Skip to main content
SpringerLink
Log in
Book cover

Hemostasis and Thrombosis pp 125–131Cite as

Warfarin

  • Chapter
  • First Online:

Abstract

This chapter reviews the pharmacology and use of warfarin. Dosing and complications such as bleeding and skin necrosis are discussed. Peri-surgical management, reversal of bleeding, management of unstable INR, and restarting after bleeding are also discussed.

This is a preview of subscription content, log in via an institution.

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   69.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Suggested Reading

  • Ageno W, Gallus AS, Wittkowsky A, Crowther M, Hylek EM, Palareti G; American College of Chest Physicians. Oral anticoagulant therapy: antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest. 2012;141 (2 Suppl):e44S–88S.

    Google Scholar 

  • Deloughery TG. Anticoagulation in patients with atrial fibrillation and prosthetic cardiac valves. In: Kitchens CS, Konkle BA, Kessler C, editors. Consultative hemostasis and thrombosis, Chap 47. Philadelphia, PA: W. B. Sanders; 2013. p. 785–99.

    Google Scholar 

  • Lamberts M, Gislason GH, Lip GY, Lassen JF, Bjerring Olesen J, Mikkelsen AP, Sørensen R, Køber L, Torp-Pedersen C, Hansen ML. Antiplatelet therapy for stable coronary artery disease in atrial fibrillation patients on oral anticoagulant: a nationwide cohort study. Circulation. 2014;129(15):1577–85.

    Article  CAS  PubMed  Google Scholar 

  • Nieto JA, Bruscas MJ, Ruiz-Ribo D, Trujillo-Santos J, Valle R, Ruiz-Gimenez N, Monreal M, RIETE Investigators. Acute venous thromboembolism in patients with recent major bleeding. The influence of the site of bleeding and the time elapsed on outcome. J Thromb Haemost. 2006;4(11):2367–72.

    Article  CAS  PubMed  Google Scholar 

  • Patel JP, Arya R. The current status of bridging anticoagulation. Br J Haematol. 2014;164(5):619–29. doi:10.1111/bjh.12644. Epub 2013 Nov 13.

    Article  CAS  PubMed  Google Scholar 

  • Qureshi W, Mittal C, Patsias I, Garikapati K, Kuchipudi A, Cheema G, Elbatta M, Alirhayim Z, Khalid F. Restarting anticoagulation and outcomes after major gastrointestinal bleeding in atrial fibrillation. Am J Cardiol. 2014;113(4):662–8.

    Article  CAS  PubMed  Google Scholar 

  • Quinlan DJ, Eikelboom JW, Weitz JI. Four-factor prothrombin complex concentrate for urgent reversal of vitamin K antagonists in patients with major bleeding. Circulation. 2013;128(11):1179–81.

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Pathology and Pediatrics, Oregon Health and Science University, Portland, OR, 97239, USA

    Thomas G. DeLoughery M.D., F.A.C.P., F.A.W.M. (Professor of Medicine)

Authors
  1. Thomas G. DeLoughery M.D., F.A.C.P., F.A.W.M.
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Thomas G. DeLoughery M.D., F.A.C.P., F.A.W.M. .

Editor information

Editors and Affiliations

  1. Medicine, Pathology, and Pediatrics, Oregon Health & Science University, Portland, Oregon, USA

    Thomas G. DeLoughery

Rights and permissions

Reprints and permissions

Copyright information

© 2015 Springer International Publishing Switzerland

About this chapter

Cite this chapter

DeLoughery, T.G. (2015). Warfarin. In: DeLoughery, T. (eds) Hemostasis and Thrombosis. Springer, Cham. https://doi.org/10.1007/978-3-319-09312-3_25

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-09312-3_25

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-09311-6

  • Online ISBN: 978-3-319-09312-3

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation