Dickkopf 3

Nakamura, Rei; Hackam, Abigail S.

doi:10.1007/978-3-319-67199-4_101983

Rei Nakamura² &
Abigail S. Hackam³

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References

Barrantes Idel B, Montero-Pedrazuela A, Guadano-Ferraz A, Obregon MJ, Martinez de Mena R, Gailus-Durner V, et al. Generation and characterization of dickkopf3 mutant mice. Mol Cell Biol. 2006;26:2317–26.
Article CAS PubMed Google Scholar
Dellinger TH, Planutis K, Jandial DD, Eskander RN, Martinez ME, Zi X, et al. Expression of the Wnt antagonist Dickkopf-3 is associated with prognostic clinicopathologic characteristics and impairs proliferation and invasion in endometrial cancer. Gynecol Oncol. 2012;126:259–67.
Article PubMed PubMed Central CAS Google Scholar
Fukusumi Y, Meier F, Gotz S, Matheus F, Irmler M, Beckervordersandforth R, et al. Dickkopf 3 promotes the differentiation of a rostrolateral midbrain dopaminergic neuronal subset in vivo and from pluripotent stem cells in vitro in the mouse. J Neurosci: Off J Soc Neurosci. 2015;35:13385–401.
Article CAS Google Scholar
Fung KY, Tabor B, Buckley MJ, Priebe IK, Purins L, Pompeia C, et al. Blood-based protein biomarker panel for the detection of colorectal cancer. PLoS One. 2015;10:e0120425.
Article PubMed PubMed Central CAS Google Scholar
Glinka A, Wu W, Delius H, Monaghan AP, Blumenstock C, Niehrs C. Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction. Nature. 1998;391:357–62.
Article PubMed CAS Google Scholar
Lu D, Bao D, Dong W, Liu N, Zhang X, Gao S, et al. Dkk3 prevents familial dilated cardiomyopathy development through Wnt pathway. Lab Investig; J Tech Methods Pathol. 2016;96:239–48.
Article CAS Google Scholar
Ludwig J, Federico G, Prokosch S, Kublbeck G, Schmitt S, Klevenz A, et al. Dickkopf-3 acts as a modulator of B cell fate and function. J Immunol. 2015;194:2624–34.
Article PubMed CAS Google Scholar
Meister M, Papatriantafyllou M, Nordstrom V, Kumar V, Ludwig J, Lui KO, et al. Dickkopf-3, a tissue-derived modulator of local T-cell responses. Front Immunol. 2015;6:78.
Article PubMed PubMed Central CAS Google Scholar
Monaghan AP, Kioschis P, Wu W, Zuniga A, Bock D, Poustka A, et al. Dickkopf genes are co-ordinately expressed in mesodermal lineages. Mech Dev. 1999;87:45–56.
Article CAS PubMed Google Scholar
Nakamura RE, Hackam AS. Analysis of Dickkopf3 interactions with Wnt signaling receptors. Growth Factors. 2010;28:232–42.
Article PubMed PubMed Central CAS Google Scholar
Nakamura RE, Hunter DD, Yi H, Brunken WJ, Hackam AS. Identification of two novel activities of the Wnt signaling regulator Dickkopf 3 and characterization of its expression in the mouse retina. BMC Cell Biol. 2007;8:52.
Article PubMed PubMed Central CAS Google Scholar
Papatriantafyllou M, Moldenhauer G, Ludwig J, Tafuri A, Garbi N, Hollmann G, et al. Dickkopf-3, an immune modulator in peripheral CD8 T-cell tolerance. Proc Natl Acad Sci U S A. 2012;109:1631–6.
Article PubMed PubMed Central Google Scholar
Tsuji T, Miyazaki M, Sakaguchi M, Inoue Y, Namba M. A REIC gene shows down-regulation in human immortalized cells and human tumor-derived cell lines. Biochem Biophys Res Commun. 2000;268:20–4.
Article PubMed CAS Google Scholar
Veeck J, Dahl E. Targeting the Wnt pathway in cancer: the emerging role of Dickkopf-3. Biochim Biophys Acta. 2012;1825:18–28.
PubMed CAS Google Scholar
Wang Z, Lin L, Thomas DG, Nadal E, Chang AC, Beer DG, et al. The role of Dickkopf-3 overexpression in esophageal adenocarcinoma. J Thorac Cardiovasc Surg. 2015;150:377–85 .e2
Article PubMed PubMed Central CAS Google Scholar
Zenzmaier C, Hermann M, Hengster P, Berger P. Dickkopf-3 maintains the PANC-1 human pancreatic tumor cells in a dedifferentiated state. Int J Oncol. 2012;40:40–6.
PubMed CAS Google Scholar
Zhang Y, Liu Y, Zhu XH, Zhang XD, Jiang DS, Bian ZY, et al. Dickkopf-3 attenuates pressure overload-induced cardiac remodelling. Cardiovasc Res. 2014;102:35–45.
Article PubMed PubMed Central CAS Google Scholar
Zhang J, Gotz S, Vogt Weisenhorn DM, Simeone A, Wurst W, Prakash N. A WNT1-regulated developmental gene cascade prevents dopaminergic neurodegeneration in adult En1(+/−) mice. Neurobiol Dis. 2015;82:32–45.
Article PubMed CAS Google Scholar

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Authors and Affiliations

Spark Therapeutics, 3737 Market Street, Suite 1300, Philadelphia, PA, 19104, USA
Rei Nakamura
Bascom Palmer Eye Institute, University of Miami, Miami, FL, 33136, USA
Abigail S. Hackam

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Rei Nakamura
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Abigail S. Hackam
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Correspondence to Abigail S. Hackam .

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Editors and Affiliations

Department of Molecular Science and Technology, Ajou University, Suwon, Korea
Sangdun Choi

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Nakamura, R., Hackam, A.S. (2018). Dickkopf 3. In: Choi, S. (eds) Encyclopedia of Signaling Molecules. Springer, Cham. https://doi.org/10.1007/978-3-319-67199-4_101983

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DOI: https://doi.org/10.1007/978-3-319-67199-4_101983
Published: 01 June 2018
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-67198-7
Online ISBN: 978-3-319-67199-4
eBook Packages: Biomedical and Life SciencesReference Module Biomedical and Life Sciences

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