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Definition, Classification, and Clinical Presentation of Chronic Radiation Syndrome (CRS) Associated with Total Exposure to External Radiation

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Chronic Radiation Syndrome

Abstract

The development of nuclear industry and wide application of radioactive isotopes and ionizing radiation (IR) in the industry, medicine, science, and other fields of man’s activity considerably increased the number of people affected by long-term radiation exposure. The operation of nuclear enterprises was performed without proper protection of the personnel. As a result, already in the early 1950s physicians noted the development of a specific clinical syndrome associated with long-term exposure to IR in doses exceeding the threshold for the appearance of tissue reactions. Follow-up of these exposed persons demonstrated that they develop a number of consecutive system changes that gradually form the chronic radiation syndrome (CRS). Russian scientists (Guskova et al. 1954; Kurshakov 1956; Glazunov et al. 1959; Baysogolov 1961; Kireyev 1962, etc.) showed that changes in hematopoietic and nervous systems dominate in clinical CRS picture. The chapter also presents the classification of the chronic radiation syndrome.

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Authors and Affiliations

  1. Clinical Department, Urals Research Centre for Radiation Medicine, Chelyabinsk, Russia

    Alexander V. Akleyev MD, PhD

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  1. Alexander V. Akleyev MD, PhD
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Akleyev, A.V. (2014). Definition, Classification, and Clinical Presentation of Chronic Radiation Syndrome (CRS) Associated with Total Exposure to External Radiation. In: Chronic Radiation Syndrome. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-45117-1_1

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  • DOI: https://doi.org/10.1007/978-3-642-45117-1_1

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-45116-4

  • Online ISBN: 978-3-642-45117-1

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