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Gastric Cancer In The Precision Medicine Era pp 43–52Cite as

Diagnosis and Surveillance: Endoscopic Hallmarks

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Part of the book series: Current Clinical Pathology ((CCPATH))

Abstract

Esophagogastroduodenoscopy (EGD) is the diagnostic imaging procedure of choice in initial step of diagnosis of gastric carcinoma. EGD is a highly sensitive and specific diagnostic test, especially if combined with endoscopic macrobiopsies and histological examination of the tissue. Today technological advances permit a better diagnosis of tumors, thanks to the use of different technologies in combination with endoscopy. Some examples of new technologies are chromoendoscopy and magnification endoscopy that are useful to improve visualization of mucosal details, narrowband imaging that evaluates the capillary pattern correlated with the degree of parietal infiltration of the neoplasm, and last but not least confocal laser endomicroscopy that permits in vivo analysis of tissue microarchitecture, with cellular resolution, thus allowing a precise identification of areas to be biopsied and an evaluation of neoangiogenesis. The endoscopic diagnosis of early gastric cancer (EGC) requires endoscopic techniques that follow quality standards and thorough knowledge. Moreover, endoscopic ultrasound (EUS) allows more accurate locoregional staging of early or locally advanced gastric cancer.

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Acknowledgments

The authors thank Francesca Masutti for her assistance in manuscript editing.

This work was supported by the following grant of Ministry of Health (RF-2016-02361525 to R.C.).

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Authors and Affiliations

  1. Oncological Gastroenterology Department, IRCCS, CRO Aviano, National Cancer Institute, Aviano, PN, Italy

    Renato Cannizzaro, Raffaella Magris, Stefania Maiero & Mara Fornasarig

  2. Molecular Oncology Unit, IRCCS, CRO Aviano, National Cancer Institute, Aviano, PN, Italy

    Paola Spessotto

  3. Immunopathology and Cancer Biomarkers/Bio-proteomics Facility, Department of Research and Advanced Tumor Diagnostics, IRCCS, CRO Aviano, National Cancer Institute, Aviano, PN, Italy

    Valli De Re

Authors
  1. Renato Cannizzaro
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  2. Raffaella Magris
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  3. Stefania Maiero
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  4. Paola Spessotto
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  5. Valli De Re
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  6. Mara Fornasarig
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Corresponding author

Correspondence to Renato Cannizzaro .

Editor information

Editors and Affiliations

  1. Pathology Unit and Biobank, CRO-Aviano, IRCCS, National Cancer Institute, Aviano, Italy

    Vincenzo Canzonieri

  2. Sbarro Institute for Cancer, Research and Molecular Medicine, Department of Biology, Temple University, Philadelphia, PA, USA

    Antonio Giordano

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Cannizzaro, R., Magris, R., Maiero, S., Spessotto, P., De Re, V., Fornasarig, M. (2019). Diagnosis and Surveillance: Endoscopic Hallmarks. In: Canzonieri, V., Giordano, A. (eds) Gastric Cancer In The Precision Medicine Era. Current Clinical Pathology. Humana, Cham. https://doi.org/10.1007/978-3-030-04861-7_3

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  • DOI: https://doi.org/10.1007/978-3-030-04861-7_3

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  • Publisher Name: Humana, Cham

  • Print ISBN: 978-3-030-04860-0

  • Online ISBN: 978-3-030-04861-7

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