Skip to main content
SpringerLink
Log in

Aufarbeitung und Beurteilung von Biopsien, Operationspräparaten und axillären Lymphknoten

  • Chapter
  • First Online:
Book cover Pathologie

Part of the book series: Pathologie ((PATHOL))

  • 5746 Accesses

Zusammenfassung

Das wichtige Kapitel behandelt die für die adäquate Diagnostik in der Pathologie notwendige technische Bearbeitung der Stanzbiopsie, des Exzidats, der Segmentektomie oder des Mastektomiepräparats. Besonders wird auf die standardmäßige Behandlung des therapeutischen Exzidats eingegangen.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 299.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Literatur

  1. Bässler R (1997) Axillares Dissektionspräparat. In: Remmele W (ed) Pathologie. Springer, Berlin Heidelberg New York, p 355

    Google Scholar 

  2. Bässler R, Schnurch HG (1994) Standards of pathohistologic processing of breast cancer. A contribution to quality assurance in pathology and patient care. Gynäkologe 27:23–36

    PubMed  Google Scholar 

  3. Bijker N, Meijnen P, Peterse JL et al (2006) Breast-conserving treatment with or without radiotherapy in ductal carcinoma-in-situ: ten-year results of European Organisation for Research and Treatment of Cancer randomized phase III trial 10853 – a study by the EORTC Breast Cancer Cooperative Group and EORTC Radiotherapy Group. J Clin Oncol 24:3381–3387

    Article  PubMed  Google Scholar 

  4. Bleiweiss IJ, Nagi CS, Jaffer S (2006) Axillary sentinel lymph nodes can be falsely positive due to iatrogenic displacement and transport of benign epithelial cells in patients with breast carcinoma. J Clin Oncol 24:2013–2018

    Article  PubMed  Google Scholar 

  5. Bollmann R (1990) Localization of radiologically detected, non-palpable breast changes. Pathologe 11:195

    PubMed  CAS  Google Scholar 

  6. Carter BA, Jensen RA, Simpson JF, Page DL (2000) Benign transport of breast epithelium into axillary lymph nodes after biopsy. Am J Clin Pathol 113:259–265

    Article  PubMed  CAS  Google Scholar 

  7. Chan JK, Frizzera G, Fletcher CD, Rosai J (1992) Primary vascular tumors of lymph nodes other than Kaposi's sarcoma. Analysis of 39 cases and delineation of two new entities. Am J Surg Pathol 16:335–350

    Article  PubMed  CAS  Google Scholar 

  8. Chan JK, Warnke RA, Dorfman R (1991) Vascular transformation of sinuses in lymph nodes. A study of its morphological spectrum and distinction from Kaposi's sarcoma. Am J Surg Pathol 15:732–743

    Article  PubMed  CAS  Google Scholar 

  9. Clarke M, Collins R, Darby S et al (2005) Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trials. Lancet 366:2087–2106

    PubMed  CAS  Google Scholar 

  10. Creager AJ, Geisinger KR, Shiver SA et al (2002) Intraoperative evaluation of sentinel lymph nodes for metastatic breast carcinoma by imprint cytology. Mod Pathol 15:1140–1147

    Article  PubMed  Google Scholar 

  11. Cserni G, Bianchi S, Boecker W, Decker T, Lacerda M, Rank F, Wells CA (2005) Improving the reproducibility of diagnosing micrometastases and isolated tumor cells. Cancer 103:358–367

    Article  PubMed  Google Scholar 

  12. Decker T et al (2006) Pathologic diagnosis in minimal invasive biopsy. In: Böcker W (ed) Preneoplasia of the breast. A new conceptual approach to proliferative breast disease. Saunders Elsevier, München, pp 81–106

    Google Scholar 

  13. Decker T et al (2006) Pathologic diagnosis in surgical specimens. In: Böcker W (ed) Preneoplasia of the breast. A new conceptual approach to proliferative breast disease. Saunders Elsevier, München, pp 107–128

    Google Scholar 

  14. Diaz NM, Vrcel V, Centeno BA, Muro-Cacho C (2005) Modes of benign mechanical transport of breast epithelial cells to axillary lymph nodes. Adv Anat Pathol 12:7–9

    Article  PubMed  Google Scholar 

  15. Dillon MF, Hill AD, Quinn CM, McDermott EW, O'Higgins N (2006) A pathologic assessment of adequate margin status in breast-conserving therapy. Ann Surg Oncol 13:333–339

    Article  PubMed  Google Scholar 

  16. Emdin SO, Granstrand B, Ringberg A et al (2006) SweDCIS: Radiotherapy after sector resection for ductal carcinoma in situ of the breast. Results of a randomised trial in a population offered mammography screening. Acta Oncol 45:536–543

    Article  PubMed  Google Scholar 

  17. Faverly DR, Burgers L, Bult P, Holland R (1994) Three dimensional imaging of mammary ductal carcinoma in situ: clinical implications. Semin Diagn Pathol 11:193–198

    PubMed  CAS  Google Scholar 

  18. Fisher B, Dignam J, Wolmark N et al (1998) Lumpectomy and radiation therapy for the treatment of intraductal breast cancer: findings from National Surgical Adjuvant Breast and Bowel Project B-17. J Clin Oncol 16:441–452

    PubMed  CAS  Google Scholar 

  19. Fisher CJ, Hill S, Millis RR (1994) Benign lymph node inclusions mimicking metastatic carcinoma. J Clin Pathol 47:245–247

    Article  PubMed  CAS  Google Scholar 

  20. Giuliano AE, Chung AP (2010) Long-term follow-up confirms the oncologic safety of sentinel node biopsy without axillary dissection in node-negative breast cancer patients. Ann Surg 251:601–603

    Article  PubMed  Google Scholar 

  21. Giuliano AE, Han SH (2011) Local and regional control in breast cancer: role of sentinel node biopsy. Adv Surg 45:101–116

    Article  PubMed  Google Scholar 

  22. Giuliano AE, Hunt KK, Ballman KV et al (2011) Axillary dissection vs no axillary dissection in women with invasive breast cancer and sentinel node metastasis: a randomized clinical trial. JAMA 305:569–575

    Article  PubMed  CAS  Google Scholar 

  23. Hermanek P, Hutter RV, Sobin LH, Wittekind C (1999) International Union Against Cancer. Classification of isolated tumor cells and micrometastasis. Cancer 86:2668–2673

    Article  PubMed  CAS  Google Scholar 

  24. Hetelekidis S, Schnitt SJ, Silver B et al (2000) The significance of extracapsular extension of axillary lymph node metastases in early-stage breast cancer. Int J Radiat Oncol Biol Phys 46:31–34

    Article  PubMed  CAS  Google Scholar 

  25. Hoda SA, Resetkova E, Yusuf Y, Cahan A, Rosen PP (2002) Megakaryocytes mimicking metastatic breast carcinoma. Arch Pathol Lab Med 126:618–620

    PubMed  Google Scholar 

  26. Holland R, Veling SH, Mravunac M, Hendriks JH (1985) Histologic multifocality of Tis, T1-2 breast carcinomas. Implications for clinical trials of breast-conserving surgery. Cancer 56:979–990

    Article  PubMed  CAS  Google Scholar 

  27. Julien JP, Bijker N, Fentiman IS et al (2000) Radiotherapy in breast-conserving treatment for ductal carcinoma in situ: first results of the EORTC randomised phase III trial 10853. Lancet 355:528–533 (EORTC Breast Cancer Cooperative Group and EORTC Radiotherapy Group)

    Article  PubMed  CAS  Google Scholar 

  28. Junkermann H, Anton HW, Krapfl E, Harcos A, von Fournier D (1993) Clarification of breast lesions using core-cut, drill and fine needle biopsy. Radiologe 33:267–270

    PubMed  CAS  Google Scholar 

  29. Kuhn T (2011) Sentinel lymph node biopsy in early breast cancer. Breast Care (Basel) 6:185–191

    Article  Google Scholar 

  30. Layfield LJ, Mooney E (2000) Heterotopic epithelium in an intramammary lymph node. Breast J 6:63–67

    Article  PubMed  Google Scholar 

  31. Linden MD, Zarbo RJ (2001) Cytokeratin immunostaining patterns of benign, reactive lymph nodes: applications for the evaluation of sentinel lymph node specimen. Appl Immunohistochem Mol Morphol 9:297–301

    Article  PubMed  CAS  Google Scholar 

  32. Mabry H, Giuliano AE (2007) Sentinel node mapping for breast cancer: progress to date and prospects for the future. Surg Oncol Clin N Am 16:55–70

    Article  PubMed  Google Scholar 

  33. Moore KH, Thaler HT, Tan LK, Borgen PI, Cody 3rd HS (2004) Immunohistochemically detected tumor cells in the sentinel lymph nodes of patients with breast carcinoma: biologic metastasis or procedural artifact. Cancer 100:929–934

    Article  PubMed  Google Scholar 

  34. Perry N, Broeders M, de Wolf C, Törnberg S, Holland R, von Karsa L (eds) (2006) European guidelines for quality assurance in breast cancer screening and diagnosis. Office for Official Publications of the European Communities, Luxembourg

    Google Scholar 

  35. Ridolfi RL, Rosen PP, Thaler H (1977) Nevus cell aggregates associated with lymph nodes: estimated frequency and clinical significance. Cancer 39:164–171

    Article  PubMed  CAS  Google Scholar 

  36. Roberts CA, Beitsch PD, Litz CE et al (2003) Interpretive disparity among pathologists in breast sentinel lymph node evaluation. Am J Surg 186:324–329

    Article  PubMed  Google Scholar 

  37. Schwartz GF, Giuliano AE, Veronesi U (2002) Proceedings of the consensus conference on the role of sentinel lymph node biopsy in carcinoma of the breast April 19 to 22, 2001, Philadelphia, Pennsylvania. Hum Pathol 33:579–589

    Article  PubMed  Google Scholar 

  38. Schwartz GF, Giuliano AE, Veronesi U (2002) Proceedings of the consensus conference on the role of sentinel lymph node biopsy in carcinoma of the breast, April 19-22, 2001, Philadelphia, Pennsylvania. Cancer 94:2542–2551

    Article  PubMed  Google Scholar 

  39. Silverstein MJ (1997) Predicting residual disease and local recurrence in patients with ductal carcinoma in situ. J Natl Cancer Inst 89:1330–1331

    Article  PubMed  CAS  Google Scholar 

  40. TNM (2010) Klassifikation maligner Tumoren. Wiley-VCH, Weinheim

    Google Scholar 

  41. Truong LD, Cartwright Jr J, Goodman MD, Woznicki D (1988) Silicone lymphadenopathy associated with augmentation mammaplasty. Morphologic features of nine cases. Am J Surg Pathol 12:484–491

    Article  PubMed  CAS  Google Scholar 

  42. Turner DR, Millis RR (1980) Breast tissue inclusions in axillary lymph nodes. Histopathology 4:631–636

    Article  PubMed  CAS  Google Scholar 

  43. Turner RR, Weaver DL, Cserni G et al (2008) Nodal stage classification for breast carcinoma: improving interobserver reproducibility through standardized histologic criteria and image-based training. J Clin Oncol 26:258–263

    Article  PubMed  Google Scholar 

  44. van Diest PJ, Beekman WH, Hage JJ (1998) Pathology of silicone leakage from breast implants. J Clin Pathol 51:493–497

    Article  PubMed  Google Scholar 

  45. Weaver DL (2011) Handling and evaluation of sentinel lymph nodes. In: O'Malley FP, Pinder SE, Mulligan AM (eds) Breast pathology. Churchill Livingstone, Elsevier, Philadelphia, pp 287–294

    Chapter  Google Scholar 

  46. Wong JS, Kaelin CM, Troyan SL et al (2006) Prospective study of wide excision alone for ductal carcinoma in situ of the breast. J Clin Oncol 24:1031–1036

    Article  PubMed  Google Scholar 

Download references

Author information

Author notes

  1. Werner Böcker Prof. em. Dr. med.

    Present address: Referenz- und Konsultationszentrum für Gynäko- und Mammapathologie, Fangdieckstr. 75a, 22547, Hamburg, Deutschland

Authors and Affiliations

  1. Gerhard Domagk Institut für Pathologie der Universität Münster, Münster, Deutschland

    Werner Böcker Prof. em. Dr. med.

Authors
  1. Werner Böcker Prof. em. Dr. med.
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Werner Böcker Prof. em. Dr. med. .

Editor information

Editors and Affiliations

  1. Institut für Pathologie, Konsultationszentrum für Pankreas- und, TU München, Ismaninger Str. 22, München, 81675, Germany

    Günter Klöppel

  2. Inst. Pathologie, Medizinische Hochschule Hannover (MHH), Carl-Neuberg-Str. 1, Hannover, 30623, Germany

    Hans Kreipe

  3. Kliniken der Landeshauptstadt, Institut für Pathologie, Ludwig-Erhard-Straße 100, Wiesbaden, 65199, Germany

    Wolfgang Remmele

  4. Charite - Universitätsmedizin Berlin, Campus Charité Mitte, Institut für Pathologie, Charitéplatz 1, Berlin, 10117, Berlin, Germany

    Manfred Dietel

Rights and permissions

Reprints and permissions

Copyright information

© 2013 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Böcker, W. (2013). Aufarbeitung und Beurteilung von Biopsien, Operationspräparaten und axillären Lymphknoten. In: Klöppel, G., Kreipe, H., Remmele, W., Dietel, M. (eds) Pathologie. Pathologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-04564-6_15

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-04564-6_15

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-04563-9

  • Online ISBN: 978-3-642-04564-6

  • eBook Packages: Medicine (German Language)

Publish with us

Policies and ethics

Search

Navigation