Abstract
Q1 What is hepatorenal syndrome?
Hepatorenal syndrome (HRS) is defined as the occurrence of renal failure in a patient with advanced liver disease in the absence of an identifiable cause of renal failure. It is a diagnosis of exclusion. More commonly a complication of chronic liver disease, HRS will develop in up to 40 % of patients with advanced cirrhosis and ascites by 5 years. HRS can also complicate acute liver failure in those who present with fulminant hepatic failure of any cause (e.g. severe alcoholic or viral hepatitis).
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Further Reading
Davenport A, et al. Medical management of hepatorenal syndrome. Nephrol Dial Transplant. 2012;27:34–41.
European Association for Study of the Liver. EASL clinical practice guidelines on the management of ascites, spontaneous bacterial peritonitis, and hepatorenal syndrome in cirrhosis. J Hepatol. 2010;53:397–417.
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Findlay, M., Isles, C. (2015). Hepatorenal Syndrome. In: Clinical Companion in Nephrology. Springer, Cham. https://doi.org/10.1007/978-3-319-14868-7_13
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DOI: https://doi.org/10.1007/978-3-319-14868-7_13
Publisher Name: Springer, Cham
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