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Alternative Treatments for Local Anesthetic Systemic Toxicity: Therapeutic Hypothermia After Bupivacaine-Induced Cardiac Arrest

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Challenging Cases and Complication Management in Pain Medicine

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Abstract

Ultrasound-guided peripheral nerve blocks have revolutionized regional anesthesia. Considered safe, regional anesthetic procedures still can be complicated after accidental intravascular injection of local anesthetic. The devastating effects have been described as local anesthetic systemic toxicity (LAST). The preferred antidote is intravascular lipid emulsion. Therapeutic hypothermia which protects neurological and cardiac function also may offer benefit in LAST, especially in situation where the lipid emulsion is not readily available such as in remote locations and frontline combat hospitals.

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Authors and Affiliations

  1. Department of Anesthesia and Critical Care, University of Chicago Medical Center, Chicago, IL, USA

    Shaan Sudhakaran M.D. & Magdalena Anitescu M.D., Ph.D.

Authors
  1. Shaan Sudhakaran M.D.
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  2. Magdalena Anitescu M.D., Ph.D.
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Corresponding author

Correspondence to Magdalena Anitescu M.D., Ph.D. .

Editor information

Editors and Affiliations

  1. Department of Anesthesia and Critical Care, University of Chicago Medicine, Chicago, Illinois, USA

    Magdalena Anitescu

  2. Department of Anesthesiology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, USA

    Honorio T. Benzon

  3. Division of Pain Medicine, Department of Anesthesiology, University of California San Diego School of Medicine, La Jolla, California, USA

    Mark S. Wallace

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Sudhakaran, S., Anitescu, M. (2018). Alternative Treatments for Local Anesthetic Systemic Toxicity: Therapeutic Hypothermia After Bupivacaine-Induced Cardiac Arrest. In: Anitescu, M., Benzon, H., Wallace, M. (eds) Challenging Cases and Complication Management in Pain Medicine. Springer, Cham. https://doi.org/10.1007/978-3-319-60072-7_8

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  • DOI: https://doi.org/10.1007/978-3-319-60072-7_8

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-60070-3

  • Online ISBN: 978-3-319-60072-7

  • eBook Packages: MedicineMedicine (R0)

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