Summary
In this paper we propose a new procedure for peak detection in mass-spectrometry data using sparse deconvolution. We apply the procedure for estimation of the ion charges for isotopic patterns of overlapping peaks. The evaluation is performed on the thymosin β4 16-38 fragment measurements. Moreover, a comparison with the Mexican hat based algorithm of peak picking is provided.
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Bredies, K., Alexandrov, T., Decker, J., Lorenz, D.A., Thiele, H. (2010). Sparse Deconvolution for Peak Picking and Ion Charge Estimation in Mass Spectrometry. In: Fitt, A., Norbury, J., Ockendon, H., Wilson, E. (eds) Progress in Industrial Mathematics at ECMI 2008. Mathematics in Industry(), vol 15. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-12110-4_43
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DOI: https://doi.org/10.1007/978-3-642-12110-4_43
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