Abstract
The compression or severance of an axon results in important ultrastructural changes at the regenerating segment. While in a normal myelinated axon only less than 1% of the volume is occupied by axially oriented material composed of neuro-tubules and neurofilaments (de Robertis and Franohi, 1953; Thornburg and de Robertis, 1956) after sectioning the proximal stump becomes loaded with mitochondria, neurotubules and numerous clear and dense core (i.e. granulated) vesicles (for lit. see Lubinska, 1964; Pellegrino de Iraldi and de Robertis, 1968).
This wok has been supported by grants from the Consejo Nacional de Investigaciones, Cientificas y Técnicas, Argentina and U. S. Air Force (AF-AFOSR 67-0963 A).
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de Iraldi, A.P., de Robertis, E. (1970). Studies on the Origin of the Granulated and Nongranulated Vesicles. In: Schümann, HJ., Kroneberg, G. (eds) New Aspects of Storage and Release Mechanisms of Catecholamines. Bayer Symposium, vol 2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-49747-6_3
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