Overview
Is aging a cause of cancer or cancer a cause of aging? Here the evolutionary connections between aging and cancer are debated, and it is shown that cancer is an unlikely evolutionary cause of aging.
Nowadays aging is explained in two completely opposite ways. The first (non-programmed aging paradigm) explains aging as something not determined by adaptive necessities but due to the progressive accumulation of the effects of many degenerative phenomena. The second (programmed aging paradigm) explains aging as an adaptive phenomenon and therefore genetically determined and regulated.
One of the main differences between the two interpretations is that programmed aging paradigm predicts the existence of specific genetically programmed mechanisms that determine aging, and indeed these mechanisms are absolutely necessary to admit the possible validity of this thesis. On the contrary, the non-programmed aging paradigm does...
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Libertini, G. (2019). Aging and Cancer. In: Gu, D., Dupre, M. (eds) Encyclopedia of Gerontology and Population Aging. Springer, Cham. https://doi.org/10.1007/978-3-319-69892-2_26-1
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DOI: https://doi.org/10.1007/978-3-319-69892-2_26-1
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Latest
Aging and Cancer- Published:
- 09 August 2019
DOI: https://doi.org/10.1007/978-3-319-69892-2_26-2
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Original
Aging and Cancer- Published:
- 07 May 2019
DOI: https://doi.org/10.1007/978-3-319-69892-2_26-1