Radiation Therapy in Ependymal Tumors

Seidel, Clemens; Dietzsch, Stefan; Kortmann, Rolf-Dieter; Schackert, Gabriele; Hau, Peter

doi:10.1007/978-3-319-52619-5_4-1

Radiation Therapy in Ependymal Tumors

Clemens Seidel²,
Stefan Dietzsch²,
Rolf-Dieter Kortmann²,
Gabriele Schackert³ &
…
Peter Hau⁴

Living reference work entry
First Online: 29 February 2020

124 Accesses

Abstract

Ependymoma are rare malignant CNS tumors of the WHO grades I–III in children and adults with a tendency to spread within in the CSF. Several genetic subtypes with different clinical behaviors have been discovered. In localized tumors, gross total resection should be achieved. Radiotherapy is an effective adjuvant treatment and can also be used in in-operable cases. Efficacy of chemotherapy is very limited. Prognosis of metastatic and recurrent disease often remains poor.

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Authors and Affiliations

Department of Radiation Oncology, University Hospital Leipzig, Leipzig, Germany
Clemens Seidel, Stefan Dietzsch & Rolf-Dieter Kortmann
Department of Neurosurgery, University Hospital Carl Gustav Carus Dresden, Dresden, Germany
Gabriele Schackert
Wilhelm Sander NeuroOncology-Unit and Department of Neurology, University Hospital Regensburg, Regensburg, Germany
Peter Hau

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Clemens Seidel
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Stefan Dietzsch
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Rolf-Dieter Kortmann
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Gabriele Schackert
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Peter Hau
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Correspondence to Clemens Seidel .

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Department of Radiation Oncology, University Hospital Mannheim, Mannheim, Germany
Frederik Wenz

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Seidel, C., Dietzsch, S., Kortmann, RD., Schackert, G., Hau, P. (2020). Radiation Therapy in Ependymal Tumors. In: Wenz, F. (eds) Radiation Oncology. Springer, Cham. https://doi.org/10.1007/978-3-319-52619-5_4-1

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DOI: https://doi.org/10.1007/978-3-319-52619-5_4-1
Received: 03 February 2020
Accepted: 03 February 2020
Published: 29 February 2020
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-52619-5
Online ISBN: 978-3-319-52619-5
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