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Dose Quantification in UV Phototherapy

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Book cover Ultraviolet Light in Human Health, Diseases and Environment

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 996))

Abstract

Ultraviolet light has long been used to alleviate a number of skin conditions, and its efficacy is well known. However, over-exposure to ultraviolet radiation has a number of detrimental effects and thus it is vital to maintain a dose to skin within the therapeutic window. To maximise treatment gain whilst circumventing potential side-effects of over-exposure requires accurate determination of irradiance and skin-dose. This is complicated by the fact that ultraviolet radiation is essentially absorbed at the skin surface, which means that changing orientation of the patient and source can modulate dose received. In addition, irregular patient shapes mean dose must be carefully calibrated. This chapter focuses on methods of determination of dose, clinical protocols for quantifying radiation dose received and mathematical models for estimating these quantities.

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Author information

Authors and Affiliations

  1. Cancer Research UK/MRC Oxford Institute for Radiation Oncology, Gray Laboratory, University of Oxford, Old Road Campus Research Building, Off Roosevelt Drive, Oxford, OX3 7DQ, UK

    David Robert Grimes

  2. Centre for Advanced and Interdisciplinary Radiation Research (CAIRR), School of Mathematics and Physics, Queen’s University Belfast, Belfast, UK

    David Robert Grimes

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  1. David Robert Grimes
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Correspondence to David Robert Grimes .

Editor information

Editors and Affiliations

  1. Faculty of Science and Technology, Nottingham Trent University, Nottingham, United Kingdom

    Shamim I. Ahmad

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Grimes, D.R. (2017). Dose Quantification in UV Phototherapy. In: Ahmad, S. (eds) Ultraviolet Light in Human Health, Diseases and Environment. Advances in Experimental Medicine and Biology, vol 996. Springer, Cham. https://doi.org/10.1007/978-3-319-56017-5_29

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