surg 122: 900–906

    Article  PubMed  CAS  Google Scholar 

  • Oosterhuis JA, Theunissen PH, Bollen EM (2001) Improved pre-operative mediastinal staging in non-small-cell lung cancer by serial sectioning and immunohistochemical staining of lymph-node biopsies. Eur J Cardio Thorac Surg 20: 335–338

    Article  CAS  Google Scholar 

  • Orenstein A, Kostench G, Roitman L, Shechtman Y, Kopolovic Y, Ehrenberg B, Malik Z (1996) A comparative study of tissue distribution and photodynamic therapy selectivity of chlorin e6, Photofrin and ALA-induced protoporphyrin X in a colon carcinoma model. Br J Cancer 73: 937–944

    Article  PubMed  CAS  Google Scholar 

  • Pairolero PC (1999) Extended resections for lung cancer. How far is too far ? Eur J Cardiothorac Surg 16(1) 48–50

    Article  Google Scholar 

  • Pancoast HK (1924) Importance of careful roentgen-ray investigations of apical chest tumors. JAMA 83: 1407–1411

    Article  Google Scholar 

  • Paulson DL, Shaw NN (1955) Bronchoplastic procedures for bronchogenic carcinoma. J Thorac Cardiovasc Surg 59: 38–48

    Google Scholar 

  • Pass HI (1993) Photodynamic therapy in oncology: mechanisms and clinical use. J Nat Cancer Inst 85(6): 443–456

    Article  PubMed  CAS  Google Scholar 

  • Pass HI, Pogrebniak HW, Steinberg SM, Mulshine J, Minna JD (1992) Randomized trial of neoadjuvant therapy for lung cancer: interim analysis. Ann Thorac Surg 53: 992–998

    Article  PubMed  CAS  Google Scholar 

  • Passlick B, Izbicki JR, Kubuschok B, Thetter O, Pantel K (1996) Detection of disseminated lung cancer cells in lymph nodes: Impact on staging and prognosis. Ann Thorac Surg 61: 177–183

    Article  PubMed  CAS  Google Scholar 

  • Passlick B, Kubuschok B, Izbicki JR, Thetter O, Pantel K (1999) Isolated tumor cells in bone marrow predict reduced survival in node-negative non-small cell lung cancer. Ann Thorac Surg 68: 2053–2058

    Article  PubMed  CAS  Google Scholar 

  • Passlick B, Sitar I, Sienel W, Thetter O, Morresi HA (2001) Significance of lymphangiosis carcinomatosa at the bronchial resection margin in patients with non-small cell lung cancer. Ann Thorac Surg 72: 1160–1164

    Article  PubMed  CAS  Google Scholar 

  • Peng Q, Warloe T, Berg k, Kongshaug M, Giercksky KE, Nesland JM (1997) 5-Aminolevulinic acid-based photodynamic therapy. Clinical research and future challenges. Cancer 79: 2282–2308

    Article  PubMed  CAS  Google Scholar 

  • Pincus M, Reddy S, Lee MS, Bonomi P, Taylor S, Rowland K, Faber LP, Warren W, Kittle CF, Hendricksen FR (1989) Preoperative combined modality therapy for stage III MO non-small cell lung carcinoma. Int J Radiat Oncol Bio Phys 15: 189–195

    Article  Google Scholar 

  • Port Meta-analysis Trialists Group (1998) Postoperative radiotherapy in non-small-cell lung cancer: systematic review and meta-analysis of individual patient data from nine randomised controlled trials. Lancet 352: 257–263

    Article  Google Scholar 

  • Potter V, Woll PJ (2001) Chemotherapy in non small cell lung cancer. In: Spiro SG (ed) Lung Cancer. European Respiratory Monograph 6: Monograph 17. European Respiratory Society Journals, Sheffield, UK, pp 218–233

    Google Scholar 

  • Prakash UBS, Freitag L (1994) Hemoptysis and bronchoscopy-induced hemorrhage. In: Prakash UBS (ed) Bronchoscopy. Raven Press, New York, pp 227–251

    Google Scholar 

  • Quanjer PH, Tammeling GJ, Cotes JE, Pedersen OF, Peslin R, Yernault JC (1993) Lung volumes and forced ventilatory flows. Europ Resp J 6(Suppl 16): 5

    Google Scholar 

  • Rapp E, Pater JL, Willan A et al. (1988) Chemotherapy can prolong survival in patients with advanced non-small cell lung cancer — report of a Canadian multicenter randomized trial. J Clin Oncol 6: 633–641

    PubMed  CAS  Google Scholar 

  • Rodgers A, Walker N, Schug S (2000) Reduction of postoperative mortality and morbidity with epidural or spinal anaesthesia: results from overview of randomised trials. Br Med J 321: 1–12

    Article  Google Scholar 

  • Rosell R, Gomez-Godina J, Camps C et al. (1994) A randomized trial comparing preoperative chemotherapy plus surgery with surgery alone in patients with non-small cell lung cancer. N Engl J Med 330: 153–158

    Article  PubMed  CAS  Google Scholar 

  • Rosell R, Gómez-Codina J, Camps C et al. (1999) Preresectional chemotherapy in stage IIIA non-small-cell lung cancer: a 7-year assessment of a randomized controlled trial. Lung Cancer 26: 7–14

    Article  PubMed  CAS  Google Scholar 

  • Roth JA, Atkinson EN, Fossella F et al. (1998) Long-term followup of patients enrolled in a randomized trial comparing perioperative chemotherapy and surgery with surgery alone in resectable stage IIIA non-small-cell lung cancer. Lung Cancer 21: 1–6

    Article  PubMed  CAS  Google Scholar 

  • Roth JA, Fosella F, Ritsuko R et al. (1994) A randomized trial comparing perioperative chemotherapy and surgery with surgery alone in resectable non-small cell lung cancer. Natl Cancer Inst 86: 673–680

    Article  CAS  Google Scholar 

  • Roviaro G, Rebuffat C, Varoli F, Vergani C, Mariani C, Maciocco M (1992) Videoendoscopic pulmonary lobectomy for cancer. Surg Laparosc Endosc 2: 244–247

    PubMed  CAS  Google Scholar 

  • Roviaro G, Varoli F, Vergani C, Maciocco M (1998) Video-assisted thoracoscopic surgery (VATS) major pulmonary resections: the Italian experience. Semin Thorac Cardiovasc Surg 10: 313–320

    PubMed  CAS  Google Scholar 

  • Rusch VW et al. (2001) Induction chemoradiation and surgical resection for non-smal cell lung carcinomas of the superior sulcus: Initial results of Southwest Oncology Group Trial 9416 (Intergroup Trial 0160). J Thorac Cardiovasc Surg 121(3): 472–483

    Article  PubMed  CAS  Google Scholar 

  • Saito M, Yokoyama A, Kurita Y, Uematsu T, Tsukada H, Yamanoi T (2000) Treatment of roentgnographically occult endobronchial carcinoma with external beam radiotherapy and intralumenal low dose rate brachytherapy: second part. Int J Radiat Oncol Biol Phys 47: 673–80

    Article  PubMed  CAS  Google Scholar 

  • Schiller JH, Harrington D, Belani CP, Langer C, Sandier A, Krook J, Zhu J, Johnson DH (2002) Comparison of four chemotherapy regimens for advanced non small cell lung cancer. N Engl J Med 346: 92–98

    Article  PubMed  CAS  Google Scholar 

  • Schinkel C, Dienemann H, Reinmiedl J, Hoffmann H, Muller C, Schildberg FW (1999) Verteilungsmuster und Befall regionarer Lymphknoten bei nicht-kleinzelligem Lungencarcinom. Chirurg 70: 179–183

    Article  PubMed  CAS  Google Scholar 

  • Schraube P, Fritz P, Becker HD, Wannenmacher M (1993) Ergebnisse der endoluminalen High-dose-rate-Bestrahlung von zentralen nichtkleinzelligen Lungenkarzinomen. Strahlenherapie und Onkologie 4: 228–234

    Google Scholar 

  • Schumaker RD, Choy H, Akerley W et al. (2000) Tumor volume decrease is a predictor of survival following combined modality therapy for stage III non-small-cell lung cancer: retrospective analysis of multi-institutional trial. Am Soc Clin Oncol 19: 1977

    Google Scholar 

  • Shaw RR, Paulson DL, Kee JLJ (1961) Treatment of the superior sulcus tumor by irradiation followed by resection. Ann Surg 154: 29–36

    Article  PubMed  CAS  Google Scholar 

  • Shea JM, Allen RP, Tharratt RS, Chan AL. Siefkin AD (1993) Survival of patients undergoing Nd:YAG laser therapy compared with Nd:YAG laser therapy and brachytherapy for malignant airway disease. Chest 103: 1028–1031

    Article  PubMed  CAS  Google Scholar 

  • Shepherd FA, Carney DN (2000) Treatment of NSCLC: chemotherapy. In: Hansen HH (ed) Lung Cancer IASLC. Martin Dunitz, London

    Google Scholar 

  • Siewert JR, Vogelsang HE (2001) Prinzipien der Chirurgie maligner Tumoren. In: Siewert JR, Harder F, Rothmund M (Hrsg) Praxis der Viszeralchirurgie. Springer, Berlin Heidelberg New York Tokyo, S 187–196

    Google Scholar 

  • Smith TP, Kinasewitz GT, Tucker WY, Spikers WP, George RB (1984) Exercise capacity as a predictor of postthoracotomy morbidity. Am Rev Respir Dis 129: 730

    PubMed  CAS  Google Scholar 

  • Snijder RJ, Brutel de la Rivière A, Elbers HJ, van den Bosch JM (1998) Survival in resected stage I lung cancer with residual disease at the bronchial resection margin. Ann Thorac Surg 65: 212–216

    Article  PubMed  CAS  Google Scholar 

  • Socinski MA, Halle J, Schell MJ et al. (2000) Induction (1) and concurrent (C) carboplatin/paclitaxel (C/P) with dose-escalated thoracic conformai radiotherapy (TCRT) in stage IIIA/B non-small-cell lung cancer (NSCLC): a phase I/II trial. Am Soc Clin Oncol 19: 1940

    Google Scholar 

  • Solaini L, Prusciano F, Bagioni P, Di Francesco F, Basilio Poddie D (2001) Video-assisted thoracic surgery major pulmonary resections. Present experience. Eur J Cardiothorac Surg 20: 437–442

    Article  PubMed  CAS  Google Scholar 

  • Souquet PJ, Chauvin F, Boissel JP et al. (1993) Polychemotherapy in advanced non small cell lung cancer: A metanalysis. Lancet 342: 19–21

    Article  PubMed  CAS  Google Scholar 

  • Stutschke M, Eberhardt C: Prophylactic cranial irradiation in locally advanced non-small-cell lung cancer after multimodality treatment: long term follow-up and investigations of late neuropsychologic effects. J Clin Oncol 1999 Sep, 17(9): 2700–2709

    Google Scholar 

  • Stewart IA, Pignon JP for Non-small Cell Cancer Cooperative Group (1995) Chemotherapy in non-small cell lung cancer: a meta-analysis using updated data on individual patients from 52 randomised clinical trials. Brit Med J 311: 899–909

    Article  Google Scholar 

  • Strauss GM, Langer MP, Elias AD, Skarin AT, Sugarbaker DI (1992) Multimodality treatment of stage III. A non-small cell lung carcinoma: A critical review of literature and strategies for further research. J Clin Oncol 10: 829–838

    PubMed  CAS  Google Scholar 

  • Sugi K, Kaneda Y, Esato K (2000) Video-assisted thoracoscopic lobectomy achieves a satisfactory long-term prognosis in patients with clinical stage IA lung cancer. World J Surg 24: 27–30

    Article  PubMed  CAS  Google Scholar 

  • Sutedja G, Postmus PE (1994) Bronchoscopic treatment of lung tumors. Lung Cancer 11: 1–17

    Article  PubMed  CAS  Google Scholar 

  • Tedder M et al. (1992) Current morbidity, mortality, and survival after bronchoplastic procedures for malignancy. Ann Thorac Surg 54: 387–391

    Article  PubMed  CAS  Google Scholar 

  • Thomas M, Rübe C, Semik M et al. (1999) Impact of preoperative bimodality induction including twice-daily radiation on tumor regression and survival in stage III non-small cell lung cancer. J Clin Oncol 17: 1185–1193

    PubMed  CAS  Google Scholar 

  • Tobias JW (1932) Sindrome apico-costo-vertebral-doloroso por tumor apexiano: su valor diagnostico en el cancer primitivo del pulmon. Rev Med Lat Am 19: 1552–1556

    Google Scholar 

  • Tonnesen H, Rosenberg J, Nielsen HJ, Rasmussen V, Hauge C, Pedersen IK, Kehlet H (1999) Effect of preoperative abstinence on poor postoperative outcome in alcohol misusers: randomised controlled trial. Br Med J 318: 1311–1316

    Article  CAS  Google Scholar 

  • Trédaniel J, Hennequin C, Zalcam G et al. (1994) Prolonged survival after high-dose-rate endobronchial irradiation for malignant airway obstruction. Chest 105: 767–772

    Article  PubMed  Google Scholar 

  • Trybulla M, Taylor SG, Bonomi P (1985) Preoperative simultaneous cisplatin/5-fluorouracil and radiotherapy in clinical stage III, non-small cell bronchogenic carcinoma. Proc Am Soc Clin Oncol 4(182): A710

    Google Scholar 

  • Tsuchiya R (1998) Bronchoplastic bronchovascular techniques. In: Pearson (ed) Thoracic Surgery

    Google Scholar 

  • Tsuchiya R et al. (1990) Resection of tracheal carina for lung cancer. J Thorac Cardiovasc Surg 99: 779

    PubMed  CAS  Google Scholar 

  • Unsöld E, Baumgartner R, Jocham D, Stepp H (1987) Application of photosensitizers in diagnosis and therapy. Laser Med Surg 3: 210–214

    Google Scholar 

  • Vamvakia EC (1996) Transfusion-associated cancer recurrence and postoperative infection: meta-analysis of randomized controlled clinical trials. Transfusion 32: 175–186

    Article  Google Scholar 

  • van Zandwijk N, Smit EF, Kramer GWP et al. (2000) Gemcitabine and Cisplatin as inducition regimen for patients with biopsy-proven stage IIIa N2 non-small cell lung cancer: a phase II study of the European Organization for Research and Treatment of Cancer. Lung Cancer Cooperative Group (EORTC 08955). J Clin Oncol 18: 2658–2664

    PubMed  Google Scholar 

  • Vogt-Moykopf I, Fritz TH, Meyer G (1986) Bronchoplastic and angioplastic operation in bronchial carcinoma: Long term results of a retrospective analysis from 1973 to 1983. In Surg 71: 211

    CAS  Google Scholar 

  • Walker WS (1998) Video-assisted thoracic surgery (VATS) lobectomy: the Edinburgh experience. Semin Thorac Cardiovasc Surg 10: 291–299

    PubMed  CAS  Google Scholar 

  • Walker WS, Craig SR (1996) Video-assisted thoracoscopic pulmonary surgery — current status and potential evolution. Eur 1 Cardiothorac Surg 10: 161–167

    Article  CAS  Google Scholar 

  • Walsh DA, Maiwand MO, Nath AR, Lockwood P, Lloyd MH, Saab M (1990) Bronchoscopic cryotherapy for advanced bronchial carcinoma. Thorax 45: 509–513

    Article  PubMed  CAS  Google Scholar 

  • Walsh GL, Moore RC, Putnam JB (1994) Resection of lung cancer is justified in high-risk patients selected by exercise oxygen consumption. Ann Thorac Surg 58: 704–710

    Article  PubMed  CAS  Google Scholar 

  • Watanabe Y (2000) Tracheal sleeve pneumonectomy. In: Shields TW, LoCicero J, Ponn RB (eds) General Thoracic Surgery. Philadelphia: Lippicott, Williams&Wilkins: pp 423–432

    Google Scholar 

  • Warren WH, Faber LP (1994) Segmentectomy versus lobectomy in patients with stage I pulmonary carcinoma. Five-year survival and patterns of intrathoracic recurrence. J Thorac Cardiovasc Surg 107: 1087–1094

    PubMed  CAS  Google Scholar 

  • Weber A, Stammberger U, Inci I, Schmid RA, Dutly A, Weder W (2001) Thoracoscopic lobectomy for benign disease. A single centre study on 64 cases. Eur J Cardiothorac Surg 20: 443–448

    Article  PubMed  CAS  Google Scholar 

  • Weisel R et al. (1979) Sleeve lobectomy for carcinoma of the lung. J Thorac Cardiovasc Surg 78: 839–849

    PubMed  CAS  Google Scholar 

  • Weisman JM (2001) Combined use of exercise testing, lung function tests and radionuclide imagines to select lung cancer patients for surgical resections. 97th International conference ATS, San Francisco, 18-23.05.2001, A72, p 185

    Google Scholar 

  • Wilson BC (1998) Light sources for photodynamic therapy. Photodynamics 1: 6–8

    Google Scholar 

  • Woods RL, Williams CJ, Levi J, Page J, Bell D, Byrne M, Kerestes ZL (1990) A randomized trial of cisplatin and vindesine versus supportive care only in advanced non-small cell lung cancer. Br J Cancer 61: 608–611

    Article  PubMed  CAS  Google Scholar 

  • Yamamoto N, Fukuoka M, Negoro S et al. (2000) A phase II study of induction chemotherapy (M CT) with C PT-11 and cisplatin followed by thoracic radiation (TRT) combined with weekly CPT-11 in patients with unresectable stage III non-small-cell lung cancer (NSCLC). Proc Am Soc Clin Oncol 19: 1953a

    Google Scholar 

  • Yim A, Landreneau RJ, Izzat MB, Fung ALK, Wan S (1998) Is video-assisted thoracoscopic lobectomy a unified approach? Ann Thorac Surg 66: 1155–1158

    Article  PubMed  CAS  Google Scholar 

Download references

Authors
  1. V. Schulz
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Abteilung Innere Medizin — Onkologie, Thoraxklinik-Heidelberg gGmbH Akademisches Lehrkrankenhaus der Universität Heidelberg, Amalienstraße 5, 69126, Heidelberg, Germany

    P. Drings

  2. Chirurgische Abteilung, Thoraxklinik-Heidelberg gGmbH Akademisches Lehrkrankenhaus der Universität Heidelberg, Amalienstraße 5, 69126, Heidelberg, Germany

    H. Dienemann

  3. Abteilung Klinische Radiologie (Schwerpunkt Strahlentherapie) und Poliklinik, Radiologische Klinik der Ruprecht-Karls-Universität Heidelberg, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany

    M. Wannenmacher

Rights and permissions

Reprints and permissions

Copyright information

© 2003 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Schulz, V. (2003). Nichtkleinzellige Lungenkarzinome. In: Drings, P., Dienemann, H., Wannenmacher, M. (eds) Management des Lungenkarzinoms. Onkologie Aktuell . Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-55602-9_13

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-55602-9_13

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-62774-3

  • Online ISBN: 978-3-642-55602-9

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation