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Exposure to Microbiological Agents in Indoor and Occupational Environments pp 191–212Cite as

Human Biomonitoring of Mycotoxins for the Detection of Nutritional, Environmental and Occupational Exposure

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Abstract

The development of methods for the detection of mycotoxins as biomarker for nutritional, environmental, and occupational exposure is reviewed in this chapter. Summaries on the current state of research on mycotoxin metabolism of aflatoxins, deoxynivalenol, fumonisins, ochratoxins, and zearalenone are given. Furthermore, the development of biomarkers from these studies is discussed and excretion rates are reported. Starting from single analyte methods such as for aflatoxin M1, the first mycotoxin biomarker for aflatoxin exposure, the improvement of detection methods for aflatoxins, ochratoxin A, zearalenone, deoxynivalenol, fumonisins, and many other mycotoxins up to the recent HPLC-MS/MS methods is shown. Finally, the recently developed multi-mycotoxin methods for the detection of a broad spectrum of biomarkers and fungal metabolites is depicted and their current applications and future perspectives are discussed.

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  1. Westfälische Wilhelms-Universität Münster, Institute of Food Chemistry, Münster, Germany

    Benedikt Cramer & Hans-Ulrich Humpf

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  1. Benedikt Cramer
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  2. Hans-Ulrich Humpf
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Correspondence to Benedikt Cramer .

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Editors and Affiliations

  1. Lisbon School of Health Technology Environment and Health RG, Polytechnic Institute of Lisbon, Lisbon, Portugal

    Carla Viegas

  2. Lisbon School of Health Technology Environment and Health RG, Polytechnic Institute of Lisbon, Lisbon, Portugal

    Susana Viegas

  3. Lisbon School of Health Technology Polytechnic Institute of Lisbon, University of Lisbon, Lisbon, Portugal

    Anita Gomes

  4. Department Health Protection, National Institute for Health & Welfare, Kuopio, Finland

    Martin Täubel

  5. National Health Institute Portugal, Lisbon, Portugal

    Raquel Sabino

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Cramer, B., Humpf, HU. (2017). Human Biomonitoring of Mycotoxins for the Detection of Nutritional, Environmental and Occupational Exposure. In: Viegas, C., Viegas, S., Gomes, A., Täubel, M., Sabino, R. (eds) Exposure to Microbiological Agents in Indoor and Occupational Environments. Springer, Cham. https://doi.org/10.1007/978-3-319-61688-9_9

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