Skip to main content
SpringerLink
Log in

Transient Receptor Potential Cation Channel, Subfamily C, Member 2, Pseudogene

  • Reference work entry
  • First Online:
Book cover Encyclopedia of Signaling Molecules

  • 216 Accesses

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 4,499.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 4,499.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Birnbaumer L. The TRPC class of ion channels: a critical review of their roles in slow sustained increases in intracellular Ca2+ concentrations. Annu Rev Pharmacol Toxicol. 2009;49:395–426.

    Article  PubMed  CAS  Google Scholar 

  • Brann JH, Dennis JC, Morrisin EF, Fadool DA. Type-specific inositol 1,4,5-trisphosphate receptor localization in the vomeronasal organ and its interaction with a transient receptor potential channel, TRPC2. J Neurochem. 2002;83:1452–60.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Dulac C, Torello AT. Molecular detection of pheromone signals in mammals: from genes to behaviour. Nat Rev Neurosci. 2003;7:551–62.

    Article  CAS  Google Scholar 

  • Hohenbrink P, Dempewolf S, Zimmermann E, Mundy NI, Radespiel U. Functional promiscuity in mammalian chemosensory system: extensive expression of vomeronasal receptors in the main olfactory epithelium of mouse lemurs. Front Neuroanat. 2014;8:102.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Huang GN, Zeng W, Kim JY, Yan JP, Han L, Muallem S, et al. STIM1 carboxyl-terminus activates native SOC I (CRAC) and TRPC1 channels. Nat Cell Biol. 2006;8:1003–10.

    Article  PubMed  CAS  Google Scholar 

  • Kiemnec-Tyburczy KM, Woodley SK, Watts RA, Arnold SJ, Houck LD. Expression of vomeronasal receptors and related signaling molecules in the nasal cavity of a caudate amphibian (Plethodon shermani). Chem Senses. 2012;37:335–46. doi:10.1093/chemse/bjr105.

    Article  PubMed  CAS  Google Scholar 

  • Liman ER, Corey DP, Dulac C. TRP2: a candidate transduction channel for mammalian pheromone sensory signaling. Proc Natl Acad Sci U S A. 1999;96:5791–6.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Lucas P, Ukhanov K, Leinders-Zufall T, Zufall F. A diacylglycerol-gated cation channel in vomeronasal neuron dendrites is impaired in TRPC2 mutant mice: mechanism of pehromone transduction. Neuron. 2003;40:551–61.

    Article  PubMed  CAS  Google Scholar 

  • Miller BA. TRPC2. In: Nilius B, Flockerzi V, editors. Mammalian transient potential (TRP) cation channels. Berlin/Heidelberg: Springer; 2014. p. 53–65.

    Chapter  Google Scholar 

  • Sansone A, Syed AS, Tantalaki E, Korsching SI, Manzini I. Trpc2 is expressed in two olfactory subsystems, the main and the vomeronasal system of larval Cenpus laevis. J Exp Biol. 2014;217:2235–8.

    Article  PubMed  PubMed Central  Google Scholar 

  • Sato Y, Miyasaka N, Yoshihara Y. Mutually exclusive glomerular innervation by two distincy types of olfactory sensory neurons revealed in transgenic zebrafish. J Neurosci. 2005;25:4889–97.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Stamboulian S, Moutin MJ, Treves S, Pochon N, Grunwald D, Zorzato F, et al. Junctate, an inosotol 1,4,5-triphosphate receptor associated protein, is present in rodent sperm and binds TRPC2 and TRPC5 but not TRPC1 channels. Dev Biol. 2005;286:326–37.

    Article  PubMed  CAS  Google Scholar 

  • Stowers L, Holy TE, Meister M, Dulac C, Koentges G. Loss of sex discrimination and male-male aggression in mice deficient for trp2. Science. 2002;295:1493–500.

    Article  PubMed  CAS  Google Scholar 

  • Sutton KA, Jungenickel MK, Wang Y, Cullen K, Lambert S, Florman HM. Enkurin is a novel calmodulin and TRPC channel biinding protein in sperm. Dev Biol. 2004;274:426–35.

    Article  PubMed  CAS  Google Scholar 

  • Tang J, Lin Y, Zhang Z, Tikunov S, Birnbaumer L, Zhu MX. Identification of common binding sites for calmodulin and inositol 1,4,5-trisphosphate receptors on the carboxy termini of trp channnels. J Biol Chem. 2001;276:21303–10.

    Article  PubMed  CAS  Google Scholar 

  • Törnquist K, Sukumar P, Kemppainen K, Löf C, Viitanen T. Canonical tansient receptor potential channel 2 (TRPC2): old name-new games. Importance in regulating of rat thyroid cell physiology. Pflugers Arch. 2014;466:2025–34.

    Article  PubMed  CAS  Google Scholar 

  • Yildirim E, Birnbaumer L. TRPC2: molecular biology and functional importance. Handb Exp Pharmacol. 2007;179:51–73.

    Google Scholar 

  • Yu RC. TRICK or TRP? What Trpc2−/− mice tell us about vomeronasal organ mediated innate behaviors. Front Neurosci. 2015;9:221.

    Article  PubMed  PubMed Central  Google Scholar 

  • Yuan JP, Kiselyov K, Shin DM, Chen J, Shcheynikov N, Schwar MK, et al. Homer binds TRPC family channels and is required for gating of TRPC1 by IP3 receptors. Cell. 2003;114:777–89.

    Article  PubMed  CAS  Google Scholar 

  • Zufall F. TRPs in olfaction. In: Nilius B, Flockerzi V, editors. Mammalian transient potential (TRP) cation channels. Berlin/Heidelberg: Springer; 2014. p. 918–33.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Cell Biology, Faculty of Science and Engineering, Åbo Akademi University, 20520, Turku, Finland

    Kid Törnquist & Kati Kemppainen

  2. Minerva Foundation institute for Medical Research, 00290, Helsinki, Finland

    Kid Törnquist

Authors
  1. Kid Törnquist
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Kati Kemppainen
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Kid Törnquist .

Editor information

Editors and Affiliations

  1. Department of Molecular Science and Technology, Ajou University, Suwon, Korea

    Sangdun Choi

Rights and permissions

Reprints and permissions

Copyright information

© 2018 Springer International Publishing AG

About this entry

Check for updates. Verify currency and authenticity via CrossMark

Cite this entry

Törnquist, K., Kemppainen, K. (2018). Transient Receptor Potential Cation Channel, Subfamily C, Member 2, Pseudogene. In: Choi, S. (eds) Encyclopedia of Signaling Molecules. Springer, Cham. https://doi.org/10.1007/978-3-319-67199-4_101945

Download citation

Publish with us

Policies and ethics

Search

Navigation