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Fungal and Parasitic Infections

Clinical and Neuroimaging Features

Book cover Clinical Neuroradiology

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Abstract

Parasitic and fungal infections of the central nervous system (CNS) can cause significant morbidity or mortality, and risk factors include immunodeficiency and living in endemic areas. Neuroimaging studies play a critical role in the diagnosis and clinical assessment of these patients. This chapter discusses the most common patterns of magnetic resonance imaging (MRI) found in parasitic and fungal infections.

This publication is endorsed by: European Society of Neuroradiology (www.esnr.org).

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Abbreviations

3D-TOF:

Three-dimensional time of flight

ADC:

Apparent diffusion coefficient

AIDS:

Acquired immunodeficiency syndrome

ASL:

Arterial spin label

CISS:

Constructive interference steady state

CNS:

Central nervous system

CSF:

Cerebrospinal fluid

CT:

Computed tomography

DCE:

Dynamic contrast enhanced

DSC:

Dynamic susceptibility contrast

DWI:

Diffusion-weighted imaging

FIESTA:

Fast imaging employing steady-state acquisition

FLAIR:

Fluid attenuation inversion recovery

HAT:

Human African trypanosomiasis

HIV:

Human immunodeficiency virus

MRI:

Magnetic resonance imaging

MRS:

Magnetic resonance imaging spectroscopy

NC:

Neurocysticercosis

NECT:

Nifurtimox-eflornithine combination therapy

PAM:

Primary amebic meningoencephalitis

PAM:

Primary amebic meningoencephalitis

SPECT:

Single photon emission computed tomography

SWI:

Susceptibility-weighted imaging

WI:

Weighted images

References

  • Abdel Rasek AA, Watcharakorn A, Castillo M. Parasitic diseases of the central nervous system. Neuroimaging Clin N Am. 2011;21(4):815–41.

    Article  Google Scholar 

  • Akgoz A, Mukundan S, Lee TC. Imaging of rickettsial, spirochetal, and parasitic infections. Neuroimaging Clin N Am. 2012:22(4):633–57

    Article  Google Scholar 

  • Carpio A, Romod ML, Parkhousef RME, Shortg B, Duag T. Parasitic diseases of the central nervous system: lessons for clinicians and policy makers. Expert Rev Neurother. 2016;16(4):401–14.

    Article  CAS  Google Scholar 

  • Carpio A, Fleury A, Romo ML, Abraham R. Neurocysticercosis: the good, the bad, and the missing. Expert Rev Neurother. 2018;18(4):289–301.

    Article  CAS  Google Scholar 

  • Del Brutto OH, et al. Revised diagnostic criteria for neurocysticercosis. J Neurol Sci. 2017;15(372):202–10.

    Article  Google Scholar 

  • Hanagandi, et al. Multidisciplinary approach to tropical and subtropical infectious diseases: imaging with pathologic correlation. Neurographics. 2015;5(21):258–78.

    Article  Google Scholar 

  • Kimura-Hayama, et al. Neurocysticercosis: radiologic-pathologic correlation. Radiographies. 2010;30(6):1705–19.

    Article  Google Scholar 

  • Lury KM, Castillo M. Chagas’ disease involving the brain and spinal cord: MRI findings. AJR Am J Roentgenol. 2005;185(2):550–2.

    Article  Google Scholar 

  • Palacios E, Rojas R, Rodulfa J, Gonzalez-Toledo E. Magnetic resonance imaging in fungal infections of the brain. Top Magn Reson Imaging. 2014;23(3):199–212.

    Article  Google Scholar 

  • Rasalkar DD, Paunipagar BK, Sanghvi D, Sonawane BD, Loniker P. Magnetic resonance imaging in cerebral malaria: a report of four cases. Br J Radiol. 2011;84(1000):380–5.

    Article  CAS  Google Scholar 

  • Razek AAA, Watcharakorn A, Castillo M. Parasitic diseases of the central nervous system. Neuroimaging Clin N Am, 2011;21(4): 815–41, viii.

    Google Scholar 

  • Rocha AJ, et al. Granulomatous diseases of the central nervous system. Top Magn Reson Imaging. 2005;16(2):155–87.

    Article  Google Scholar 

  • Safder S, Carpenter JS, Roberts TD, Bailey N. The “Black Turbinate” sign: an early MR imaging finding of nasal mucormycosis. AJNR Am J Neuroradiol. 2010;31:771–4.

    Article  CAS  Google Scholar 

  • Saleem S, Belal AI, El-Ghandour NM. Spinal cord schistosomiasis: MR imaging appearance with surgical and pathologic correlation. AJNR Am J Neuroradiol. 2005;26(7):1646–54.

    PubMed  Google Scholar 

  • Shih RY, Koeller KK. Bacterial, fungal, and parasitic infections of the central nervous system: radiologic-pathologic correlation and historical. Perspectives. 2015;35(4):1141–69.

    Google Scholar 

  • Singh P, et al. Amebic meningoencephalitis: spectrum of imaging findings. AJNR Am J Neuroradiol. 2006;27(6):1217–21.

    CAS  PubMed  Google Scholar 

  • Smith AB, Smirniotopoulos JG, Rushing EJ. From the archives of the AFIP: central nervous system infections associated with human immunodeficiency virus infection: radiologic-pathologic correlation. Radiographics. 2008;28(7):2033–58.

    Article  Google Scholar 

  • Starkey J, Moritani T, Kirby P. MRI of CNS fungal infections: review of aspergillosis to histoplasmosis and everything in between. Clin Neuroradiol. 2014;24(3):217–30.

    Article  CAS  Google Scholar 

  • Therekathu J, et al. Imaging features of rhinocerebral mucormycosis: a study of 43 patients. Egypt J Radiol Nucl Med. 2018;49:447–52.

    Article  Google Scholar 

  • Venkat B, Aggarwal N, Makhaik S, Sood R. A comprehensive review of imaging findings in human cysticercosis. Jpn J Radiol. 2016;34(4):241–57.

    Article  Google Scholar 

  • Walker MD, Zunt JR. Neuroparasitic infections: cestodes, trematodes, and protozoans. Semin Neurol. 2005;25(3):262–77.

    Article  CAS  Google Scholar 

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Author information

Authors and Affiliations

  1. Hcor - Hospital do Coração, São Paulo, Brazil

    Tomás Freddi

  2. Neuroradiology Section, Hospital das Clínicas- HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, Brazil

    Laiz Laura de Godoy

  3. Neuroradiology Department, Children’s Hospital of Brasília, Brasília, DF, Brazil

    Fabricio Guimaraes Goncalves

  4. Neuroradiology division, Children’s Hospital of Philadelphia, Philadelphia, PA, USA

    César Augusto Alves

  5. Department of Diagnostic Imaging, Division of Pediatric Neuroradiology, Sidra Medical and Research Center, Doha, Qatar

    Prasad Hanagandi

Authors
  1. Tomás Freddi
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  2. Laiz Laura de Godoy
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  3. Fabricio Guimaraes Goncalves
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  4. César Augusto Alves
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  5. Prasad Hanagandi
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Corresponding author

Correspondence to Tomás Freddi .

Editor information

Editors and Affiliations

  1. Radiology and Nuclear Medicine, VU University Medical Center, Amsterdam, The Netherlands

    Frederik Barkhof

  2. National Hosp.f Neurology & Neurosurgery, UCL National Hosp.f Neurology & Neurosurgery, London, UK

    Rolf Jager

  3. Division of Neuroradiology, University Hospital Vienna Division of Neuroradiology, Wien, Austria

    Majda Thurnher

  4. Department of Neuroradiology, Hospital Vall d’Hebrón Department of Neuroradiology, Barcelona, Spain

    Alex Rovira Cañellas

Section Editor information

  1. Department for Diagnostic Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria

    Majda M. Thurnher

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Freddi, T., de Godoy, L.L., Goncalves, F.G., Alves, C.A., Hanagandi, P. (2019). Fungal and Parasitic Infections. In: Barkhof, F., Jager, R., Thurnher, M., Rovira Cañellas, A. (eds) Clinical Neuroradiology. Springer, Cham. https://doi.org/10.1007/978-3-319-61423-6_47-1

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  • DOI: https://doi.org/10.1007/978-3-319-61423-6_47-1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-61423-6

  • Online ISBN: 978-3-319-61423-6

  • eBook Packages: Springer Reference MedicineReference Module Medicine

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Chapter history

  1. Latest

    Fungal and Parasitic Infections
    Published:
    22 June 2019

    DOI: https://doi.org/10.1007/978-3-319-61423-6_47-2

  2. Original

    Fungal and Parasitic Infections
    Published:
    29 April 2019

    DOI: https://doi.org/10.1007/978-3-319-61423-6_47-1

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