Abstract
Though cancer is a rare event during pregnancy, of those which are recorded, cervical cancer is one of the commonest encountered. As the age group who embark on starting a family correlates with a higher incidence of cervical cancer, the coincidental finding of this association is understandable. This contrasts with endometrial cancer—a disease primarily developing after the menopause, when of course, pregnancy is not feasible. Therefore, in pregnancy-related cancers, these two form either end of the spectrum of diseases. As with all such situations, care is complicated because of the desire (or not) to continue with a pregnancy and the endeavour to balance the probabilities of achieving a live baby without compromising the mother’s survival prospects.
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References
Ayhan A, Gunalp S, Karaer C, Gokoz A, Oz U (1999) Endometrial adenocarcinoma in pregnancy. Gynecol Oncol 75(2): 298–299
Bandyopadhyay S, Chatterjee R(2006) HPV viral load determination during pregnancy as a possible cervical cancer risk. J Exp Clin Cancer Res 25(1): 29–38
Caluwaerts S, van Calsteren K, Mertens L, Lagae L, Moerman P, Hanssens M, Wuyts K, Vergote I, Amant F (2006) Neoadjuvant chemotherapy followed by radical hysterectomy for invasive cervical cancer diagnosed during pregnancy: report of a case and review of the literature. Int J Gynecol Cancer 16(2): 905–908
CDC. Genital HPV infection. Genital HPV infection (web site). Available at: http://www.cdc.gov/std/HPV/STDFact-HPV.htm
Chan PK, Chang AR, Tam WH, Cheung JL, Cheng AF (2002) Prevalence and genotype distribution of human cervical human papilloma virus infection: comparison between pregnant women and non-pregnant controls. J Med Virol 67(4): 583–588
Charkviani L, Charkviani T, Natenadze N, Tsitsishvili Z (2003) Cervical carcinoma and pregnancy. Clin Exp Obstet Gynecol 30(1): 19–22
Foersterling DL, Blythe JG (1999) Ovarian carcinoma, endometrial carcinoma and pregnancy. Gynecol Oncol 72(3): 425–426
Germann N, Haie-Meder C, Morice P, Lhomme C, Duvillard P, Hacene K, Gerbaulet A (2005) Management and clinical outcomes of pregnant patients with invasive cervical cancer. Ann Oncol 16(3): 397–402
Hand JW, Li Y, Thomas EL, Rutherford MA, Hajnal JV (2006) Prediction of specific absorption rate in mother and fetus associated with MRI examinations during pregnancy. Magn Reson Med 55(4): 883–893
Ichikawa Y, Takano K, Higa S, Tanabe M, Wada A, Sugita M, Tsunoda H, Nishida M (2001) Endometrial carcinoma coexisting with pregnancy, presumed to derive from adenomyosis: a case report. Int J Gynecol Cancer 11(6): 488–490
Itoh K, Shiozawa T, Shiohara S, Ashida T, Konishi I (2004) Endometrial carcinoma in a septate uterus detected 6 months after full-term delivery: case report and review of the literature Gynecol Oncol 93(1): 242–247
Jones WB, Shingleton HM, Russell A, Fremgen AM, Clive RE, Winchester DP, Chmiel JS (1996) Cervical carcinoma and pregnancy. A national patterns of care study of the American College of Surgeons. Cancer 77(8): 1479–1488
Khan MJ, Castle PE, Lorincz AT, Wacholder S, Sherman M, Scott DR, Rush BB, Glass AG, Schiffman M (2005) The elevated 10-year risk of cervical precancer and cancer in women with human papilloma (HPV) virus type 16 or 18 and the possibility of utility of type-specific HPV testing in clinical practice. J Natl Cancer Inst 97(14): 1072–1079
Kovacs AG, Cserni G (1996) Endometrial cancer in early pregnancy. Gynecol Obstet Invest 41(1): 70–72
Leunen K, Amant F, Debiec-Rychter M, Croes R, Hagemeijer A, Schoenmakers EF, Vergote I (2003) Endometrial stromal sarcoma presenting as post-partum haemorrhage: report of a case with sole t(10;17)(q22;p13) translocation. Gynecol Oncol 91(1): 265–271
Lu DW, Pirog EC, Zhu X, Wang HL, Pinto KR (2003) Prevalence and typing of HPV DNA in atypical squamous cells in pregnant women. Acta Cytol 47(6): 1008–1016
McPherson CP, Sellers TA, Potter JD, Bostick RM, Folsom AR (1996) Reproductive factors and risk of endometrial cancer: the Iowa Women’s Health study. Am J Epidemiol 143(12): 1195–1202
Munoz N, Franceschi S, Bosetti C, Moreno V, Herrero R, Smith JS, Shah KV, Meijer CJ, Bosch FX (2002). The role of parity and human papillomavirus in cervical cancer: the IARC multicentric case-control study. Lancet 359(9312): 1093–1101
Nguyen C, Montz FJ, Bristow RE (2000) Management of stage 1 cervical cancer in pregnancy. Obstet Gynecol Surv 55(10): 633–643
Ojomo EO, Ezimokhai M, Reale FR, Nwabineli NJ (1993). Recurrent post-partum haemorrhage caused by endometrial carcinoma co-existing with endometrioid carcinoma of the ovary in a full term pregnancy. Br J Obstet Gynaecol 100(5): 489–491
Schammel DP, Mittal KR, Kaplan K, Deligdisch L, Tavassoli FA (1998) Endometrial adenocarcinoma associated with intrauterine pregnancy. A report of five cases and a review of the literature. Int J Gynecol Pathol 17(4): 327–335
Schneller JA, Nicastri AD (1994) Intrauterine pregnancy coincident with endometrial cancer: a case study and review of the literature. Gynecol Oncol 54(1): 87–90
Smith EM, Johnson SR, Jiang D, Zaleski S, Lynch CF, Brundage S, Anderson RD, Turek LP (1991) The association between pregnancy and human papilloma virus prevalence. Cancer Detect Prev 15(5): 397–402
Smith LH, Danielsen B, Allen ME, Cress R (2003) Cancer associated with obstetric delivery: results of linkage with the California cancer registry Am J Obstet Gynecol 189(4): 1128–1135
Sood AK, Sorosky JI, Mayr N, Anderson B, Buller RE, Niebyl J (2000) Cervical cancer diagnosed shortly after pregnancy: prognostic variables and delivery routes. Obstet Gynecol 95(6 Pt 1): 832–838
Stan C, Megevand E, Irion O, Wang C, Bruchim I, Petignat P (2005) Cervical cancer in pregnant women: Laparoscopic evaluation before delaying treatment. Eur J Gynaecol Oncol 26(6): 649–650
Stead JA, Behnam KM (1997) Co-existing endometrial adenocarcinoma and tubal ectopic pregnancy: a case report. W V Med J 93(3): 133–135
Takushi M, Moromizato H, Sakumoto K, Kanazawa K (2002) Management of invasive carcinoma of the uterine cervix associated with pregnancy: outcome of intentional delay in treatment. Gynecol Oncol 87(2): 185–189
Vaccarello L, Apte SM, Copeland LJ, Boutselis JG, Rubin SC (1999) Endometrial carcinoma associated with pregnancy: report of three cases and review of the literature. Gynecol Oncol 74(1): 118–122
Van der Vange N, Weverling GJ, Ketting BW, Ankum WM, Samlal R, Lammes FB (1995). The prognosis of cervical cancer associated with pregnancy: a matched cohort study. Obstet Gynecol 85: 1022–1026
Victoriano MJ (1998) Endometrial carcinoma co-existing with an intrauterine pregnancy: a case report. Philipp J Obstet Gynecol 22(4): 135–146
Zemlickis D, Lishner M, Degendorfer P, Panzarella T, Sutcliffe S, Koren G. (1991) Maternal and fetal outcome after invasive cervical cancer in pregnancy. J Clin Oncol 9(11): 1956–1961
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Kehoe, S. (2008). Cervical and Endometrial Cancer During Pregnancy. In: Cancer and Pregnancy. Recent Results in Cancer Research, vol 178. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-71274-9_7
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DOI: https://doi.org/10.1007/978-3-540-71274-9_7
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