Definition
The stem cell theory of aging claims that the aging process is the result of the inability of various types of resident tissue stem cells to continue to replenish the tissues of an organism with functional differentiated cells, capable of maintaining that tissue’s original function. Therefore, stem cell aging, a subcategory of cellular theories of aging, is defined as a deficit of stem cells to replace the harmed tissue cells due to the decrease in the totality of tissue resident stem cells and/or their regenerative potential.
Overview
Aging is a complex biological process accompanied by a progressive decrease in the organism’s capacity to maintain physiological organ homeostasis, culminating in...
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Lazarovici, P. (2019). Stem Cells Aging. In: Gu, D., Dupre, M. (eds) Encyclopedia of Gerontology and Population Aging. Springer, Cham. https://doi.org/10.1007/978-3-319-69892-2_432-1
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DOI: https://doi.org/10.1007/978-3-319-69892-2_432-1
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