Skip to main content
SpringerLink
Log in
Book cover

Oncologic Critical Care pp 1–6Cite as

Blood Components

  • Living reference work entry
  • First Online:

Abstract

The collection of blood from volunteer donors is done manually and also by automated apheresis devices. Donors are given relevant information about the collection process and testing performed and sign a consent form. If the donor is qualified to donate, a collection is performed, and the unit may be further processed to obtain red cells, plasma, and platelets following strict good manufacturing practices if the donation was whole blood. Testing for RBC alloantibodies, ABO type, and infectious diseases is performed; other testing such as HLA and neutrophil antibodies may be added. Units are stored at determined conditions and transfused as appropriate. Modifications such as leukoreduction, irradiation, and washing are performed routinely or according to clinical need.

This is a preview of subscription content, log in via an institution.

References

  1. Auten JD, Lunceford NL, Horton JL, Galarneau MR, Galindo RM, Shepps CD, Zieber TJ, Dewing CB. The safety of early fresh, whole blood transfusion among severely battle injured at US marine corps forward surgical care facilities in Afghanistan. J Trauma Acute Care Surg. 2015;79:790–6.

    Article  Google Scholar 

  2. Berzuini A, Spreafico M, Prati D. One size doesn’t fit all: should we reconsider the introduction of cold-stored platelets in blood bank inventories? F1000Res. 2017;6:95.

    Article  Google Scholar 

  3. Ellingson KD, Sapiano MRP, Haass KA, Savinkina AA, Baker ML, Chung KW, Henry RA, Berger JJ, Kuehnert MJ, Basavaraju SV. Continued decline in blood collection and transfusion in the United States-2015. Transfusion. 2017;57(Suppl 2):1588–98.

    Article  Google Scholar 

  4. Freireich EJ, Lichtiger B, Mattiuzzi G, Martinez F, Reddy V, Kyle Wathen J. A prospective, randomized, double-blind study, comparing unirradiated to irradiated white blood cell transfusions in acute leukemia patients. Leukemia. 2012;27:861.

    Article  Google Scholar 

  5. Price TH, Boeckh M, Harrison RW, McCullough J, Ness PM, Strauss RG, Nichols WG, Hamza TH, Cushing MM, King KE, Young JA, Williams E, McFarland J, Holter Chakrabarty J, Sloan SR, Friedman D, Parekh S, Sachais BS, Kiss JE, Assmann SF. Efficacy of transfusion with granulocytes from G-CSF/dexamethasone-treated donors in neutropenic patients with infection. Blood. 2015;126:2153–61.

    Article  CAS  Google Scholar 

  6. Spinella PC, Pidcoke HF, Strandenes G, Hervig T, Fisher A, Jenkins D, Yazer M, Stubbs J, Murdock A, Sailliol A, Ness PM, Cap AP. Whole blood for hemostatic resuscitation of major bleeding. Transfusion. 2016;56(Suppl 2):S190–202.

    Article  Google Scholar 

  7. Standards for Blood Banks and Transfusion Services. 31st ed. Bethesda: AABB; 2018.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Laboratory Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA

    Fernando Martinez & Faysal Fedda

Authors
  1. Fernando Martinez
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Faysal Fedda
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Fernando Martinez .

Editor information

Editors and Affiliations

  1. Department of Critical Care, University of Texas MD Anderson Cancer C Department of Critical Care, Houston, TX, USA

    Joseph L. Nates

  2. Department of Critical Care, University of Texas MD Anderson Cancer C Department of Critical Care, Houston, TX, USA

    Kristen J. Price

Rights and permissions

Reprints and permissions

Copyright information

© 2019 Springer Nature Switzerland AG

About this entry

Check for updates. Verify currency and authenticity via CrossMark

Cite this entry

Martinez, F., Fedda, F. (2019). Blood Components. In: Nates, J., Price, K. (eds) Oncologic Critical Care. Springer, Cham. https://doi.org/10.1007/978-3-319-74698-2_201-1

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-74698-2_201-1

  • Received:

  • Accepted:

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-74698-2

  • Online ISBN: 978-3-319-74698-2

  • eBook Packages: Springer Reference MedicineReference Module Medicine

Publish with us

Policies and ethics

Search

Navigation