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Infarct of Breast Tissue

  • Living reference work entry
  • First Online:
Encyclopedia of Pathology

Part of the book series: Encyclopedia of Pathology ((EP))

  • 68 Accesses

Definition

An infarct is a coagulative necrosis of (breast-) tissue, caused by ischemia. This is mostly not a primary event in breast tissue but rather a secondary one, typically occurring after an invasive procedure or within a breast lesion such as a fibroadenoma, papilloma, or large neoplasm. In rare events, it can occur during late pregnancy or lactation.

Clinical Features

  • Incidence: Primary breast infarction is rare. Only a few case reports exist about breast infarction during the third trimester of pregnancy or lactation (Han et al. 2015; Hasson and Pope 1961).

    Secondary breast infarction sometimes occurs as a complication following core needle biopsy, fine needle aspiration biopsy (FNAB), or a surgical procedure by altering the blood vessels of a breast lesion, which then undergoes infarction.

  • Age: Wide age distribution depending on underlying lesion. Primary infarction is more typical in pregnant women.

  • Sex: Only females, no reported male case.

  • Site: No site preference.

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References and Further Reading

  • Flint, A., & Oberman, H. A. (1984). Infarction and squamous metaplasia of intraductal papilloma: A benign breast lesion that may simulate carcinoma. Human Pathology, 15, 764–767.

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  • Han, B., Zhang, H., Jiang, P., Zheng, C., Bi, L., Lu, L. U., & Fan, Z. (2015). Breast infarction during pregnancy and lactation: A case report. Experimental and Therapeutic Medicine, 10, 1888–1892.

    Article  PubMed  PubMed Central  Google Scholar 

  • Hasson, J., & Pope, C. H. (1961). Mammary infarcts associated with pregnancy presenting as breast tumors. Surgery, 49, 313–316.

    PubMed  CAS  Google Scholar 

  • Isenberg, J. S., Tu, Q., & Rainey, W. (1996). Mammary gangrene associated with warfarin ingestion. Annals of Plastic Surgery, 37, 553–555.

    Article  CAS  PubMed  Google Scholar 

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Author information

Authors and Affiliations

  1. Diagnostic- and Research Institute of Pathology, Medical University of Graz, Graz, Austria

    Peter Regitnig

Authors
  1. Peter Regitnig
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Correspondence to Peter Regitnig .

Editor information

Editors and Affiliations

  1. NIJMEGEN, The Netherlands

    J.H.J.M. van Krieken

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Regitnig, P. (2018). Infarct of Breast Tissue. In: van Krieken, J. (eds) Encyclopedia of Pathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-28845-1_4755-1

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  • DOI: https://doi.org/10.1007/978-3-319-28845-1_4755-1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-28845-1

  • Online ISBN: 978-3-319-28845-1

  • eBook Packages: Springer Reference MedicineReference Module Medicine

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