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Consequences of Altered Cardiac Activity on Brain Activity

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Abstract

Many heart diseases can affect brain activity and the most common are atrial fibrillation, arterial hypertension, heart failure, ischemic heart disease, valvular heart disease, pulmonary arterial hypertension, and sudden cardiac arrest. The mechanisms underlying the brain dysfunction and the cognitive impairment can be different depending on the heart disease, but the decreased blood perfusion, silent cerebral infarctions due to cardioembolism, and cerebral white matter hyperintensities are the most commonly involved pathogenetic mechanisms, although also genetics seems to play a role in many diseases. Another important aspect to be considered is the presence of depression, which is common in many heart diseases and can affect not only the quality of life but also the outcome. Considering the importance of brain dysfunction on outcome, it is evident from the literature, how important it is to correctly identify patients who develop this type of problem in order to optimize their treatment and improve their outcome.

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Authors and Affiliations

  1. Department of Molecular Medicine, Section of Cardiology, University of Pavia, Pavia, Italy

    Enrico Baldi

  2. Cardiac Intensive Care Unit, Arrhythmia and Electrophysiology and Experimental Cardiology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy

    Enrico Baldi & Simone Savastano

  3. Division of Cardiology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy

    Enrico Baldi & Simone Savastano

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  1. Enrico Baldi
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  2. Simone Savastano
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Correspondence to Enrico Baldi .

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Editors and Affiliations

  1. Dept of Drug Sciences, Pharmacology Sect, University of Pavia, Dept of Drug Sciences, Pharmacology Sect, Pavia, Pavia, Italy

    Stefano Govoni

  2. Dept of Brain and Behavioural Sciences, University of Pavia Dept of Brain and Behavioural Sciences, Pavia, Pavia, Italy

    Pierluigi Politi

  3. Department of Molecular Medicine, University of Pavia, Department of Molecular Medicine, Pavia, Pavia, Italy

    Emilio Vanoli

Section Editor information

  1. Dipartimento di Medicina Clinica e Sperimentale, Unità di Psichiatria, Università degli Studi di Catania, Catania, Italy

    Laura Fusar-Poli

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Baldi, E., Savastano, S. (2019). Consequences of Altered Cardiac Activity on Brain Activity. In: Govoni, S., Politi, P., Vanoli, E. (eds) Brain and Heart Dynamics. Springer, Cham. https://doi.org/10.1007/978-3-319-90305-7_13-1

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