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Atlas of Dermatology, Dermatopathology and Venereology pp 1–80Cite as

The Genital, Perianal, and Umbilical Regions

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Abstract

Genitalia, perianal, and umbilical regions are commonly affected in various skin diseases. Some dermatoses are predominantly localized to these anatomic regions, and others may occur as a part of generalized cutaneous or systemic disease process. Apart from systemic investigations, a careful mucocutaneous examination and adequate knowledge of cutaneous disorders affecting such areas are essential to prevent the misdiagnosis and inappropriate treatment. A list encompassing all such important conditions has been prepared and discussed in brief. The sexually transmitted infections/diseases have been described in other chapters in this book.

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References

  • Abdel-Hamid IA, Anis T (2011) Peyronie’s disease: perspectives on therapeutic targets. Expert Opin Ther Targets 15(8):913–929

    Article  CAS  PubMed  Google Scholar 

  • Ackerman AB (1972) Focal acantholytic dyskeratosis. Arch Dermatol 106(5):702–706

    Article  CAS  PubMed  Google Scholar 

  • Adekunle AO, Fakokunde FA, Odukogbe AA, Fawole AO (1999) Female genital mutilation – postcircumcision vulval complications in Nigerians. J Obstet Gynaecol 19(6):632–635

    Article  CAS  PubMed  Google Scholar 

  • Adya KA, Palit A, Inamadar AC (2013) Pseudoepitheliomatous keratotic and micaceous balanitis. Indian J Sex Transm Dis 34(2):123–125

    Article  Google Scholar 

  • Afshan N, Gokhale L (2015) ‘Vulval oedema’: a conundrum! BMJ Case Rep 2015. pii: bcr2014206666

    Google Scholar 

  • Agarwal S, Berth-Jones J (2002) Porokeratosis of Mibelli: successful treatment with 5% imiquimod cream. Br J Dermatol 146(2):338–339

    Article  CAS  PubMed  Google Scholar 

  • Agarwal MM, Singh SK, Mandal AK (2007) Penile gangrene in diabetes mellitus with renal failure: a poor prognostic sign of systemic vascular calciphylaxis. Indian J Urol 23(2):208–210

    Article  PubMed  PubMed Central  Google Scholar 

  • Agrawal S, Kulshrestha R, Rijal A, Sidhu S (2004) Localized vulvar syringoma causing vulvar pruritus and venerophobia. Australas J Dermatol 45(4):236–237

    Article  PubMed  Google Scholar 

  • Ahmed AR, Blose DA (1984) Pemphigus vegetans. Neumann type and Hallopeau type. Int J Dermatol 23:135–141

    Article  CAS  PubMed  Google Scholar 

  • Ahmed U, Freeman A, Kirkham A, Ralph DJ, Minhas S, Muneer A (2017) Self injection of foreign materials into the penis. Ann R Coll Surg Engl 99(2):e78–e82

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Ahn C, Negus D, Huang W (2018) Pyoderma gangrenosum: a review of pathogenesis and treatment. Expert Rev Clin Immunol 14(3):225–233

    Article  CAS  PubMed  Google Scholar 

  • Akbulut F, Akbulut T, Kucukdurmaz F, Sonmezay E, Simsek A, Gurbuz G (2015) Huge pyogenic granuloma of the penis. Case Rep Urol 2015:263168

    PubMed  PubMed Central  Google Scholar 

  • Akhtar MA, Arora PK (2009) Case of unusual foreign body in the rectum. Saudi J Gastroenterol 15(2):131–132

    Article  PubMed  PubMed Central  Google Scholar 

  • Alcalde-Alonso M, Velasco-Albendea FJ, Soto-Diaz A, Gomez-Avivar P, Torres-Gomez FJ (2017) Paraffinoma of the penis and scrotum (sclerosing granuloma of the male genitalia). Indian J Dermatol Venereol Leprol 83:75–77

    Article  PubMed  Google Scholar 

  • Aldahan AS, Brah TK, Nouri K (2016) Diagnosis and management of pearly penile papules. Am J Mens Health 12(3):624–627

    Article  PubMed  PubMed Central  Google Scholar 

  • Al-Daraji WI, Wagner B, Ali RB, McDonagh AJ (2007) Sebaceous hyperplasia of the vulva: a clinicopathological case report with a review of the literature. J Clin Pathol 60(7):835–837

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Alidaee MR, Taheri A, Mansoori P, Ghodsi SZ (2005) Silver nitrate cautery in aphthous stomatitis: a randomized controlled trial. Br J Dermatol 153(3):521–525

    Article  CAS  PubMed  Google Scholar 

  • Allbritton JI (2017) Vulvar neoplasms, benign and malignant. Obstet Gynecol Clin N Am 44(3):339–352

    Article  Google Scholar 

  • Al-Ojaimi EH, Abdulla MM (2013) Giant epidermoid inclusion cyst of the clitoris mimicking clitoromegaly. J Low Genit Tract Dis 17(1):58–60

    Article  PubMed  Google Scholar 

  • Al-Shaiji TF, Amann J, Brock GB (2009) Fractured penis: diagnosis and management. J Sex Med 6(12):3231–3240

    Article  PubMed  Google Scholar 

  • Al-Thakafi S, Al-Hathal N (2016) Peyronie’s disease: a literature review on epidemiology, genetics, pathophysiology, diagnosis and work-up. Transl Androl Urol 5(3):280–289

    Article  PubMed  PubMed Central  Google Scholar 

  • Altstiel T, Coster R (1993) Bartholin cyst presenting as inguinal hernia. S D J Med 46(1):7–8

    CAS  PubMed  Google Scholar 

  • Amankwah Y, Haefner H (2010) Vulvar edema. Dermatol Clin 28(4):765–777

    Article  CAS  PubMed  Google Scholar 

  • Ameh EA, Mshelbwala PM, Dauda MM, Sabiu L, Nmadu PT (2005) Symptomatic vitelline duct anomalies in children. S Afr J Surg 43(3):84–85

    PubMed  Google Scholar 

  • Andreassi L, Bilenchi R (2014) Non-infectious inflammatory genital lesions. Clin Dermatol 32(2):307–314

    Article  PubMed  Google Scholar 

  • Aridogan IA, Izol V, Ilkit M (2011) Superficial fungal infections of the male genitalia: a review. Crit Rev Microbiol 37(3):237–244

    Article  PubMed  Google Scholar 

  • Arizaga AT, Gaughan MD, Bang RH (2002) Generalized lichen nitidus. Clin Exp Dermatol 27(2):115–117

    Article  CAS  PubMed  Google Scholar 

  • Asia AJ, Tapre VN (2016) Primary actinomycosis of vulva with inguinal lymphadenopathy. Indian Dermatol Online J 7(5):402–405

    Article  PubMed  PubMed Central  Google Scholar 

  • Bagrodia N, Defnet AM, Kandel JJ (2015) Management of lymphatic malformations in children. Curr Opin Pediatr 27(3):356–363

    Article  PubMed  Google Scholar 

  • Bandzar S, Gupta S, Platt MO (2013) Crohn’s disease: a review of treatment options and current research. Cell Immunol 286(1–2):45–52

    Article  CAS  PubMed  Google Scholar 

  • Banik R, Lubach D (1987) Skin tags: localization and frequencies according to sex and age. Dermatologica 174(4):180–183

    Article  CAS  PubMed  Google Scholar 

  • Banks E, Meirik O, Farley T, Akande O, Bathija H, Ali M (2006) Female genital mutilation and obstetric outcome: WHO collaborative prospective study in six African countries. WHO study group on female genital mutilation and obstetric outcome. Lancet 367(9525):1835–1841

    Article  PubMed  Google Scholar 

  • Bansal A, Kumar M, Goel S, Aeron R (2016) Vesicovaginal fistula following insertion of a foreign body in the vagina for sexual gratification: could it be catastrophic? BMJ Case Rep 2016. pii: bcr2016214705

    Google Scholar 

  • Barad P, Fernandes J, Shukla P (2014) Bowen’s disease: a favorable response to imiquimod. Indian Dermatol Online J 5(4):546–547

    Article  PubMed  PubMed Central  Google Scholar 

  • Baraziol R, Schiavon M, Fraccalanza E, De Giorgi G (2017) Melanoma in situ of penis: a very rare entity: a case report and review of the literature. Medicine (Baltimore) 96(36):e7652

    Article  Google Scholar 

  • Bardazzi F, Magnano M, Tengattini V, Loi C (2018) Pyoderma gangrenosum in the genital area: successful treatment using adalimumab. Eur J Dermatol 28(2):263–264

    PubMed  Google Scholar 

  • Barkat R, Das A, Kumar P, Savant SS (2017) Solitary plaque in the perianal region. Indian J Sex Transm Dis 38(1):96–97

    Article  Google Scholar 

  • Barlev D, Eisen DB, Alikhan A (2015) Hidradenitis suppurativa: a review with a focus on treatment data. Skin Therapy Lett 20(4):1–8

    CAS  PubMed  Google Scholar 

  • Barret M, de Parades V, Battistella M, Sokol H, Lemarchand N, Marteau P (2014) Crohn’s disease of the vulva. J Crohns Colitis 8(7):563–570

    Article  PubMed  Google Scholar 

  • Basta-Juzbašić A, Čeović R (2014) Chancroid, lymphogranuloma venereum, granuloma inguinale, genital herpes simplex infection, and molluscum contagiosum. Clin Dermatol 32(2):290–298

    Article  PubMed  Google Scholar 

  • Batta K, Munday PE, Tatnall FM (1999) Pemphigus vulgaris localized to the vagina presenting as chronic vaginal discharge. Br J Dermatol 140(5):945–947

    Article  CAS  PubMed  Google Scholar 

  • Bennet RG, Leyden JJ, Decherd JW (1973) The heroin ulcer. New addition to the differential diagnosis of ulcers of the penis. Arch Dermatol 107(1):121–122

    Article  Google Scholar 

  • Berg RC, Underland V, Odgaard-Jensen J, Fretheim A, Vist GE (2014) Effects of female genital cutting on physical health outcomes: a systematic review and meta-analysis. BMJ Open 4(11):e006316

    Article  PubMed  PubMed Central  Google Scholar 

  • Bhat RM, Furtado S (2007) Lipschutz ulcer. Indian J Sex Transm Dis 28(2):106–107

    Article  Google Scholar 

  • Bifulco G, Mandato VD, Piccoli R, Giampaolino P, Mignogna C, Mignogna MD, Costagliola L, Nappi C (2010) Early invasive vulvar squamous cell carcinoma arising in a woman with vulvar pemphigus vulgaris and systemic lupus erythematosus. BMC Cancer 10:324

    Article  PubMed  PubMed Central  Google Scholar 

  • Bilgiç Temel A, Bassorgun CI, Akman-Karakaş A, Alpsoy E, Uzun S (2017) Successful treatment of a bullous pemphigoid patient with rituximab who was refractory to corticosteroid and omalizumab treatments. Case Rep Dermatol 9(1):38–44

    Article  PubMed  PubMed Central  Google Scholar 

  • Bilgutay AN, Pastuszak AW (2016) Peyronie’s disease: what’s around the bend? Indian J Urol 32(1):6–14

    Article  PubMed  PubMed Central  Google Scholar 

  • Blankenship DW, Zech L, Mirzabeigi M, Venna S (2013) Verruciform xanthoma of the upper-extremity in the absence of chronic skin disease or syndrome: a case report and review of the literature. J Cutan Pathol 40(8):745–752

    Article  PubMed  Google Scholar 

  • Bonifaz A, Váquez-González D, Fierro L, Araiza J, Ponce RM (2013) Trichomycosis (trichobacteriosis): clinical and microbiological experience with 56 cases. Int J Trichology 5(1):12–16

    Article  PubMed  PubMed Central  Google Scholar 

  • Brady KL, Mercurio MG, Brown MD (2013) Malignant tumors of the penis. Dermatol Surg 39(4):527–547

    Article  CAS  PubMed  Google Scholar 

  • Brady M, Conway AB, Zaenglein AL, Helm KF (2016) Umbilical granuloma in a 2-month-old patient: histopathology of a common clinical entity. Am J Dermatopathol 38(2):133–134

    Article  PubMed  Google Scholar 

  • Brenn T (2011) Atypical genital nevus. Arch Pathol Lab Med 135(3):317–320

    PubMed  Google Scholar 

  • Bressan AL, Vasconcelos BN, Silva RS, Alves MFGS, Gripp AC (2010) Periumbilical and periareolar perforating pseudoxanthoma elasticum. An Bras Dermatol 85(5):705–707

    Article  PubMed  Google Scholar 

  • Brouwers MM, van der Zanden LF, de Gier RP, Barten EJ, Zielhuis GA, Feitz WF, Roeleveld N (2010) Hypospadias: risk factor patterns and different phenotypes. BJU Int 105(2):254–262

    Article  PubMed  Google Scholar 

  • Buechner SA (2002) Common skin disorders of the penis. BJU Int 90(5):498–506

    Article  CAS  PubMed  Google Scholar 

  • Bukvić Mokos Z, Kralj M, Basta-Juzbašić A, Lakoš Jukić I (2012) Seborrheic dermatitis: an update. Acta Dermatovenerol Croat 20(2):98–104

    PubMed  Google Scholar 

  • Bumb RA, Mehta RD (2006) Amoebiais cutis in HIV positive patient. Indian J Dermatol Venereol Leprol 72(3):224–226

    Article  CAS  PubMed  Google Scholar 

  • Bunker CB, Shim TN (2015) Male genital lichen sclerosus. Indian J Dermatol 60(2):111–117

    Article  PubMed  PubMed Central  Google Scholar 

  • Burrows NP, Sonnex C, Roberts SO, Carne CA (1993) Cutaneous vasculitis presenting on the penis. Genitourin Med 69(4):301–302

    CAS  PubMed  PubMed Central  Google Scholar 

  • Byer TT, Morrell DS (2004) Periumbilical allergic contact dermatitis: blue jeans or belt buckles? Pediatr Dermatol 21(3):223–226

    Article  PubMed  Google Scholar 

  • Campagne G, Roca M, Martínez A (2003) Successful treatment of a high-grade intraepithelial neoplasia with imiquimod, with vulvar pemphigus as a side effect. Eur J Obstet Gynecol Reprod Biol 109(2):224–227

    Article  CAS  PubMed  Google Scholar 

  • Campaner AB, Fernandes GL, Cardoso FA, Veasey JV (2017a) Vulvar melanoma: relevant aspects in therapeutic management. An Bras Dermatol 92(3):398–400

    Article  PubMed  PubMed Central  Google Scholar 

  • Campaner AB, Cardoso FA, Fernandes GL, Veasey JV (2017b) Verrucous carcinoma of the vulva: diagnosis and treatment. An Bras Dermatol 92(2):243–245

    Article  PubMed  PubMed Central  Google Scholar 

  • Campbell J, Beasley SW, McMullin N, Hutson JM (1986) Clinical diagnosis of umbilical swellings and discharges in children. Med J Aust 145(9):450–453

    Article  CAS  PubMed  Google Scholar 

  • Canalizo-Almeida S, Mercadillo-Pérez P, Tirado-Sánchez A (2007) Giant skin tags: report of two cases. Dermatol Online J 13(3):30

    PubMed  Google Scholar 

  • Chamberlain JM, Gorman RL, Young GM (1992) Silver nitrate burns following treatment for umbilical granuloma. Pediatr Emerg Care 8(1):29–30

    Article  CAS  PubMed  Google Scholar 

  • Chandail VS, Jamwal V (2013) Caput medusae. J Assoc Physicians India 61(8):564

    PubMed  Google Scholar 

  • Chandawarkar RY, Ricchuiti D, Amjad I, Marsico RE Jr, Wells MK (2003) Extramammary Paget’s disease of the perineum: avoiding pitfalls in diagnosis and management. Can J Plast Surg 11(4):205–208

    Article  PubMed  PubMed Central  Google Scholar 

  • Chang J, McLemore E, Tejirian T (2016) Anal health care basics. Perm J 20(4):74–80

    Google Scholar 

  • Chaudhary K, Smith RJ, Himelright IM, Baddour LM (1994) Case report: purpura in disseminated strongyloidiasis. Am J Med Sci 308(3):186–191

    Article  CAS  PubMed  Google Scholar 

  • Chen TJ, Chow YC, Chen CH, Kuo TT, Hong HS (2006) Genital porokeratosis: a series of 10 patients and review of the literature. Br J Dermatol 155(2):325–329

    Article  PubMed  Google Scholar 

  • Chennamsetty A, Khourdaji I, Burks F, Killinger KA (2015) Contemporary diagnosis and management of Fournier’s gangrene. Ther Adv Urol 7(4):203–215

    Article  PubMed  PubMed Central  Google Scholar 

  • Chintapatla S, Safarani N, Kumar S, Haboubi N (2003) Sacrococcygeal pilonidal sinus: historical review, pathological insight and surgical options. Tech Coloproctol 7(1):3–8

    Article  CAS  PubMed  Google Scholar 

  • Chorzelski TP, Kudejko J, Jablonska S (1984) Is papular acantholytic dyskeratosis of the vulva a new entity? Am J Dermatopathol 6(6):557–560

    Article  CAS  PubMed  Google Scholar 

  • Choudhary S, Koley S, Salodkar A (2010) A modified surgical technique for Steatocystoa multiplex. J Cutan Aesthet Surg 3(1):25–28

    Article  PubMed  PubMed Central  Google Scholar 

  • Chowdappa V, Narasimha A, Bhat A, Masamatti SS (2015) Solitary angiokeratoma: report of two uncommon cases. J Clin Diagn Res 9(5):WD01–WD02

    PubMed  PubMed Central  Google Scholar 

  • Chuanyu S, Ke X, Jie Z, Guowei X, Zujun F, Qiang D (2011) Surgical treatment for 11 cases of penile verrucous carcinoma. Ann Dermatol 23(Suppl 3):S346–S349

    Article  PubMed  PubMed Central  Google Scholar 

  • Chung WH, Wang CW, Dao RL (2016) Severe cutaneous adverse drug reactions. J Dermatol 43(7):7 58–766

    Article  CAS  PubMed  Google Scholar 

  • Ciampo IRLD, Sawamura R, Ciampo LAD, Fernandes MIM (2018) Acrodermatitis entropathica: clinical manifestations and pediatric diagnosis. Rev Paul Pediatr 36(2):238–241

    Article  PubMed  PubMed Central  Google Scholar 

  • Cinotti E, Tonini G, Perrot JL, Habougit C, Luisi S, Rubegni P (2018) Dermoscopic and reflectance confocal microscopy features of two cases of vulvar basal cell carcinoma. Dermatol Pract Concept 8(1):68–71

    Article  PubMed  PubMed Central  Google Scholar 

  • Clemente N, Alessandrini L, Rupolo M, Bulian P, Lucia E, Canzonieri V, Sopracordevole F (2016) Primary non-Hodgkin’s lymphoma of the vulva: a case report and literature review. Medicine (Baltimore) 95(10):e3041

    Article  Google Scholar 

  • Cohen PR, Tschen JA, Rapini RP (2013) Penile syringoma: reports and review of patients with syringoma located on the penis. J Clin Aesthet Dermatol 6(6):38–42

    PubMed  PubMed Central  Google Scholar 

  • Cole LA, Helwig EB (1976) Mucoid cyst of penile skin. J Urol 115(4):397–400

    Article  CAS  PubMed  Google Scholar 

  • Cooper SM, Haefner HK, Abrahams-Gessel S, Margesson LJ (2008) Vulvovaginal lichen planus treatment: a survey of current practices. Arch Dermatol 144(11):1520–1521

    PubMed  Google Scholar 

  • Coughlin CC, Eichenfield LF, Frieden IJ (2014) Diaper dermatitis: clinical characteristics and differential diagnosis. Pediatr Dermatol 31(Suppl 1):19–24

    Article  PubMed  Google Scholar 

  • Cox GA, Chan I, Lloyd J, Witherow RO, Leonard JN (2007) Urachal sinus presenting as periumbilical dermatitis. Br J Dermatol 157(2):419–420

    Article  CAS  PubMed  Google Scholar 

  • Cozzani E, Gasparini G, Parodi A (2014) Pyoderma gangrenosum: a systematic review. G Ital Dermatol Venereol 149(5):587–600

    CAS  PubMed  Google Scholar 

  • Cozzani E, Rongioletti F, Ciccarese G, Drago F, Parodi A (2016) Necrobiotic granuloma annulare of the penis: a case responding to anti-tuberculosis therapy with a review of the literature. J Eur Acad Dermatol Venereol 30(1):198–200

    Article  CAS  PubMed  Google Scholar 

  • Cribier B, Scrivener Y, Grosshans E (2001) Molluscum contagiosum: histologic patterns and associated lesions. A study of 578 cases. Am J Dermatopathol 23(2):99–103

    Article  CAS  PubMed  Google Scholar 

  • Czuczwar P, Stępniak A, Goren A, Wrona W, Paszkowski T, Pawlaczyk M, Piekarska-Myślińska D, Woźniak S, Pietrzak A (2016) Genital psoriasis: a hidden multidisciplinary problem – a review of literature. Ginekol Pol 87(10):717–721

    Article  PubMed  Google Scholar 

  • Dandapat MC, Mohapatro SK, Patro SK (1985) Elephantiasis of the penis and scrotum. A review of 350 cases. Am J Surg 149(5):686–690

    Article  CAS  PubMed  Google Scholar 

  • Daniel F, Mahmoudi A, de Parades V, Flejou JF, Atienza P (2007) An uncommon perianal nodule: Hidradenoma papilliferum. Gastroenterol Clin Biol 31(2):166–168

    Article  PubMed  Google Scholar 

  • Dare AJ, Axelsen RA (1988) Scrotal calcinosis: origin from dystrophic calcification of eccrine duct milia. J Cutan Pathol 15(3):142–149

    Article  CAS  PubMed  Google Scholar 

  • Das A, Mondal AK, Saha A, Chowdhury SN, Gharami RC (2014) Angiokeratoma circumscriptum neviforme: an entity, few and far between. Indian Dermatol Online J 5(4):472–474

    Article  PubMed  PubMed Central  Google Scholar 

  • Dayal S, Sahu P (2016) Zoon balanitis: a comprehensive review. Indian J Sex Transm Dis 37(2):129–138

    Article  Google Scholar 

  • De Mendonça RR, Silva Ii JL, Wroclawski ML, Sakuramoto PK, Pompeo AC (2010) Mucoid cyst of the penis: case report and literature review. Can Urol Assoc J 4(6):E155–E157

    Article  PubMed  PubMed Central  Google Scholar 

  • de Moll EH, Lambert WC, Parish LC (2014) Steatocystoma multiplex: those little tumours. Skinmed 12(5):267–269

    PubMed  Google Scholar 

  • De Siati M, Selvaggio O, Di Fino G, Liuzzi G, Massenio P, Sanguedolce F, Carrieri G, Cormio L (2013) An unusual delayed complication of paraffin self-injection for penile girth augmentation. BMC Urol 13:66

    Article  PubMed  PubMed Central  Google Scholar 

  • Deger A, Yaylak F, Bayhan Z (2014) Endometriosis in the surgical scar tissue after caesarean section. Ann Clin Pathol 2(2):1022

    Google Scholar 

  • Demir S, Demir Y (2002) Acrochordon and impaired carbohydrate metabolism. Acta Diabetol 39(2):57–59

    Article  CAS  PubMed  Google Scholar 

  • Derakhshan MR (1998) Curative effect of common salt on umbilical granuloma. Iran J Med Sci 23:132–133

    Google Scholar 

  • Dessinioti C, Katsambas A (2013) Seborrheic dermatitis: etiology, risk factors, and treatments: facts and controversies. Clin Dermatol 31(4):343–351

    Article  PubMed  Google Scholar 

  • Deveza E, Locatelli F, Girardin M, Valmary-Degano S, Daguindau E, Aubin F, Humbert P, Pelletier F (2015) Vulvar oedema revealing systemic mastocytosis. Ann Dermatol Venereol 142(11):685–689

    Article  CAS  PubMed  Google Scholar 

  • Diaz Gonzales JM, Martinez Luna E, Pena Romero A, Molina Hernandez A, Dominguez Cherit J (2013) Vestibular papillomatosis as a normal vulvar anatomical condition. Dermatol Online J 19(10):20032

    PubMed  Google Scholar 

  • DiSantis DJ, Siegel MJ, Katz ME (1991) Simplified approach to umbilical remnant abnormalities. Radiographics 11(1):59–66

    Article  CAS  PubMed  Google Scholar 

  • Divakaruni AK, Rao AV, Mahabir B (2008) Erythroplasia of Queyrat with Zoon’s balanitis: a diagnostic dilemma. Int JSTD AIDS 19(12):861–863

    Article  CAS  Google Scholar 

  • Do-Pham G, Monsel G, Chosidow O (2014) Lice. Semin Cutan Med Surg 33(3):116–118

    Article  PubMed  Google Scholar 

  • Douglas-Jones AG, Rodd C, James EM, Mills RG (1992) Prediagnostic malakoplakia presenting as a chronic inflammatory mass in the soft tissues of the neck. J Laryngol Otol 106(2):173–177

    Article  CAS  PubMed  Google Scholar 

  • Dubey S, Sharma R, Maheshwari V (2010) Scrotal calcinosis: idiopathic or dystrophic? Dermatol Online J 16(2):5

    PubMed  Google Scholar 

  • Dubreuil A, Dompmartin A, Barjot P, Louvet S, Leroy D (1998) Umbilical metastasis or Sister Mary Joseph’s nodule. Int J Dermatol 37(1):7–13

    Article  CAS  PubMed  Google Scholar 

  • Edwards S (1996) Balanitis and balanoposthitis: a review. Genitourin Med 72(3):155–159

    CAS  PubMed  PubMed Central  Google Scholar 

  • Eisen D (1994) The vulvovaginal-gingival syndrome of lichen planus. The clinical characteristics of 22 patients. Arch Dermatol 130(11):1379–1382

    Article  CAS  PubMed  Google Scholar 

  • Ekwueme KC, Parr NJ (2009) Infected urachal cyst in an adult: a case report and review of the literature. Cases J 2:6422

    Article  PubMed  PubMed Central  Google Scholar 

  • El Ammari JE, Ahallal Y, El Yazami AO, El Fassi MJ, Farih MH (2011) Urachal sinus presenting with abscess formation. ISRN Urol 2011:820924

    PubMed  PubMed Central  Google Scholar 

  • Farrell AM, Kirtschig G, Dalziel KL, Allen J, Dootson G, Edwards S, Wojnarowska F (1999) Childhood vulval pemphigoid: a clinical and immunopathological study of five patients. Br J Dermatol 140(2):308–312

    Article  CAS  PubMed  Google Scholar 

  • Feldmeyer L, Krausz-Enderlin V, Töndury B, Hafner J, French LE, Hofbauer GF (2011) Methylaminolaevulinic acid photodynamic therapy in the treatment of erythroplasia of Queyrat. Dermatology 223(1):52–56

    Article  CAS  PubMed  Google Scholar 

  • Feng H, Kim RH, Brinster N, Ho R, Pomeranz MK (2016) Scrotal lymphangioma circumscriptum. Dermatol Online J 22(12). pii: 13030/qt0068f0nc

    Google Scholar 

  • Fischer G (2007) Vulvar fixed drug eruption. A report of 13 cases. J Reprod Med 52(2):81–86

    PubMed  Google Scholar 

  • Flowers H, Brodell R, Brents M, Wyatt JP (2014) Fixed drug eruptions: presentation, diagnosis, and management. South Med J 107(11):724–727

    Article  PubMed  Google Scholar 

  • Font RL, Bersani TA, Eagle RC Jr (1988) Malakoplakia of the eyelid: clinical, histopathologic, and ultrastructural characteristics. Ophthalmology 95(1):61–68

    Article  CAS  PubMed  Google Scholar 

  • Fornasa CV, Calabro A, Miglietta A, Tarantello M, Biasinutto C, Peserico A (1994) Mild balanoposthitis. Genitourin Med 70(5):345–346

    CAS  PubMed  PubMed Central  Google Scholar 

  • Foxton G, Vinciullo C, Tait CP, Sinniah R (2011) Sclerosing lipogranuloma of the penis. Australas J Dermatol 52(2):e12–e14

    Article  PubMed  Google Scholar 

  • Fueston JC, Adams BB, Mutasim DF (2002) Cicatricial pemphigoid-induced phimosis. J Am Acad Dermatol 46(5 Suppl):S128–S129

    Article  PubMed  Google Scholar 

  • Funaro D (2004) Lichen sclerosus: a review and practical approach. Dermatol Ther 17:28–37

    Article  PubMed  Google Scholar 

  • Galvañ VG (1998) Sister Mary Joseph’s nodule. Ann Intern Med 128(5):410

    Article  PubMed  Google Scholar 

  • Gangkak G, Mishra A, Priyadarshi S, Tomar V (2015) Large genital cavernous hemangioma: a rare surgically correctable entity. Case Rep Urol 2015:950819

    PubMed  PubMed Central  Google Scholar 

  • Garg T, Mittal S (2012) Vesicobullous disorders of female genitalia. Indian J Sex Transm Dis 33(1):1–8

    Article  Google Scholar 

  • Gattu S, Rashid RM, Khachemoune A (2009) Self-induced skin lesions: a review of dermatitis artefacta. Cutis 84(5):247–251

    PubMed  Google Scholar 

  • Gennis P, Li SF, Provataris J, Shahabuddin S, Schachtel A, Lee E, Bobby P (2005) Jacobi ring catheter treatment of Bartholin’s abscesses. Am J Emerg Med 23(3):414–415

    Article  PubMed  Google Scholar 

  • George A, Mani V, Noufal A (2014) Update on the classification of hemangioma. J Oral Maxillofac Pathol 18(Suppl 1):S117–S120

    Article  PubMed  PubMed Central  Google Scholar 

  • Giblin AV, Clover AJ, Athanassopoulos A, Budny PG (2007) Pyogenic granuloma-the quest for optimum treatment: audit of treatment of 408 cases. J Plast Reconstr Aesthet Surg 60(9):1030–1035

    Article  CAS  PubMed  Google Scholar 

  • Gibson GE, Ahmed I (2001) Perianal and genital basal cell carcinoma: a clinicopathologic review of 51 cases. J Am Acad Dermatol 45(1):68–71

    Article  CAS  PubMed  Google Scholar 

  • Glazer G (1973) Primary adenocarcinoma arising in a vitellointestinal duct remnant at the umbilicus. Br J Surg 60(3):247–249

    Article  CAS  PubMed  Google Scholar 

  • Goeser MR, Laniosz V, Wetter DA (2014) A practical approach to the diagnosis, evaluation, and management of cutaneous small-vessel vasculitis. Am J Clin Dermatol 15(4):299–306

    Article  PubMed  Google Scholar 

  • Gokhale BB, Mehta LN (1983) Histopathology of vitiliginous skin. Int J Dermatol 22(8):477–480

    Article  CAS  PubMed  Google Scholar 

  • Golant AK, Levitt JO (2012) Scabies: a review of diagnosis and management based on mite biology. Pediatr Rev 33(1):e1–e12

    Article  PubMed  Google Scholar 

  • Gong Z, Zhang Y, Chu H, Lian P, Zhang L, Sun P, Chen J (2014) Priapism as the initial symptom of primary penile lymphoma: a case report. Oncol Lett 8(5):1929–1932

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Goyal M, Kriplani A, Mahey R, Kachhawa G, Yadav R, Singh G (2017) Giant congenital melanocytic nevus presenting as a huge vulvar mass: a rare case. Taiwan J Obstet Gynecol 56(1):109–111

    Article  PubMed  Google Scholar 

  • Greenberger S, Bischoff J (2013) Pathogenesis of infantile haemangioma. Br J Dermatol 169(1):12–19

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Grosshans E, Laplanche G (1981) Verruciform xanthoma or xanthomatous transformation of inflammatory epidermal nevus? J Cutan Pathol 8(5):382–384

    Article  CAS  PubMed  Google Scholar 

  • Gültekin IB, Altınboğa O, Rıza D, Kara OF, Küçüközkan T (2016) Surgical reconstruction in female genital mutilation. Turk J Urol 42(2):111–114

    Article  PubMed  PubMed Central  Google Scholar 

  • Gunning K, Pippitt K, Kiraly B, Sayler M (2012) Pediculosis and scabies: treatment update. Am Fam Physician 86(6):535–541

    PubMed  Google Scholar 

  • Gupta AK, Bluhm R (2004) Seborrheic dermatitis. J Eur Acad Dermatol Venereol 18(1):13–26

    Article  CAS  PubMed  Google Scholar 

  • Gupta LK, Martin AM, Agarwal N, D’Souza P, Das S, Kumar R, Pande S, Das NK, Kumaresan M, Kumar P, Garg A, Singh S (2016) Guidelines for the management of Stevens–Johnson syndrome/toxic epidermal necrolysis: an Indian perspective. Indian J Dermatol Venereol Leprol 82(6):603–625

    Article  PubMed  Google Scholar 

  • Güvenç H, Aygün AD, Yaşar F, Soylu F, Güvenç M, Kocabay K (1997) Omphalitis in term and preterm appropriate for gestational age and small for gestational age infants. J Trop Pediatr 43:368–372

    Article  PubMed  Google Scholar 

  • Hagedorn JC, Wessells H (2017) A contemporary update on Fournier’s gangrene. Nat Rev Urol 14(4):205–214

    Article  CAS  PubMed  Google Scholar 

  • Haley JC, Mirowski GW, Hood AF (1998) Benign vulvar tumors. Semin Cutan Med Surg 17(3):196–204

    Article  CAS  PubMed  Google Scholar 

  • Hall DE, Roberts KB, Charney E (1981) Umbilical hernia: what happens after age 5 years? J Pediatr 98(3):415–417

    Article  CAS  PubMed  Google Scholar 

  • Hardy KM, Perry HO, Pingree GC, Kirby TJ Jr (1971) Benign mucous membrane pemphigoid. Arch Dermatol 104(5):467–475

    Article  CAS  PubMed  Google Scholar 

  • Harr T, French LE (2010) Toxic epidermal necrolysis and Stevens-Johnson syndrome. Orphanet J Rare Dis 5:39

    Article  PubMed  PubMed Central  Google Scholar 

  • Hay RJ, Steer AC, Engelman D, Walton S (2012) Scabies in the developing world – its prevalence, complications, and management. Clin Microbiol Infect 18(4):313–323

    Article  CAS  PubMed  Google Scholar 

  • Hayashi Y, Kojima Y, Mizuno K, Kohri K (2011) Prepuce: phimosis, paraphimosis, and circumcision. Sci World J 11:289–301

    Article  Google Scholar 

  • Haycox CL, Kuypers J, Krieger JN (1999) Role of human papillomavirus typing in diagnosis and clinical decision making for giant verrucouslesion. Urology 53(3):627–630

    Article  CAS  PubMed  Google Scholar 

  • Heller MM, Wong JW, Lee ES, Ladizinski B, Grau M, Howard JL, Berger TG, Koo JY, Murase JE (2013) Delusional infestations: clinical presentation, diagnosis and treatment. Int J Dermatol 52(7):775–783

    Article  PubMed  Google Scholar 

  • Hernandez-Gil J, Guiote MV, Vilanova A, Mendoza F, Linares J, Naranjo R (2006) Genital artefact ulcers appearing simultaneously in a couple. Actas Dermosifiliogr 97(2):122–125

    Article  PubMed  Google Scholar 

  • Hicheri J, Badri T, Fazaa B, Zermani R, Kourda N, Jilani SB, Kamoun MR (2005) Scrotal calcinosis: pathogenesis and case report. Acta Dermatovenerol Alp Panonica Adriat 14(2):53–56

    Google Scholar 

  • Hicks MI, Elston DM (2009) Scabies. Dermatol Ther 22(4):279–292

    Article  PubMed  Google Scholar 

  • Higgins SP, Freemark M, Prose NS (2008) Acanthosis nigricans: a practical approach to evaluation and management. Dermatol Online J 14(9):2

    PubMed  Google Scholar 

  • Horn AS, Pecora A, Chiesa JC, Alloy A (1985) Penile thrombophlebitis as a persistent manifestation of pancreatic carcinoma. Am J Gastroenterol 80(6):463–465

    CAS  PubMed  Google Scholar 

  • Hoşcan MB, Akkaya H, Tunçkıran A, Durusoy C (2012) Massive idiopathic scrotal calcinosis. Urology 80(6):e71–e72

    Article  PubMed  Google Scholar 

  • Hoshi A, Usui Y, Terachi T (2008) Penile carcinoma originating from lichen planus on glans penis. Urology 71(5):816–817

    Article  PubMed  Google Scholar 

  • Hsieh WS, Yang PH, Chao HC, Lai JY (1999) Neonatal necrotizing fasciitis: a report of three cases and review of the literature. Pediatrics 103(4):e53

    Article  CAS  PubMed  Google Scholar 

  • Huang YH, Chuang YH, Kuo TT, Yang LC, Hong HS (2003) Vulvar syringoma: a clinicopathologic and immunohistologic study of 18 patients and results of treatment. J Am Acad Dermatol 48(5):735–739

    Article  PubMed  Google Scholar 

  • Huff JC (1985) Erythema multiforme. Dermatol Clin 3(1):141–152

    Article  CAS  PubMed  Google Scholar 

  • Hugh JM, Lesiak K, Greene LA, Pierson JC (2014) Zoon’s balanitis. J Drugs Dermatol 13(10):1290–1291

    PubMed  Google Scholar 

  • Huilaja L, Mäkikallio K, Tasanen K (2014) Gestational pemphigoid. Orphanet J Rare Dis 9:136

    Article  PubMed  PubMed Central  Google Scholar 

  • Isbary G, Dyall-Smith D, Coras-Stepanek B, Stolz W (2014) Penile lentigo (genital mucosal macule) following annular lichen planus: a possible association? Australas J Dermatol 55(2):159–161

    Article  PubMed  Google Scholar 

  • Ito A, Sakamoto F, Ito M (2001) Dystrophic scrotal calcinosis originating from benign eccrine epithelial cysts. Br J Dermatol 144(1):146–150

    Article  CAS  PubMed  Google Scholar 

  • Jabiles AG, Del Mar EY, Perez GAD, Vera FQ, Montoya LM, Deza CMM (2017) Penile melanoma: a 20-year analysis of six patients at the National Cancer Institute of Peru, Lima. Ecancermedicalscience 11:731

    PubMed  PubMed Central  Google Scholar 

  • Jemec GB, Kimball AB (2015) Hidradenitis suppurativa: epidemiology and scope of the problem. J Am Acad Dermatol 73(5 Suppl 1):S4–S7

    Article  PubMed  Google Scholar 

  • Jones DJ (1992) ABC of colorectal diseases. Pruritus ani. BMJ 305(6853):575–577

    Article  CAS  PubMed  Google Scholar 

  • Josey WE (1988) Anovaginal fistula presenting as a vulvar ulcer: a report of two cases in postmenopausal women. J Reprod Med 33(10):857–858

    CAS  PubMed  Google Scholar 

  • Jung JH, Kwak C, Kim HH, Ku JH (2013) Extramammary Paget disease of external genitalia: surgical excision and follow-up experiences with 19 patients. Korean J Urol 54(12):834–839

    Article  PubMed  PubMed Central  Google Scholar 

  • Kakkar S, Sharma PK (2017) Benign vulvar vestibular papillomatosis: an underreported condition in Indian dermatological literature. Indian Dermatol Online J 8(1):63–65

    Article  PubMed  PubMed Central  Google Scholar 

  • Kalb RE, Grossman ME (1986) Periumbilical purpura in disseminated strongyloidiasis. JAMA 256(9):1170–1171

    Article  CAS  PubMed  Google Scholar 

  • Kamra HT, Gadgil PA, Ovhal AG, Narkhede RR (2013) Steatocystoma multiplex-a rare genetic disorder: a case report and review of the literature. J Clin Diagn Res 7(1):166–168

    PubMed  PubMed Central  Google Scholar 

  • Kang HG, Park MC, Park DH (2014) A new modality for treating congenital melanocytic nevus: “cogwheel pattern” serial excision method. Arch Plast Surg 41(4):418–420

    Article  PubMed  PubMed Central  Google Scholar 

  • Kaporis A, Lynfield Y (1988) Penile lentiginosis. J Am Acad Dermatol 38:781

    Article  Google Scholar 

  • Karki K, Mohsin R, Mubarak M, Hashmi A (2013) Primary non-Hodgkin’s lymphoma of penis masquerading as a non-healing ulcer in the penile shaft. Nephrourol Mon 5(3):840–842

    Article  PubMed  PubMed Central  Google Scholar 

  • Kasana S, Din J, Maret W (2015) Genetic causes and gene–nutrient interactions in mammalian zinc deficiencies: acrodermatitis enteropathica and transient neonatal zinc deficiency as examples. J Trace Elem Med Biol 29:47–62

    Article  CAS  PubMed  Google Scholar 

  • Kaur T, Dhawan S, Aggarwal A, Bansal S (2012) Vulval tuberculosis. J Obstet Gynaecol India 62(4):450–451

    Article  PubMed  PubMed Central  Google Scholar 

  • Keen MA, Hassan I (2014) Eruptive angiokeratomas on the glans penis. Indian J Dermatol 59(4):424

    Article  PubMed  PubMed Central  Google Scholar 

  • Keimig EL (2015) Granuloma annulare. Dermatol Clin 33(3):315–329

    Article  CAS  PubMed  Google Scholar 

  • Keogan MT (2009) Clinical immunology review series: an approach to the patient with recurrent orogenital ulceration including Behçet’s syndrome. Clin Exp Immunol 156(1):1–11

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Khachemoune A, Guldbakke KK, Ehrsam E (2006) Infantile perineal protrusion. J Am Acad Dermatol 54(6):1046–1049

    Article  PubMed  Google Scholar 

  • Kharfi M, Khaled A, Karaa A, Zaraa I, Fazaa B, Kamoun MR (2010) Linear IgA bullous dermatosis: the more frequent bullous dermatosis of children. Dermatol Online J 16(1):2

    PubMed  Google Scholar 

  • Kieliszak CR, Pollinger TH, Tollefson MM, Griffin JR (2015) Umbilical and periumbilical dermatoses. J Am Acad Dermatol 72(6):1066–1073

    Article  PubMed  Google Scholar 

  • Kim MY, Lee JS, Kim HO, Park YM (2004) A case of nevoid acanthosis nigricans. Acta Derm Venereol 84(3):234–235

    Article  PubMed  Google Scholar 

  • Kim SH, Seo SH, Ko HC, K won KS, Kim MB (2009) The use of dermoscopy to differentiate vestibular papillae, a normal variant of the female external genitalia, from condyloma acuminata. J Am Acad Deratol 60(2): 353–355

    Article  PubMed  Google Scholar 

  • Kim HS, Lee JY, Kim HO, Park YM (2011) Sebaceous hyperplasia of the scrotum and penile shaft. Ann Dermatol 23(Suppl 3):S341–S342

    Article  PubMed  PubMed Central  Google Scholar 

  • Kirshen C, Edwards L (2015) Noninfectious genital ulcers. Semin Cutan Med Surg 34(4):187–191

    Article  PubMed  Google Scholar 

  • Kirtschig G (2016) Lichen sclerosus-presentation, diagnosis and management. Dtsch Arztebl Int 113(19):337–343

    PubMed  PubMed Central  Google Scholar 

  • Kirtschig G, Murrell D, Wojnarowska F, Khumalo N (2002) Interventions for mucous membrane pemphigoid/cicatricial pemphigoid and epidermolysis bullosa acquisita: a systematic literature review. Arch Dermatol 138(3):380–384

    Article  PubMed  Google Scholar 

  • Klunk C, Domingues E, Wiss K (2014) An update on diaper dermatitis. Clin Dermatol 32(4):477–487

    Article  PubMed  Google Scholar 

  • Knight SR, Proby CP, Ziyaie D, Carey F, Koch S (2016) Extramammary Paget disease of the perianal region: the potential role of imiquimod in achieving disease control. J Surg Case Rep 2016(8):rjw110

    Article  PubMed  PubMed Central  Google Scholar 

  • Ko CJ, Elston DM (2004) Pediculosis. J Am Acad Dermatol 50(1):1–12

    Article  PubMed  Google Scholar 

  • Koblenzer CS (2000) Dermatitis artefacta. Clinical features and approaches to treatment. Am J Clin Dermatol 1(1):47–55

    Article  CAS  PubMed  Google Scholar 

  • Koc O, Sengul N, Gurel S (2010) Perineal leiomyoma mimicking complex Bartholin mass. Int Urogynecol J 21(4):495–497

    Article  PubMed  Google Scholar 

  • Kocatürk E, Kavala M, Zindanci I, Koç M (2009) Periumbilical perforating pseudoxanthoma elasticum. Indian J Dermatol Venereol Leprol 75(3):329

    Article  PubMed  Google Scholar 

  • Kohl SK, Hans CP (2008) Cutaneous malakoplakia. Arch Pathol Lab Med 132(1):113–117

    PubMed  Google Scholar 

  • Koifman L, Barros R, Júnior RA, Cavalcanti AG, Favorito LA (2010) Penile fracture: diagnosis, treatment and outcomes of 150 patients. Urology 76(6):1488–1492

    Article  PubMed  Google Scholar 

  • Kothiwala SK, Khandpur S, Singh MK, Durgapal P (2015) Erythema nodosum leprosum on glans penis: unusual manifestation of common disease. Int J Dermatol 54(9):1060–1063

    Article  PubMed  Google Scholar 

  • Kraft KH, Shukla AR, Canning DA (2010) Hypospadias. Urol Clin North Am 37(2):167–181

    Article  PubMed  Google Scholar 

  • Krishnan RS, Ledbetter LS, Reed JA, Hsu S (2001) Acantholytic dermatosis of the vulvocrural area. Cutis 67(3):217–220

    CAS  PubMed  Google Scholar 

  • Krishnaram AS (1991) Unilateral nevoid acanthosis nigricans. Int J Dermatol 30(6):452–453

    Article  CAS  PubMed  Google Scholar 

  • Kudur MH, Hulmani M (2013) Giant angiokeratoma of Fordyce over the vulva in a middle-aged woman: case report and review of literature. Indian J Dermatol 58(3):242

    Article  PubMed  PubMed Central  Google Scholar 

  • Kumar P, Kanti Das N (2016) Cyclosporine in toxic epidermal necrolysis: a brief review of the emerging therapeutic modality. Dermatol Online J 22(10). pii: 13030/qt3m82s074

    Google Scholar 

  • Kumar B, Kaur I, Rai R, Mandal SK, Sharma VK (2001) Involvement of male genitalia in leprosy. Lepr Rev 72(1):70–77

    CAS  PubMed  Google Scholar 

  • Kumar P, Lal NR, Mondal AK, Mondal A, Gharami RC, Maiti A (2012) Zinc and skin: a brief summary. Dermatol Online J 18(3):1

    PubMed  Google Scholar 

  • Kumar S, Mahajan BB, Ahluwalia RS, Boparai AS (2015) Reiter’s disease: circinate balanitis as alone preceding presentation – successfully treated with pimecrolimus 1% cream. Indian J Sex Transm Dis 36(1):70–73

    Article  CAS  Google Scholar 

  • Kumar P, Savant SS, Barkat R (2016) Periumbilical perforating pseudoxanthoma elasticum. Dermatol Online J 22(11). pii: 13030/qt2hp829fz

    Google Scholar 

  • Kumar P, Das A, Savant SS, Barkat R (2017) Median raphe cyst: report of two cases. Dermatol Online J 23(2). pii: 13030/qt2fx2x9b0

    Google Scholar 

  • Kutlubay Z, Engin B, Bairamov O, Tüzün Y (2015) Acanthosis nigricans: a fold (intertriginous) dermatosis. Clin Dermatol 33(4):466–470

    Article  PubMed  Google Scholar 

  • Lakdawala N, Grant-Kels JM (2015) Acrodermatitis enteropathica and other nutritional diseases of the folds (intertriginous areas). Clin Dermatol 33(4):414–419

    Article  PubMed  Google Scholar 

  • Lamberti A, Filippou G, Adinolfi A, Fimiani M, Rubegni P (2015) Infantile perianal pyramidal protrusion: a case report with dermoscopy and ultrasound findings. Dermatol Pract Concept 5(2):125–128

    PubMed  PubMed Central  Google Scholar 

  • Larentzakis A, Theodorou D, Fili K, Manataki A, Bizimi V, Tibishrani M, Katsaragakis S (2008) Sister Mary Joseph’s nodule: three case reports. Cases J 1:182

    Article  PubMed  PubMed Central  Google Scholar 

  • Larsson KB, Shaw HM, Thompson JF, Harman RC, McCarthy WH (1999) Primary mucosal and glans penis melanomas: the Sydney Melanoma Unit experience. Aust N Z J Surg 69(2):121–126

    Article  CAS  PubMed  Google Scholar 

  • Lashgari M, Keene M (1986) Excision of Bartholin duct cysts using the CO2 laser. Obstet Gynecol 67(5):735–737

    Article  CAS  PubMed  Google Scholar 

  • Lassaletta L, Fonkalsrud EW, Tovar JA, Dudgeon D, Asch MJ (1975) Management of umbilical hernias in infancy and childhood. J Pediatr Surg 10(3):405–409

    Article  CAS  PubMed  Google Scholar 

  • Lau WD, Ong CH, Lim TP, Teo C (2015) Penile cancer: a local case series and literature review. Singap Med J 56(11):637–640

    Article  Google Scholar 

  • Lee T, Choi HR, Lee YT, Lee YH (1994) Paraffinoma of the penis. Yonsei Med J 35(3):344–348

    Article  CAS  PubMed  Google Scholar 

  • Lee JH, Kim MY, Kim HO, Park YM (2005) Nevoid acanthosis nigricans localized to umbilicus: successful treatment with topical tretinoin. Ann Dermatol 17:24–26

    Article  Google Scholar 

  • Lee MY, Dalpiaz A, Schwamb R, Miao Y, Waltzer W, Khan A (2015) Clinical pathology of Bartholin’s glands: a review of the literature. Curr Urol 8(1):22–25

    Article  PubMed  PubMed Central  Google Scholar 

  • Lerch M, Mainetti C, Terziroli Beretta-Piccoli B, Harr T (2018) Current perspectives on erythema multiforme. Clin Rev Allergy Immunol 54(1):177–184

    Article  CAS  PubMed  Google Scholar 

  • Lestringant GG, Qayed KI, Fletcher S (1991) Is the incidence of trichomycosis of genital hair underestimated? J Am Acad Dermatol 24(2 Pt 1):297–298

    Article  CAS  PubMed  Google Scholar 

  • Levell NJ, Bewly AP, Levene GM (1994) Porokeratosis of Mibelli on the penis, scrotum and natal cleft. Clin Exp Dermatol 19(1):77–78

    Article  CAS  PubMed  Google Scholar 

  • Li X, Hong W, Xu A (2014) Two cases of focal scrotal vitiligo successfully treated by autologous cultured melanocyte transplantation. Dermatol Ther (Heidelb) 4(1):141–144

    Article  Google Scholar 

  • Li F, Xu Y, Wang H, Chen B, Wang Z, Zhao Y, Zhu S, Chen G (2015) Diagnosis and treatment of penile verrucous carcinoma. Oncol Lett 9(4):1687–1690

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Lisboa C, Ferreira A, Resende C, Rodrigues AG (2009) Infectious balanoposthitis: management, clinical and laboratory features. Int J Dermatol 48(2):121–124

    Article  PubMed  Google Scholar 

  • Lloyd J, Crouch NS, Minto CL, Liao LM, Creighton SM (2005) Female genital appearance: “normality” unfolds. BJOG 112(5):643–646

    Article  PubMed  Google Scholar 

  • Lopes LC, Lobo L, Bajanca R (2003) Perforating calcific elastosis. J Eur Acad Dermatol Venereol 17(2):206–207

    Article  PubMed  Google Scholar 

  • Lotan G, Klin B, Efrati Y (2002) Double-ligature: a treatment for pedunculated umbilical granulomas in children. Am Fam Physician 65(10):2067–2068

    PubMed  Google Scholar 

  • Lowitt MH, Kariniemi AL, Niemi KM, Kao GF (1996) Cutaneous malacoplakia: a report of two cases and review of the literature. J Am Acad Dermatol 34(2 Pt 2):325–332

    Article  CAS  PubMed  Google Scholar 

  • Lynch PJ, Edwards L (2011) Genital dermatology atlas, 2nd edn. Lippincott Williams & Wilkins, Philadelphia

    Google Scholar 

  • Magana ML, Alcántara A, Perez-Martin MA (2004) Histopathology of cutaneous amebiasis. Am J Dermatopathol 26(4):280–284

    Article  PubMed  Google Scholar 

  • Magro CM, Simman R, Jackson S (2010) Calciphylaxis: a review. J Am Col Certif Wound Spec 2(4):66–72

    PubMed  Google Scholar 

  • Mahadevappa N, Kochhar G, Vilvapathy KS, Dharwadkar S, Kumar S (2016) Self-inflicted foreign bodies in lower genitourinary tract in males: our experience and review of literature. Urol Ann 8(3):338–342

    Article  PubMed  PubMed Central  Google Scholar 

  • Mahdi HR, El Hennawy HM (2009) Omphalolith presented with peritonitis: a case report. Cases J 2:8191

    Article  PubMed  PubMed Central  Google Scholar 

  • Maldonado VA (2014) Benign vulvar tumors. Best Pract Res Clin Obstet Gynaecol 28(7):1088–1097

    Article  PubMed  Google Scholar 

  • Malhotra MK, Singh KB, Garg P, Sharma P, Singh K (2015) Mucoid cyst of the penis: a case report. J Clin Diagn Res 9(2):PD01–PD02

    PubMed  PubMed Central  Google Scholar 

  • Malik M, Ahmed AR (2005) Involvement of the female genital tract in pemphigus vulgaris. Obstet Gynecol 106(5 Pt 1):1005–1012

    Article  PubMed  Google Scholar 

  • Mappes HJ, Farthmann EH (2001) Anal abscess and fistula. In: Holzheimer RG, Mannick JA (eds) Surgical treatment: evidence-based and problem-oriented. Zuckschwerdt, Munich

    Google Scholar 

  • Marren P, Wojnarowska F, Venning V, Wilson C, Nayar M (1993) Vulvar involvement in auto-immune bullous diseases. J Reprod Med 38:101–107

    CAS  PubMed  Google Scholar 

  • Marren P, Walkden V, Mallon E, Wojnarowska F (1996) Vulval cicatricial pemphigoid may mimic lichen sclerosus. Br J Dermatol 134(3):522–524

    Article  CAS  PubMed  Google Scholar 

  • Martin Lopez JE (2015) Candidiasis (vulvovaginal). BMJ Clinical Evidence 2015:0815

    PubMed  PubMed Central  Google Scholar 

  • Martin JM, Molina I, Monteagudo C, Marti N, Lopez V, Jorda E (2008) Buschke-Lowenstein tumor. J Dermatol Case Rep 2(4):60–62

    Article  PubMed  PubMed Central  Google Scholar 

  • Martorell A, García-Martínez FJ, Jiménez-Gallo D, Pascual JC, Pereyra-Rodriguez J, Salgado L, Vilarrasa E (2015) An update on hidradenitis suppurativa (part I): epidemiology, clinical aspects, and definition of disease severity. Actas Dermosifiliogr 106(9):703–715

    Article  CAS  PubMed  Google Scholar 

  • Marzano AV, Vezzoli P, Berti E (2013) Skin involvement in cutaneous and systemic vasculitis. Autoimmun Rev 12(4):467–476

    Article  PubMed  Google Scholar 

  • Mashayekhi S, Flohr C, Lewis FM (2017) The treatment of vulval lichen sclerosus in prepubertal girls: a critically appraised topic. Br J Dermatol 176(2):307–316

    Article  CAS  PubMed  Google Scholar 

  • Mason WH, Andrews R, Ross LA, Wright HT Jr (1989) Omphalitis in the newborn infant. Pediatr Infect Dis J 8(8):521–525

    Article  CAS  PubMed  Google Scholar 

  • Massone C, Belachew WA, Schettini A (2015) Histopathology of the lepromatous skin biopsy. Clin Dermatol 33(1):38–45

    Article  PubMed  Google Scholar 

  • Mathur SK, Bhargava P (1997) Insulin resistence and skin tags. Dermatology 195(2):184

    Article  CAS  PubMed  Google Scholar 

  • Matuszewski M, Michajłowski I, Michajłowski J, Sokołowska-Wojdyło M, Włodarczyk A, Krajka K (2009) Topical treatment of bowenoid papulosis of the penis with imiquimod. J Eur Acad Dermatol Venereol 23:978–979

    Article  CAS  PubMed  Google Scholar 

  • Matz H, Orion E, Wolf R (2006) Pruritic urticarial papules and plaques of pregnancy: polymorphic eruption of pregnancy (PUPPP). Clin Dermatol 24(2):105–108

    Article  PubMed  Google Scholar 

  • McDougal WS (2003) Lymphedema of the external genitalia. J Urol 170(3):711–716

    Article  PubMed  Google Scholar 

  • McGregor TB, Pike JG, Leonard MP (2007) Pathologic and physiologic phimosis: approach to the phimotic foreskin. Can Fam Physician 53(3):445–448

    PubMed  PubMed Central  Google Scholar 

  • Meeuwis KA, de Hullu JA, Massuger LF, van de Kerkhof PC, van Rossum MM (2011) Genital psoriasis: a systematic literature review on this hidden skin disease. Acta Derm Venereol 91(1):5–11

    Article  PubMed  Google Scholar 

  • Mehrtens SH, Crawley JM (2015) Pyoderma gangrenosum. Br J Hosp Med (Lond) 76(11):C173–C176

    Article  CAS  Google Scholar 

  • Mehta V, Nayak S, Balachandran C, Monga P, Rao R (2010) Extensive congenital vulvar lymphangioma mimicking genital warts. Indian J Dermatol 55(1):121–122

    Article  PubMed  PubMed Central  Google Scholar 

  • Menter A, Griffiths CE (2007) Current and future management of psoriasis. Lancet 370(9583):272–284

    Article  CAS  PubMed  Google Scholar 

  • Merkley K (2005) Vulvovaginitis and vaginal discharge in the pediatric patient. J Emerg Nursing 31(4):400–402

    Article  Google Scholar 

  • Micali G, Lacarrubba F, Dinotta F, Massimino D, Nasca MR (2010) Treating skin cancer with topical cream. Expert Opin Pharmacother 11(9):1515–1527

    Article  CAS  PubMed  Google Scholar 

  • Micali G, Cusini M, Donofrio P, Dinotta F (2013) Atlas of male genital disorders: a useful aid for clinical diagnosis. Springer, Milan

    Book  Google Scholar 

  • Michajłowski I, Sobjanek M, Michajłowski J, Włodarkiewicz A, Matuszewski M (2012) Normal variants in patients consulted in the dermatology clinic for lesions of the male external genitalia. Cent European 65(1):17–20

    Google Scholar 

  • Mimura MA, Hirota SK, Sugaya NN, Sanches JA jr, Migliari DA (2009) Systemic treatment in severe cases of recurrent aphthous stomatitis: an open trial. Clinics (Sao Paulo, Brazil) 64(3): 193–198

    Article  PubMed  PubMed Central  Google Scholar 

  • Min KW, Park SY, Paik SS (2012) Penile actinomycosis clinically diagnosed as an epidermal cyst: a case report. Ann R Coll Surg Engl 94(1):e22–e23

    Article  PubMed  Google Scholar 

  • Mirheydar HS, Friedlander SF, Kaplan GW (2014) Prepubertal male genitourinary metastatic Crohn’s disease: report of a case and review of literature. Urology 83(5):1165–1169

    Article  PubMed  Google Scholar 

  • Mirza M, Zamilpa I, Wilson JM (2008) Localized penile bullous pemphigoid of childhood. J Pediatr Urol 4(5):395–397

    Article  PubMed  Google Scholar 

  • Mohsin SK, Lee MW, Amin MB, Stoler MH, Eyzaguirre E, Ma CK, Zarbo RJ (1998) Cutaneous verruciform xanthoma: a report of five cases investigating the etiology and nature of xanthomatous cells. Am J Surg Pathol 22(4):479–487

    Article  CAS  PubMed  Google Scholar 

  • Moore WM, Stokes TL, Cabanas VY (1973) Malakoplakia of the skin: report of a case. Am J Clin Pathol 60(2):218–221

    Article  PubMed  Google Scholar 

  • Mora M, Boccardo F, Campisi C, Carli C, Ricca R, Fulcheri E (2010) Vulvar sebaceous hyperplasia associated with lymphedema of external genitalia. Int J Dermatol 49(1):70–74

    Article  PubMed  Google Scholar 

  • Mortazavi H, Taheri A, Mansoori P, Kani ZA (2005) Localized forms of steatocystoma multiplex: case report and review of the literature. Dermatol Online J 11(1):22

    PubMed  Google Scholar 

  • Mulekar SV, Al Issa A, Al Eisa A, Asaad M (2005) Genital vitiligo treated by autologous, noncultured melanocyte-keratinocyte cell transplantation. Dermatol Surg 31(12):1737–1739

    CAS  PubMed  Google Scholar 

  • Murphy R (2004) Desquamative inflammatory vaginitis. Dermatol Ther 17(1):47–49

    Article  PubMed  Google Scholar 

  • Murshid KR (1996) Pilonidal sinus: primary closure with low recurrence. Emirates Med J 14:96–100

    Google Scholar 

  • Muscat M, Brincat M, Degaetano J, Vassallo J, Calleja-Agius J (2013) An unusual site for calciphylaxis: a case report. Gynecol Endocrinol 29(2):91–92

    Article  PubMed  Google Scholar 

  • Nagar H (2001) Umbilical granuloma: a new approach to an old problem. Paediatric Surg Int 17(7):513–514

    Article  CAS  Google Scholar 

  • Nagore E, Sanchez-Motilla JM, Febrer MI, Aliaga A (1998) Median raphe cysts of the penis: a report of five cases. Pediatr Dermatol 15(3):191–193

    Article  CAS  PubMed  Google Scholar 

  • Nakib G, Calcaterra V, Pelizzo G (2017) Longstanding presence of a vaginal foreign body (battery): severe stenosis in a 13-year-old girl. J Pediatr Adolesc Gynecol 30(1):e15–e18

    Article  PubMed  Google Scholar 

  • Nasu K, Okamoto M, Nishida M, Narahara H (2013) Perineal endometriosis. J Obstet Gynaecol Res 39(5):1095–1097

    Article  PubMed  Google Scholar 

  • Navarrete S, Sánchez Ismayel A, Sanchez Salas R, Sánchez R, Navarrete Llopis S (2005) Treatment of urachal anomalies: a minimally invasive surgery technique. JSLS 9(4):422–425

    PubMed  Google Scholar 

  • Nayak SU, Shenoi SD, Bhat ST, Shivamurthy A (2015) Bowenoid papulosis. Indian J Sex Transm Dis 36(2):223–225

    Article  Google Scholar 

  • Neill SM, Lewis FM (2008) Vulvovaginal lichen planus: a disease in need of a unified approach. Arch Dermatol 144(11):1502–1503

    Article  PubMed  Google Scholar 

  • Nittala PP (2009) Omphalolith/umbolith: CT and MR imaging appearances in two patients. Singap Med J 50(7):745–746

    Google Scholar 

  • Odukogbe AA, Afolabi BB, Bello OO, Adeyanju AS (2017) Female genital mutilation/cutting in Africa. Transl Androl Urol 6(2):138–148

    Article  PubMed  PubMed Central  Google Scholar 

  • Olcay A, Yeliz E, Gulen D, Sabri E (2007) Primary umbilical adenocarcinoma: case report and review of the literature. Am Surg 73(9):923–925

    Google Scholar 

  • Omole F, Simmons BJ, Hacker Y (2003) Management of Bartholin’s duct cyst and gland abscess. Am Fam Physician 68(1):135–140

    PubMed  Google Scholar 

  • Omprakash HM, Rajendran SC (2008) Lymphangioma circumscriptum (microcystic lymphatic malformation): palliative coagulation using radiofrequency current. J Cutan Aesthet Surg 1(2):85–88

    Article  PubMed Central  Google Scholar 

  • Pacilli M, Sebire NJ, Maritsi D, Kiely EM, Drake DP, Curry JI, Pierro A (2007) Umbilical polyp in infants and children. Eur J Pediatr Surg 17(6):397–399

    Article  CAS  PubMed  Google Scholar 

  • Pals Jr VM, Santora T, Rukstalis DB, Sollender GE (2018) Fournier gangrene. Resource document. http://emedicine.medscape.com/article/2028899-overview. Accessed 18 Mar 2018

  • Panagiotopoulou N, Wong CS, Winter-Roach B (2010) Vulvovaginal-gingival syndrome. J Obstet Gynaecol 30(3):226–230

    Article  CAS  PubMed  Google Scholar 

  • Paradise JE, Willis ED (1985) Probability of vaginal foreign body in girls with genital complaints. Am J Dis Child 139:472–476

    CAS  PubMed  Google Scholar 

  • Parikh RP, Upadhyay KJ (2013) Cullen’s sign for acute haemorrhagic pancreatitis. Indian J Med Res 137(6):1210

    PubMed  PubMed Central  Google Scholar 

  • Parlakgumus A, Canpolat ET, Caliskan K, Colakoglu T, Yıldırım S, Ezer A, Noyan T (2008) Scrotal calcinosis due to resorption of cyst walls: a case report. J Med Case Rep 2:375

    Article  PubMed  PubMed Central  Google Scholar 

  • Parshad S, Grover PS, Sharma A, Verma DK, Sharma A (2002) Primary cutaneous amoebiasis: case report with review of the literature. Int J Dermatol 41(10):676–680

    Article  PubMed  Google Scholar 

  • Pastar Z, Rados J, Lipozencić J, Skerlev M, Loncarić D (2004) Zoon plasma cell balanitis: an overview and role of histopathology. Acta Dermatovenerol Croat 12(4):268–273

    PubMed  Google Scholar 

  • Paydary K, Emamzadeh Fard S, Mahboubi AH, Ziaee V, Moradinejad MH, Kajbafzadeh AM (2015) Penile skin involvement as the first presentation of Henoch-Schonlein purpura report of nine cases and review of literature. Iran J Pediatr 25(4):e2177

    Article  PubMed  PubMed Central  Google Scholar 

  • Payette MJ, Weston G, Humphrey S, Yu J, Holland KE (2015) Lichen planus and other lichenoid dermatoses: kids are not just little people. Clin Dermatol 33(6):631–643

    Article  PubMed  Google Scholar 

  • Peng WS, Tan C (2016) Bowenoid papulosis in a linear distribution. Postepy Dermatol 33(2):146–148

    Google Scholar 

  • Perry D, Lynch PJ, Fazel N (2008) Pseudoepitheliomatous, keratotic, and micaceous balanitis: case report and review of the literature. Dermatol Nurs 20(2):117–120

    PubMed  Google Scholar 

  • Petersson F, Mjörnberg PA, Kazakov DV, Bisceglia M (2009) Eruptive syringoma of the penis. A report of 2 cases and a review of the literature. Am J Dermatopathol 31(5):436–438

    Article  PubMed  Google Scholar 

  • Phiske MM (2014) An approach to acanthosis nigricans. Indian Dermatol Online J 5(3):239–249

    Article  PubMed  PubMed Central  Google Scholar 

  • Piette EW, Rosenbach M (2016a) Granuloma annulare: clinical and histologic variants, epidemiology, and genetics. J Am Acad Dermatol 75(3):457–465

    Article  PubMed  Google Scholar 

  • Piette EW, Rosenbach M (2016b) Granuloma annulare: pathogenesis, disease associations and triggers, and therapeutic options. J Am Acad Dermatol 75(3):467–479

    Article  PubMed  Google Scholar 

  • Pinto e Silva MP, Bassani MA, Miquelutti MA, Marques Ade A, do Amaral MT, de Oliveira MM, Ferreira Nde O (2015) Manual lymphatic drainage and multilayer compression therapy for vulvar edema: a case series. Physiother Theory Pract 31(7):527–531

    Article  PubMed  Google Scholar 

  • Podolej GS, Babcock C (2017) Emergency department management of priapism. Emerg Med Pract 19(1):1–16

    PubMed  Google Scholar 

  • Porter WM, Du P, Menagı H, Philip G, Bunker CB (2001) Porokeratosis of the penis. Br J Dermatol 144(3):643–644

    Article  CAS  PubMed  Google Scholar 

  • Prens E, Deckers I (2015) Pathophysiology of hidradenitis suppurativa: an update. J Am Acad Dermatol 73(5 Suppl 1):S8–S11

    Article  CAS  PubMed  Google Scholar 

  • Pulido-Pérez A, Avilés-Izquierdo JA, Suárez-Fernández R (2012) Cutaneous vasculitis. Actas Dermosifiliogr 103(3):179–191

    Article  PubMed  Google Scholar 

  • Quddus MR, Rashid LB, Sung CJ, Robinson-Bostom L, Lawrence WD (2010) Atypical melanocytic nevi of genital type: a distinctive pigmented lesion on the genital tract often confused with malignant melanoma. Dermatol Online J 16(2):9

    PubMed  Google Scholar 

  • Rahbour G, Ullah MR, Yassin N, Thomas GP (2012) Cullen’s sign- case report with a review of the literature. Int J Surg Case Rep 3(5):143–146

    Article  PubMed  PubMed Central  Google Scholar 

  • Ran NA, Payne AS (2017) Rituximab therapy in pemphigus and other autoantibody-mediated diseases. F1000Res 6:83

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Rane V, Read T (2013) Penile appearance, lumps and bumps. Aust Fam Physician 42(5):270–274

    PubMed  Google Scholar 

  • Rao NR (1969) Malacoplakia of broad ligament, inguinal region, and endometrium. Arch Pathol 88(1):85–88

    CAS  PubMed  Google Scholar 

  • Raymond PL (1990) The ubiquitous umbilicus: what it can reveal about intra-abdominal disease. Postgrad Med 87(2):175–181

    Article  CAS  PubMed  Google Scholar 

  • Retamar RA, Kien MC, Chouela EN (2003) Zoon’s balanitis: presentation of 15 patients, five treated with a carbon dioxide laser. Int J Dermatol 42(4):305–307

    Article  PubMed  Google Scholar 

  • Robinson JB, Im DD, Jockle G, Rosenshein NB (1999) Vulvar porokeratosis: case report and review of the literature. Int J Gynecol Pathol 18(2):169–173

    Article  CAS  PubMed  Google Scholar 

  • Roewe RJ, Uhlman MA, Bockholt NA, Gupta A (2014) Basal cell carcinoma of the penis: a case report and review of the literature. Case Rep Urol 2014:173076

    CAS  PubMed  PubMed Central  Google Scholar 

  • Ronan SG, Reddy RL, Manaligod JR, Alexander J, Fu T (1989) Disseminated strongyloidiasis presenting as purpura. J Am Acad Dermatol 21(5 Pt 2):1123–1125

    Article  CAS  PubMed  Google Scholar 

  • Rowe MI, O’Neil JA Jr, Grosfeld JL, Fonkalsrud EW, Coran AG (1995) Disorders of the umbilicus. In: Rowe MI (ed) Essentials of pediatric surgery. Mosby, New York, pp 441–445

    Google Scholar 

  • Rubenstein RA, Dogra VS, Seftel AD, Resnick MI (2004) Benign intrascrotal lesions. J Urol 171(5):1765–1772

    Article  PubMed  Google Scholar 

  • Rudolph CM, Al-Fares S, Vaughan-Jones SA, Müllegger RR, Kerl H, Black MM (2006) Polymorphic eruption of pregnancy: clinicopathology and potential trigger factors in 181 patients. Br J Dermatol 154(1):54–60

    Article  CAS  PubMed  Google Scholar 

  • Sachdeva S (2008) The dermatoses of pregnancy. Indian J Dermatol 53(3):103–105

    Article  PubMed  PubMed Central  Google Scholar 

  • Saladi RN, Persaud AN, Phelps RG, Cohen SR (2004) Scrotal calcinosis: is the cause still unknown? J Am Acad Dermatol 51(2 Suppl):S97–S101

    Article  PubMed  Google Scholar 

  • Salluh JI, Bozza FA, Pinto TS, Toscano L, Weller PF, Soares M (2005) Cutaneous periumbilical purpura in disseminated strongyloidiasis in cancer patients: a pathognomonic feature of potentially lethal disease? Braz J Infect Dis 9(5):419–424

    Article  PubMed  Google Scholar 

  • Salonia A, Eardley I, Giuliano F, Hatzichristou D, Moncada I, Vardi Y, Wespes E, Hatzimouratidis K (2014) European association of urology guidelines on priapism. Eur Urol 65(2):480–489

    Article  PubMed  Google Scholar 

  • Sampaio AL, Mameri AC, Vargas TJ, Ramos-e-Silva M, Nunes AP, Carneiro SC (2011) Seborrheic dermatitis. An Bras Dermatol 86(6):1061–1071

    Article  PubMed  Google Scholar 

  • Sand FL, Thomsen SF (2017) Skin diseases of the vulva: infectious diseases. J Obstet Gynaecol 37(7):840–848

    Article  PubMed  Google Scholar 

  • Sandhu R, Min Z, Bhanot N (2014) A gigantic anogenital lesion: buschke-lowenstein tumor. Case Rep Dermatol Med 2014:650714

    PubMed  PubMed Central  Google Scholar 

  • Sardana K, Chakravarty P, Goel K (2014) Optimal management of common acquired melanocytic nevi (moles): current perspectives. Clin Cosmet Investig Dermatol 7:89–103

    Article  PubMed  PubMed Central  Google Scholar 

  • Sardesai VR, Agarwal TD, Dalal AB, Mhatre MA (2013) Pseudoepitheliomatous keratotic and micaceous balanitis with malignant transformation. Indian J Sex Transm Dis 34(1):38–40

    Article  Google Scholar 

  • Sarifakioglu E, Erdal E, Gunduz C (2006) Vestibular papillomatosis: case report and literature review. Acta Dermatol Venereol 86(2):177–178

    Google Scholar 

  • Sarkell B, Dannenberg M, Blaylock WK, Patterson JW (1994) Cutaneous malacoplakia. J Am Acad Dermatol 30(5 Pt 2):834–836

    Article  CAS  PubMed  Google Scholar 

  • Sasso F, Gulino G, Basar M, Carbone A, Torricelli P, Alcini E (1996) Penile Mondors disease: an underestimated pathology. Br J Urol 77(5):729–732

    Article  CAS  PubMed  Google Scholar 

  • Satoh M, Yamamoto T (2013) Genital pyoderma gangrenosum: report of two cases and published work review of Japanese cases. J Dermatol 40(10):840–843

    PubMed  Google Scholar 

  • Saúl A (1982) Amoebiasis cutis. Inter J Dermatol 21(8):472–475

    Article  Google Scholar 

  • Scheinfeld N (2014) An atlas of the morphological manifestations of hidradenitis suppurativa. Dermatol Online J 20(4):22373

    PubMed  Google Scholar 

  • Schwartz RA (1994) Acanthosis nigricans. J Am Acad Dermatol 31(1):1–19

    Article  CAS  PubMed  Google Scholar 

  • Scott GR, Chosidow O, IUSTI/WHO (2010) European guideline for the management of pediculosis pubis, 2010. Int J STD AIDS 22(6):304–305

    Article  Google Scholar 

  • Sehgal VN, Srivastava G (2006) Fixed drug eruption; changing scenario of incriminating drugs. Int J Dermatol 45(8):897–908

    Article  CAS  PubMed  Google Scholar 

  • Sengupta S, Das JK, Gangopadhyay A (2008) Porokeratosis confined to the genital area: a report of three cases. Indian J Dermatol Venereol Leprol 74(1):80

    Article  PubMed  Google Scholar 

  • Serour GI (2013) Medicalization of female genital mutilation/cutting. Afr J Urol 19(3):145–149

    Article  Google Scholar 

  • Servelle M (1987) Surgical treatment of lymphedema: a report on 652 cases. Surgery 101(4):485–495

    CAS  PubMed  Google Scholar 

  • Shafer WG (1971) Verruciform xanthoma. Oral Surg Oral Med Oral Pathol 31(3):784–789

    Article  CAS  PubMed  Google Scholar 

  • Shahid SK (2012) Phimosis in children. ISRN Urol 2012:707329

    PubMed  PubMed Central  Google Scholar 

  • Shao IH, Chen TD, Shao HT, Chen HW (2012) Male median raphe cysts: serial retrospective analysis and histopathological classification. Diagn Pathol 7:121

    Article  PubMed  PubMed Central  Google Scholar 

  • Sharma JB (2015) Current diagnosis and management of female genital tuberculosis. J Obstet Gynaecol India 65(6):362–371

    Article  PubMed  PubMed Central  Google Scholar 

  • Sharma B, Raina S (2015) Caput medusae. Indian J Med Res 141(4):494

    Article  PubMed  PubMed Central  Google Scholar 

  • Sheehan D, Hussain S, Vijayaraghavan G (2011) Umbilical Concretion. J Radiol Case Rep 5(4):25–31

    PubMed  PubMed Central  Google Scholar 

  • Shelley-Fraser G, Borley NR, Warren BF, Shepherd NA (2012) The connective tissue changes of Crohn’s disease. Histopathology 60(7):1034–1044

    Article  PubMed  Google Scholar 

  • Shenfeld OZ, Gnessin E (2011) Management of urogenital trauma: state of the art. Curr Opin Urol 21(6):449–454

    Article  PubMed  Google Scholar 

  • Sherry L, Kean R, McKloud E, O’Donnell LE, Metcalfe R, Jones BL, Ramage G (2017) Biofilms formed by isolates from recurrent vulvovaginal candidiasis patients are heterogeneous and insensitive to fluconazole. Antimicrob Agents Chemother 61(9). pii: e01065-17

    Google Scholar 

  • Shiryazdi SM, Heiranizadeh N, Soltani HR (2013) Rectorrhagia and vaginal discharge caused by a vaginal foreign body – a case report and review of literature. J Pediatr Adolesc Gynecol 26(3):e73–e75

    Article  CAS  PubMed  Google Scholar 

  • Siddiqi S, Vijay V, Ward M, Mahendran R, Warren S (2008) Pruritus Ani. Ann R Coll Surg Engl 90(6):457–463

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Simon DA, Berry S, Brannian J, Hansen K (2003) Recurrent, purulent vaginal discharge with long standing presence of a foreign body and vaginal stenosis. J Pediatr Adolosc Gynecol 16(6):361–363

    Article  Google Scholar 

  • Singh N, Thappa DM (2008) Circinate pustular psoriasis localized to glans penis mimicking ‘circinate balanitis’ and responsive to dapsone. Indian J Dermatol Venereol Leprol 74(4):388–389

    Article  PubMed  Google Scholar 

  • Singh S, Singh P, Singh RJ (2010) Persistent urogenital sinus. J Anat Soc India 59(2):242–244

    Article  Google Scholar 

  • Singh A, Ahmed K, Aydin A, Khan MS, Dasgupta P (2016) Fournier’s gangrene. A clinical review. Arch Ital Urol Androl 88(3):157–164

    Article  PubMed  Google Scholar 

  • Sinha S, Schwartz RA (2007) Juvenile acanthosis nigricans. J Am Acad Dermatol 57(3):502–508

    Article  PubMed  Google Scholar 

  • Sinnya S, Wheller L, Carroll M, Williamson R, De’Ambrosis B (2015) Verruciform xanthoma of the penis: a rare Australian case. Australas J Dermatol 56(4):e99–e101

    Article  PubMed  Google Scholar 

  • Smeltzer DM, Stickler GB, Schirger A (1985) Primary lymphedema in children and adolescents: a follow-up study and review. Pediatrics 76(2):206–218

    CAS  PubMed  Google Scholar 

  • Snider RL (1992) Verruciform xanthomas and lymphedema. J Am Acad Dermatol 27(6 Pt 1):1021–1123

    Article  CAS  PubMed  Google Scholar 

  • Sobel JD (2007) Vulvovaginal candidosis. Lancet 369(9577):1961–1971

    Article  PubMed  Google Scholar 

  • Spinillo A, Capuzzo E, Nicola S, Baltaro F, Ferrari A, Monaco A (1995) The impact of oral contraception on vulvovaginal candidiasis. Contraception 51(5):293–297

    Article  CAS  PubMed  Google Scholar 

  • Steck WD, Helwig EB (1965) Tumors of the umbilicus. Cancer 18:907–915

    Article  CAS  PubMed  Google Scholar 

  • Stieger M, Pelivani N, Ramelet AA, Beltraminelli H, Borradori L (2013) Penile erosions as first manifestation of pemphigus vulgaris: a misleading presentation. Acta Derm Venereol 93(2):248–249

    Article  PubMed  Google Scholar 

  • Subbotin VM, Davidov MI, Abdrashitov RR, Rylov IL, Sholin NV (2000) Foreign bodies in rectum. Vestn Khir Im I I Grek 159:91–95

    CAS  PubMed  Google Scholar 

  • Swanson SL, Woosley JT, Fleischer AB Jr, Crosby DL (1992) Umbilical mass. Omphalolith. Arch Dermatol 128(9): 1265, 1270

    Article  Google Scholar 

  • Swaroop MR, Manas SN, Nischal KC, Sathyanarayana BD, Basavaraj HB (2014) Multiple Bowen’s disease over the right gluteal region in a middle-aged male. Indian J Dermatopathol Diagn Dermatol 1:97–98

    Article  Google Scholar 

  • Swierzewski SJ 3rd, Denil J, Ohi DA (1993) The management of penile Mondor’s phlebitis: superficial dorsal penile thromboses. J Urol 150(1):77–78

    Article  PubMed  Google Scholar 

  • Tagliolatto S, Santos Neto Ode O, Alchorne MM, Enokihara MY (2015) Sebaceous hyperplasia: systemic treatment with isotretinoin. An Bras Dermatol 90(2):211–215

    Article  PubMed  PubMed Central  Google Scholar 

  • Talhari C, Talhari S, Penna GO (2015) Clinical aspects of leprosy. Clin Dermatol 33(1):26–37

    Article  PubMed  Google Scholar 

  • Tay EY, Ho MS, Chandran NS, Lee JS, Heng YK (2015) Lichen nitidus presenting with nail changes – case report and review of the literature. Pediatr Dermatol 32(3):386–388

    Article  PubMed  Google Scholar 

  • Teichman JMH, Mannas M, Elston DM (2018) Noninfectious penile lesions. Am Fam Physician 97(2):102–110

    PubMed  Google Scholar 

  • Terlecki RP, Santucci RA (2015). Phimosis, adult circumcision, and buried penis. Resource document. http://emedicine.medscape.com/article/442617-overview. Accessed 14 Oct 2017

  • Thomazeau H, Alno L, Lobel B (1983) Thrombosis of the dorsal vein of the penis: apropos of two cases. J Urol (Paris) 89(9):691–692

    CAS  Google Scholar 

  • Thwaini A, Khan A, Malik A, Cherian J, Barua J, Shergill I, Mammen K (2006) Fournier’s gangrene and its emergency management. Postgrad Med J 82(970):516–519

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Thyssen JP, Skare L, Lundgren L, Menné T, Johansen JD, Maibach HI, Lidén C (2010) Sensitivity and specificity of the nickel spot (dimethylglyoxime) test. Contact Dermatitis 62(5):279–288

    Article  PubMed  Google Scholar 

  • Tiwary AK, Kumar P, Agrawal S (2017) Palmoplantar, genital and lip involvement in a de novo case of histoid leprosy. Lepr Rev 88:280–284

    Google Scholar 

  • Tonolini M, Villa C, Campari A, Ravelli A, Bianco R, Cornalba G (2013) Common and unusual urogenital Crohn’s disease complications: spectrum of cross-sectional imaging findings. Abdom Imaging 38(1):32–41

    Article  PubMed  Google Scholar 

  • Tüzün Y, Wolf R, Bağlam S, Engin B (2015) Diaper (napkin) dermatitis: a fold (intertriginous) dermatosis. Clin Dermatol 33(4):477–482

    Article  PubMed  Google Scholar 

  • Udager AM, Frisch NK, Hong LJ, Stasenko M, Johnston CM, Liu JR, Chan MP, Harms PW, Fullen DR, Orsini A, Thomas DG, Lowe L, Patel RM (2017) Gynecologic melanomas: a clinicopathologic and molecular analysis. Gynecol Oncol 147(2):351–357

    Article  CAS  PubMed  Google Scholar 

  • Uppert JS, Gerber MA, Deitch HR, Mortensen JE, Staat MA, Adams Hillard PJ (2006) Vulvar ulcers in young females: a manifestation of aphthosis. J Pediatr Adolesc Gynecol 19(3):195–204

    Article  Google Scholar 

  • Urbano FL (2001) Sister Joseph’s nodule. Hosp Physician 37(5):33–35

    Google Scholar 

  • Valour F, Sénéchal A, Dupieux C, Karsenty J, Lustig S, Breton P, Gleizal A, Boussel L, Laurent F, Braun E, Chidiac C, Ader F, Ferry T (2014) Actinomycosis: etiology, clinical features, diagnosis, treatment, and management. Infect Drug Resist 7:183–197

    PubMed  PubMed Central  Google Scholar 

  • van der Voort HJ, ten Velden JA, Wassenaar RP, Silberbusch J (1996) Malacoplakia: two case reports and a comparison of treatment modalities based on a literature review. Arch Intern Med 156(5):577–583

    Article  PubMed  Google Scholar 

  • van der Zanden LF, van Rooij IA, Feitz WF, Franke B, Knoers NV, Roeleveld N (2012) Aetiology of hypospadias: a systematic review of genes and environment. Hum Reprod Update 18(3):260–283

    Article  PubMed  CAS  Google Scholar 

  • Vazmitel M, Spagnolo DV, Nemcova J, Michal M, Kazakov DV (2008) Hidradenoma papilliferum with a ductal carcinoma in situ component: case report and review of literature. Am J Dermatopathol 30(40):392–394

    Article  PubMed  Google Scholar 

  • Vázquez-Osorio I, Salgado-Boquete L, Espasandín-Arias M, García-Martínez FJ, Sánchez-Aguilar D, Toribio J (2014) Scrotal bullous pemphigoid in an elderly patient. Int J Dermatol 53(9):e389–e390

    Article  PubMed  Google Scholar 

  • Veeranna S, Kushalappa, Betkerur J, Savitha (2006) Periumbilical keratotic papules. Indian J Dermatol Venereol Leprol 72(2):178

    Article  CAS  PubMed  Google Scholar 

  • Velasco E (1993) Mucoid cyst of penis skin. Urol colomb 3:99–104

    Google Scholar 

  • Venyo AK (2015) Tuberculosis of the penis: a review of the literature. Scientifica (Cairo) 2015:601624

    Google Scholar 

  • Verma SB, Vasani R (2016) Male genital dermatophytosis – clinical features and the effects of the misuse of topical steroids and steroid combinations – an alarming problem in India. Mycoses 59(10):606–614

    Article  PubMed  Google Scholar 

  • Viana ACL, Gontijo B, Bittencourt FV (2013) Giant congenital melanocytic nevus. An Bras Dermatol 88(6):863–878

    Article  PubMed  PubMed Central  Google Scholar 

  • Villa L, Varela JA, Otero L, Sánchez C, Junquera ML, Río JS, Vázquez F (2010) Molluscum contagiosum: a 20-year study in a sexually transmitted infections unit. Sex Transm Dis 37(7):423–424

    PubMed  Google Scholar 

  • Virgili A, Mantovani L, Lauriola MM, Marzola A, Corazza M (2008) Tacrolimus 0.1% ointment: is it really effective in plasma cell vulvitis? Report of four cases. Dermatology 216(3):243–246

    Article  CAS  PubMed  Google Scholar 

  • Vyas A (2017) Genital lichen sclerosus and its mimics. Obstet Gynecol Clin N Am 44(3):389–406

    Article  Google Scholar 

  • Wang C, Lin A (2014) Efficacy of topical calcineurin inhibitors in psoriasis. J Cutan Med Surg 18(1):8–14

    Article  CAS  PubMed  Google Scholar 

  • Wechter ME, Wu JM, Marzano D, Haefner H (2009) Management of Bartholin duct cysts and abscesses: a systematic review. Obstet Gynecol Surv 64(6):395–404

    Article  PubMed  Google Scholar 

  • Wollina U, Verma S (2010) Vulvar vestibular papillomatosis. Indian J Dermatol Venereol Leprol 76(3):270–272

    Article  CAS  PubMed  Google Scholar 

  • Wong TY, Mihm MC Jr (1994) Acantholytic dermatosis localized to genitalia and crural areas of male patients: a report of three cases. J Cutan Pathol 21(1):27–32

    Article  CAS  PubMed  Google Scholar 

  • Wong KT, Wong KK (1994) A case of acantholytic dermatosis of the vulva with features of pemphigus vegetans. J Cutan Pathol 21:453–456

    Article  CAS  PubMed  Google Scholar 

  • Wu IB, Schwartz RA (2008) Reiter’s syndrome: the classic triad and more. J Am Acad Dermatol 59(1):113–121

    Article  PubMed  Google Scholar 

  • Yadav S, Singh P, Hemal A, Kumar R (2017) Genital tuberculosis: current status of diagnosis and management. Transl Androl Urol 6(2):222–233

    Article  PubMed  PubMed Central  Google Scholar 

  • Yamamoto T, Yamamoto N, Furuya M, Hayashi A, Koshima I (2016) Genital lymphedema score: genital lymphedema severity scoring system based on subjective symptoms. Ann Plast Surg 77(1):119–121

    Article  CAS  PubMed  Google Scholar 

  • Yarak S, Michalany NS, Heinke T, Stavale JN (2012) Clinical and histopathological characteristics of genital melanocytic nevi: a report of 109 cases and a review of the literature. J Clin Exp Dermatol Res 3:160

    Article  Google Scholar 

  • You Y, Yang X, Hao F, Zhong B (2009) The umbilical polyp: a report of two cases and literature review. Int J Dermatol 48(6):630–632

    Article  PubMed  Google Scholar 

  • Yu JS, Kim KW, Lee HJ, Lee YJ, Yoon CS, Kim MJ (2001) Urachal remnant diseases: spectrum of CT and US findings. Radiographics 21(2):451–461

    Article  CAS  PubMed  Google Scholar 

  • Ząbkowski T, Wajszczuk M (2014) Epidermoid cyst of the scrotum: a clinical case. Urol J 11(3):1706–1709

    PubMed  Google Scholar 

  • Zakka LR, Shetty SS, Ahmed AR (2012) Rituximab in the treatment of pemphigus vulgaris. Dermatol Ther (Heidelb) 2(1):17

    Article  Google Scholar 

  • Zaouak A, Ben Brahim E, Ben Tanfous A, Koubaa W, Sahnoun R, Hammami H, Fenniche S (2018) Mucosal fixed drug eruption due to mefenamic acid: report of a case and a review. Therapie 73(5):433–435

    Article  PubMed  Google Scholar 

  • Zavras N, Christianakis E, Tsamoudaki S, Velaoras K (2012) Infantile perianal pyramidal protrusion: a report of 8 new cases and a review of the literature. Case Rep Dermatol 4(3):202–206

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Zheng JW, Zhang L, Zhou Q, Mai HM, Wang YA, Fan XD, Qin ZP, Wang XK, Zhao YF (2013) A practical guide to treatment of infantile hemangiomas of the head and neck. Int J Clin Exp Med 6(10):851–860

    PubMed  PubMed Central  Google Scholar 

  • Zone JJ, Taylor TB, Meyer LJ, Petersen MJ (1998) The 97 kDa linear IgA bullous disease antigen is identical to a portion of the extracellular domain of the 180 kDa bullous pemphigoid antigen, BPAg2. J Invest Dermatol 110(3):207–210

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Dermatology Department, Katihar Medical College, Katihar, India

    Piyush Kumar

  2. MY Hospital and MGM Medical College, Indore, India

    Sanjay Khare

  3. Dermatology Department, NHL Municipal Medical College and VS Hospital and Sardar Vallabhbhai Patel Institute of Medical Science and Research, Ahmedabad, Gujarat, India

    Santoshdev P. Rathod

  4. Steel City Nursing Home, Jamshedpur, India

    Esther Nimisha

  5. Ruby Hall Clinic and Joshi Hospital, Pune, India

    Meenaz Khoja

  6. Department of Dermatology, Venereology and Leprosy, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Sawangi, Wardha, India

    Sandeep Kulkarni

  7. Department of Dermatology, Venereology and Leprosy, Government Medical College and Hospital, Haldwani, Uttarakhand, India

    Anup Kumar Tiwary

  8. Department of Dermatology, Venereology and Leprosy, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Wardha, India

    Bhushan Madke

Authors
  1. Piyush Kumar
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  2. Sanjay Khare
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  3. Santoshdev P. Rathod
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  4. Esther Nimisha
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  5. Meenaz Khoja
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  6. Sandeep Kulkarni
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  7. Anup Kumar Tiwary
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  8. Bhushan Madke
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Correspondence to Piyush Kumar .

Editor information

Editors and Affiliations

  1. Department of Pathology, Univ of Rochester School of Med, Rochester, NY, USA

    Bruce Smoller

  2. Khorramshahr, Iran

    Nooshin Bagherani

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Kumar, P. et al. (2020). The Genital, Perianal, and Umbilical Regions. In: Smoller, B., Bagherani, N. (eds) Atlas of Dermatology, Dermatopathology and Venereology . Springer, Cham. https://doi.org/10.1007/978-3-319-45134-3_58-1

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  • DOI: https://doi.org/10.1007/978-3-319-45134-3_58-1

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  • Print ISBN: 978-3-319-45134-3

  • Online ISBN: 978-3-319-45134-3

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