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Pharmaceutical Potential of Marine Fungal Endophytes

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Endophytes and Secondary Metabolites

Part of the book series: Reference Series in Phytochemistry ((RSP))

Abstract

The marine environment is currently well explored as one of the most essential sources regarding to natural products in research, since organisms from oceans have exhibited exceptional biological, biochemical, and biosynthetic potential. Similarly, microorganisms’ natural products represent a substantial area for novel therapeutic compounds search. Many reviews highlighted microbial metabolites as targets for discovery and development of new drugs, especially anticancer, antibiotics, antifungals, and antiparasitics among others. Marine fungal endophytes are therefore virtually unlimited sources of novel compounds with numerous potential therapeutic applications due to their immense diversity and proven ability to produce natural products of medicinal and pharmaceutical importance, thus inspiring researchers to further study them. This book chapter reviews some of the endophytic fungi isolated from marine sources that produce metabolites with various biological activities against human pathogenic microorganisms. The potential for the exploitation in the pharmaceutical industry and concerns are also discussed.

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Authors and Affiliations

  1. Department of Health Sciences, Faculty of Science, University of Mauritius, Moka, Mauritius

    Rajesh Jeewon, Amiirah Bibi Luckhun, Nabeelah B. Sadeer & Mohamad Fawzi Mahomoodally

  2. Faculty of Agriculture, University of Mauritius, Réduit, Mauritius

    Vishwakalyan Bhoyroo, Sillma Rampadarath & Daneshwar Puchooa

  3. Department of Biotechnology, School of Life Sciences, Pondicherry University, Pondicherry, India

    V. Venkateswara Sarma

  4. Department of Microbiology, School of Life Sciences, Central University of Tamil Nadu, Thiruvarur, India

    Siva Sundara Kumar Durairajan

  5. Center of Excellence in Fungal Research, Mae Fah Luang University, Chiang Rai, Thailand

    Kevin D. Hyde

Authors
  1. Rajesh Jeewon
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  2. Amiirah Bibi Luckhun
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  3. Vishwakalyan Bhoyroo
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  4. Nabeelah B. Sadeer
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  5. Mohamad Fawzi Mahomoodally
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  6. Sillma Rampadarath
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  7. Daneshwar Puchooa
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  8. V. Venkateswara Sarma
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  9. Siva Sundara Kumar Durairajan
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  10. Kevin D. Hyde
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Corresponding author

Correspondence to Rajesh Jeewon .

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Editors and Affiliations

  1. Department of Botany, University of Calcutta, Kolkata, West Bengal, India

    Sumita Jha

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Jeewon, R. et al. (2019). Pharmaceutical Potential of Marine Fungal Endophytes. In: Jha, S. (eds) Endophytes and Secondary Metabolites. Reference Series in Phytochemistry. Springer, Cham. https://doi.org/10.1007/978-3-319-90484-9_6

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