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Analysis of US FDA-Approved Drugs Containing Sulfur Atoms

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Sulfur Chemistry

Part of the book series: Topics in Current Chemistry Collections ((TCCC))

Abstract

In this review, we discuss all sulfur-containing FDA-approved drugs and their structures. The second section of the review is dedicated to structural analysis and is divided into 14 subsections, each focusing on one type of sulfur-containing moiety. A concise graphical representation of each class features drugs that are organized on the basis of structural similarity, evolutionary relevance, and medical indication. This review offers a unique and comprehensive overview of the structural features of all sulfur-containing FDA-approved drugs to date.

Chapter 1 was originally published as Scott, K. A. & Njardarson, J. T. Top Curr Chem (Z) (2018) 376: 5. https://doi.org/10.1007/s41061-018-0184-5.

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Abbreviations

6-APA:

6-Aminopenicillanic acid

ADP:

Adenosine diphosphate

cGMP:

Cyclic guanosine monophosphate

COX-2:

Cyclooxygenase-2

GERD:

Gastroesophageal reflux disease

GPCR:

G protein-coupled receptor

HIV:

Human immunodeficiency virus

mRNA:

Messenger RNA

NSAID:

Nonsteroidal anti-inflammatory drugs

SMN1:

Survival motor neuron 1

Author information

Authors and Affiliations

  1. Department of Chemistry and Biochemistry, University of Arizona, Tucson, AZ, 85721, USA

    Kevin A. Scott & Jon T. Njardarson

  2. Department of Pharmacology and Toxicology, University of Arizona, Tucson, AZ, 85721, USA

    Kevin A. Scott

Authors
  1. Kevin A. Scott
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  2. Jon T. Njardarson
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Corresponding author

Correspondence to Jon T. Njardarson .

Editor information

Editors and Affiliations

  1. School of Chemistry & Molecular Engineering, East China Normal University , Shanghai, China

    Xuefeng Jiang

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Scott, K.A., Njardarson, J.T. (2019). Analysis of US FDA-Approved Drugs Containing Sulfur Atoms. In: Jiang, X. (eds) Sulfur Chemistry. Topics in Current Chemistry Collections. Springer, Cham. https://doi.org/10.1007/978-3-030-25598-5_1

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