Abstract
Just as the right arm of the radiation oncologist is the medical physicist, so the heart of brachytherapy is the science of physics. In this chapter we introduce the basics of brachytherapy physics beginning with the core of the science and culminating with a comprehensive presentation of the known science to date.
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Units, I.C.o.R (1991) Measurements: dose and volume specification for reporting intracavitary therapy in gynecology; Repr, vol 38. International commission on radiation units and measurements
Halperin EC, Brady LW, Wazer DE et al (2013) Perez & Brady’s principles and practice of radiation oncology. Lippincott Williams & Wilkins, Philadelphia
NCRP (1985) A handbook of radioactivity measurements procedures. NCRP report 58
Nath R, Anderson LL, Meli JA et al (1997) Code of practice for brachytherapy physics: report of the AAPM Radiation Therapy Committee Task Group No. 56. Med Phys 24(10):1557–1598
Units, I.C.o.R (1998) Fundamental quantities and units for ionizing radiation, vol 58. International commission on radiation
Nath R (1987) Specification of Brachytherapy Source Strength: Report of AAPM Task Group 32
Rivard MJ, Coursey BM, DeWerd LA et al (2004) Update of AAPM Task Group No. 43 Report: A revised AAPM protocol for brachytherapy dose calculations. Med Phys 31(3):633–674
Thomadsen B, Rivard MJ, Butler WM, Medicine, A.A.o.P.i (2005) Brachytherapy physics. American association of physicists in medicine
Richardson S (2012) A 2-year review of recent Nuclear Regulatory Commission events: what errors occur in the modern brachytherapy era? Pract Radiat Oncol 2(3):157–163
Krishnaswamy V (1972) Dose distributions about 137Cs sources in tissue 1. Radiology 105(1):181–184
Paterson JRK, Meredith WJ (1967) Radium dosage: the Manchester system. E. & S. Livingstone, Edinburgh
Glasser O, Quimby H, Taylor LS et al (1961) Physical foundations of radiology. Hoeber, New York, p 581
Rivard MJ, Butler WM, DeWerd LA et al (2007) Supplement to the 2004 update of the AAPM Task Group No. 43 Report. Med Phys 34(6):2187–2205
Fellner C, Pötter R, Knocke TH et al (2001) Comparison of radiography-and computed tomography-based treatment planning in cervix cancer in brachytherapy with specific attention to some quality assurance aspects. Radiother Oncol 58(1):53–62
Gebara WJ, Weeks KJ, Hahn CA et al (1998) Computed axial tomography tandem and ovoids (CATTO) dosimetry: three‐dimensional assessment of bladder and rectal doses. Radiat Oncol Investig 6(6):268–275
Mizoe J (1990) Analysis of the dose-volume histogram in uterine cervical cancer by diagnostic CT. Strahlentherapie und Onkologie: Organ der Deutschen Rontgengesellschaft[et al] 166(4):279–284
Schoeppel SL, Lavigne ML, Martel MK et al (1994) Three-dimensional treatment planning of intracavitary gynecologic implants: analysis of ten cases and implications for dose specification. Int J Radiat Oncol Biol Phys 28(1):277–283
Haie-Meder C, Pötter R, Van Limbergen E et al (2005) Recommendations from Gynaecological (GYN) GEC-ESTRO Working Group☆(I): concepts and terms in 3D image based 3D treatment planning in cervix cancer brachytherapy with emphasis on MRI assessment of GTV and CTV. Radiother Oncol 74(3):235–245
Viswanathan AN, Erickson BA (2010) Three-dimensional imaging in gynecologic brachytherapy: a survey of the American Brachytherapy Society. Int J Radiat Oncol Biol Phys 76(1):104–109
Willins J, Wallner K (1997) CT-based dosimetry for transperineal I-125 prostate brachytherapy. Int J Radiat Oncol Biol Phys 39(2):347–353
Pötter R, Haie-Meder C, Van Limbergen E et al (2006) Recommendations from gynaecological (GYN) GEC ESTRO working group (II): concepts and terms in 3D image-based treatment planning in cervix cancer brachytherapy—3D dose volume parameters and aspects of 3D image-based anatomy, radiation physics, radiobiology. Radiother Oncol 78(1):67–77
Blasko J, Ragde H, Schumacher D (1987) Transperineal percutaneous iodine-125 implantation for prostatic carcinoma using transrectal ultrasound and template guidance. Endocuriether Hypertherm Oncol 3:131–139
Edmundson GK, Yan D, Martinez AA (1995) Intraoperative optimization of needle placement and dwell times for conformal prostate brachytherapy. Int J Radiat Oncol Biol Phys 33(5):1257–1263
Holm H, Juul N, Pedersen J et al (2002) Transperineal 125 iodine seed implantation in prostatic cancer guided by transrectal ultrasonography. J Urol 167(2):985–988
Vicini FA, Jaffray DA, Horwitz EM et al (1998) Implementation of 3D-virtual brachytherapy in the management of breast cancer: a description of a new method of interstitial brachytherapy. Int J Radiat Oncol Biol Phys 40(3):629–635
Nag S, Cardenes H, Chang S et al (2004) Proposed guidelines for image-based intracavitary brachytherapy for cervical carcinoma: report from Image-Guided Brachytherapy Working Group. Int J Radiat Oncol Biol Phys 60(4):1160–1172
Ménard C, Susil RC, Choyke P et al (2004) MRI-guided HDR prostate brachytherapy in standard 1.5 T scanner. Int J Radiat Oncol Biol Phys 59(5):1414–1423
Pouliot J, Kim Y, Lessard E et al (2004) Inverse planning for HDR prostate brachytherapy used to boost dominant intraprostatic lesions defined by magnetic resonance spectroscopy imaging. Int J Radiat Oncol Biol Phys 59(4):1196–1207
Viswanathan AN, Dimopoulos J, Kirisits C et al (2007) Computed tomography versus magnetic resonance imaging-based contouring in cervical cancer brachytherapy: results of a prospective trial and preliminary guidelines for standardized contours. Int J Radiat Oncol Biol Phys 68(2):491–498
Malyapa RS, Mutic S, Low DA et al (2002) Physiologic FDG-PET three-dimensional brachytherapy treatment planning for cervical cancer. Int J Radiat Oncol Biol Phys 54(4):1140–1146
Lin LL, Mutic S, Low DA et al (2007) Adaptive brachytherapy treatment planning for cervical cancer using FDG-PET. Int J Radiat Oncol Biol Phys 67(1):91–96
Mutic S, Grigsby PW, Low DA et al (2002) PET-guided three-dimensional treatment planning of intracavitary gynecologic implants. Int J Radiat Oncol Biol Phys 52(4):1104–1110
Lessard E, Pouliot J (2001) Inverse planning anatomy-based dose optimization for HDR-brachytherapy of the prostate using fast simulated annealing algorithm and dedicated objective function. Med Phys 28(5):773–779
Lee EK, Gallagher RJ, Silvern D et al (1999) Treatment planning for brachytherapy: an integer programming model, two computational approaches and experiments with permanent prostate implant planning. Phys Med Biol 44(1):145
Lachance B, Béliveau-Nadeau D, Lessard É et al (2002) Early clinical experience with anatomy-based inverse planning dose optimization for high-dose-rate boost of the prostate. Int J Radiat Oncol Biol Phys 54(1):86–100
Lahanas M, Baltas D, Giannouli S (2003) Global convergence analysis of fast multiobjective gradient-based dose optimization algorithms for high-dose-rate brachytherapy. Phys Med Biol 48(5):599
Milickovic N, Lahanas M, Papagiannopoulou M et al (2002) Multiobjective anatomy-based dose optimization for HDR-brachytherapy with constraint free deterministic algorithms. Phys Med Biol 47(13):2263
Pouliot J, Tremblay D, Roy J et al (1996) Optimization of permanent 125 I prostate implants using fast simulated annealing. Int J Radiat Oncol Biol Phys 36(3):711–720
Tedgren ÅC, Ahnesjö A (2008) Optimization of the computational efficiency of a 3D, collapsed cone dose calculation algorithm for brachytherapy. Med Phys 35(4):1611–1618
Zourari K, Pantelis E, Moutsatsos A et al (2010) Dosimetric accuracy of a deterministic radiation transport based I192r brachytherapy treatment planning system. Part I: single sources and bounded homogeneous geometries. Med Phys 37(2):649–661
Petrokokkinos L, Zourari K, Pantelis E et al (2011) Dosimetric accuracy of a deterministic radiation transport based I192r brachytherapy treatment planning system. Part II: Monte Carlo and experimental verification of a multiple source dwell position plan employing a shielded applicator. Med Phys 38(4):1981–1992
Zourari K, Pantelis E, Moutsatsos A et al (2013) Dosimetric accuracy of a deterministic radiation transport based 192Ir brachytherapy treatment planning system. Part III. Comparison to Monte Carlo simulation in voxelized anatomical computational models. Med Phys 40(1):011712
Mikell JK, Klopp AH, Price M et al (2013) Commissioning of a grid-based Boltzmann solver for cervical cancer brachytherapy treatment planning with shielded colpostats. Brachytherapy 12(6):645–653
Thomson R, Taylor T, Rogers D (2008) Monte Carlo dosimetry for I125 and Pd103 eye plaque brachytherapy. Med Phys 35(12):5530–5543
Carrier JF, D’Amours M, Verhaegen F et al (2007) Postimplant dosimetry using a Monte Carlo dose calculation engine: a new clinical standard. Int J Radiat Oncol Biol Phys 68(4):1190–1198
Poon E, Williamson JF, Vuong T et al (2008) Patient-specific Monte Carlo dose calculations for high-dose-rate endorectal brachytherapy with shielded intracavitary applicator. Int J Radiat Oncol Biol Phys 72(4):1259–1266
Poon E, Le Y, Williamson JF et al (2008) BrachyGUI: an adjunct to an accelerated Monte Carlo photon transport code for patient-specific brachytherapy dose calculations and analysis. J Phys Conference Series 102:012018, IOP Publishing
Papagiannis P, Pantelis E, Karaiskos P (2014) Current state of the art brachytherapy treatment planning dosimetry algorithms. Br J Radiol 87(1041):20140163
Rivard MJ, Venselaar JL, Beaulieu L (2009) The evolution of brachytherapy treatment planning. Med Phys 36(6):2136–2153
Beaulieu L, Tedgren ÅC, Carrier JF et al (2012) Report of the Task Group 186 on model-based dose calculation methods in brachytherapy beyond the TG-43 formalism: current status and recommendations for clinical implementation. Med Phys 39(10):6208–6236
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Schubert, L.K., Miften, M. (2016). The Physics of Brachytherapy. In: Montemaggi, P., Trombetta, M., Brady, L. (eds) Brachytherapy. Medical Radiology(). Springer, Cham. https://doi.org/10.1007/978-3-319-26791-3_3
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DOI: https://doi.org/10.1007/978-3-319-26791-3_3
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