Limit Values and Guideline Values in Regulatory Toxicology

Abstract

Depending on the matrix (e.g., water, air) and the classification of a substance (e.g., contaminant), a multitude of limits and guidelines has been defined. The motivation for defining such a limit or guideline can be different. The most important reason is to protect the population from adverse health effects such as acute chronic toxicity or cancer. Another reason could be the protection of ecosystems which could be more vulnerable than humans. Moreover, aesthetic considerations, like the taste and/or odor of drinking water, can result in limitations of chemicals. In the following chapter, definitions of and examples for limits in water, air, or occupational environments are given. These lists are by no means exhaustible.