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Elektrolyt- und Säure-Basen-Haushalt

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NeuroIntensiv

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Zusammenfassung

Das Gesamtkörpernatrium eines 70 kg schweren Menschen liegt bei 4200 mmol. Davon befi nden sich 40 % im Knochen, 10 % intra- und transzellulär und 50 % im Extrazellularraum. Die intrazelluläre Natriumkonzentration wird mit 5−20 mmol/l je nach Gewebe und Nachweismethode angegeben. Die Natriumkonzentration im Extrazellularraum liegt bei rund 145 mmol/l und wird durch osmotische Mechanismen relativ eng konstant gehalten. Natrium ist als wichtigstes Kation im extrazellulären Raum zusammen mit den Anionen Chlorid (105 mmol/l) und Bicarbonat (26 mmol/l) für die Osmolarität verantwortlich. Der Konzentrationsgradient zwischen intra- und extrazellulärem Natrium wird durch das Natrium-Kalium-ATPase-Enzymsystem als biochemisches Korrelat des transmembranen Transports aufrechterhalten [7].

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Authors and Affiliations

  1. Abteilung Anästhesiologie, Kreisklinik Ebersberg, Pfarrer-Guggetzer-Str. 3, 85560, Ebersberg

    Dr. N. Forster

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Editors and Affiliations

  1. Neurologische Klinik, Friedrich-Alexander-Universität Erlangen-Nürnberg, Schwabachanlage 6, 91054, Erlangen

    Stefan Schwab

  2. Benediktuskrankenhaus, Neurologische Klinik und Geriatrie Johannes Wesling Klinikum Minden, Hans-Nolte-Str. 1, 32429, Minden

    Peter Schellinger

  3. Klinik für Anästhesiologie, Klinikum der Johannes Gutenberg-Universität Mainz, Langenbeckstr. 1, 55131, Mainz

    Christian Werner

  4. Neurochirurgische Klinik, Ruprecht-Karls-Universität Heidelberg, Im Neuenheimer Feld 400, 69120, Heidelberg

    Andreas Unterberg  & Werner Hacke  & 

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Forster, N. (2012). Elektrolyt- und Säure-Basen-Haushalt. In: Schwab, S., Schellinger, P., Werner, C., Unterberg, A., Hacke, W. (eds) NeuroIntensiv. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-16911-3_12

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  • DOI: https://doi.org/10.1007/978-3-642-16911-3_12

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-16910-6

  • Online ISBN: 978-3-642-16911-3

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